Zobrazeno 1 - 10
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pro vyhledávání: '"Kirk Paul"'
Autor:
Herald, Christopher M., Kirk, Paul
We examine the holonomy-perturbed traceless SU(2) character variety of the trivial four-stranded tangle {p_1,p_2,p_3,p_4} X [0,1] in S^2 X [0,1] equipped with a strong marking, either an earring or a bypass. Viewing these marked tangles as endomorphi
Externí odkaz:
http://arxiv.org/abs/2407.11247
Dose-response prediction in cancer is an active application field in machine learning. Using large libraries of \textit{in-vitro} drug sensitivity screens, the goal is to develop accurate predictive models that can be used to guide experimental desig
Externí odkaz:
http://arxiv.org/abs/2407.00175
Autor:
Kirk, Paul D. W., Rao, Jackie
Effective clustering of biomedical data is crucial in precision medicine, enabling accurate stratifiction of patients or samples. However, the growth in availability of high-dimensional categorical data, including `omics data, necessitates computatio
Externí odkaz:
http://arxiv.org/abs/2406.16227
Clustering is commonly performed as an initial analysis step for uncovering structure in 'omics datasets, e.g. to discover molecular subtypes of disease. The high-throughput, high-dimensional nature of these datasets means that they provide informati
Externí odkaz:
http://arxiv.org/abs/2303.00318
We construct two homology 3-spheres for which the (unperturbed) $SU(2)$ Chern-Simons function is not Morse-Bott. In one case, there is a degenerate isolated critical point. In the other, a path component of the critical set is not homeomorphic to a m
Externí odkaz:
http://arxiv.org/abs/2301.03676
Autor:
Nicholls, Kath1,2 (AUTHOR), Kirk, Paul D. W.1,2,3 (AUTHOR), Wallace, Chris1,2 (AUTHOR) cew54@cam.ac.uk
Publikováno v:
PLoS Computational Biology. 9/3/2024, Vol. 20 Issue 9, p1-17. 17p.
We consider the Bayesian mixture of finite mixtures (MFMs) and Dirichlet process mixture (DPM) models for clustering. Recent asymptotic theory has established that DPMs overestimate the number of clusters for large samples and that estimators from bo
Externí odkaz:
http://arxiv.org/abs/2207.14717
Autor:
Rouanet, Anaïs, Johnson, Rob, Strauss, Magdalena E, Richardson, Sylvia, Tom, Brian D, White, Simon R, Kirk, Paul D W
The identification of sets of co-regulated genes that share a common function is a key question of modern genomics. Bayesian profile regression is a semi-supervised mixture modelling approach that makes use of a response to guide inference toward rel
Externí odkaz:
http://arxiv.org/abs/2111.04518
Autor:
Taylor Graham P, Richardson Sylvia, Stumpf Michael P, Wait Robin, Lewin Alexandra M, Courtney Alan, Witkover Aviva, Kirk Paul, Bangham Charles R
Publikováno v:
Retrovirology, Vol 8, Iss Suppl 1, p A43 (2011)
Externí odkaz:
https://doaj.org/article/c83140ed90e648f79aac0e08d61b4de3