Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kirk M. Maxey"'
Publikováno v:
Survey of Ophthalmology. 47:S34-S40
Using human and bovine corneal tissue, we investigated the in vitro metabolism of bimatoprost (17-phenyl-18,19,20-trinor-prostaglandin F(2alpha) ethyl amide, Lumigan (Allergan, Inc, Irvine, CA). Enzymatic amidase activity, which converts bimatoprost
Publikováno v:
Prostaglandins & Other Lipid Mediators. 62:15-21
Publikováno v:
Prostaglandins & Other Lipid Mediators. 55:301-321
Urinary leukotriene E4 (LTE4) has been used as an index of total leukotriene synthesis. A wide variety of methods have been applied to measure LTE4 which has made direct comparison of urinary levels reported by different laboratories difficult. A new
Publikováno v:
Bioorganicmedicinal chemistry letters. 15(7)
The first total synthesis of 15R-PGD2 3 was accomplished. The approach used in this report is also an efficient method to produce 15R-PGE2. 15R-PGD2, a potential DP2 receptor agonist, could be an important novel tool for defining the role of this rec
Autor:
Joshua Rokach, Seongjin Kim, Domenico Praticò, Sheila H. Jacobo, John A. Lawson, William S. Powell, Garret A. FitzGerald, Kirk M. Maxey
Publikováno v:
Bioorganicmedicinal chemistry letters. 15(6)
The first total synthesis of 17,18,19,20-d4-iPF2alpha-III 32, a deuterated analog of iPF2alpha-III, is described. We have used this analog in some beta-oxidation studies with rat liver homogenates and have shown that 32 was metabolized to 17,18,19,20
Autor:
Krishna R. Maddipati, E E Muirhead, Kirk M. Maxey, Michael Muirhead, B Brooks, L W Byers, James A. Pitcock
Publikováno v:
Blood pressure. 3(6)
Medullipin I (Med I) is a vasodepressor prohormone which is continuously elaborated into the renal venous effluent (RVE) of isolated rat kidneys perfused under high pressure. We have improved the yield of Med I by substituting saline for the albumin
Publikováno v:
Biochemical and Biophysical Research Communications. 100:184-190
Summary Three 11a-carbathromboxane A 2 analogs were synthesized and evaluated for “thromboxane A 2 -like” biological activity in human platelets and rat aortic strips. All three analogs were potent inhibitors of either prostaglandin H 2 or arachi