Zobrazeno 1 - 10
of 523
pro vyhledávání: '"Kirk J, Maurer"'
Autor:
P.Jack Hoopes, Armin D. Tavakkoli, Karen A. Moodie, Kirk J. Maurer, Kenneth R. Meehan, Diana J. Wallin, Ethan Aulwes, Kayla E.A. Duval, Kristen L. Chen, Margaret A.Crary -Burney, Chen Li, Xiaoyao Fan, Linton T. Evans, Keith D. Paulsen
Publikováno v:
Cancer Treatment and Research Communications, Vol 38, Iss , Pp 100789- (2024)
Background: Glioblastoma is the most common primary malignant and treatment-resistant human brain tumor. Rodent models have played an important role in understanding brain cancer biology and treatment. However, due to their small cranium and tumor vo
Externí odkaz:
https://doaj.org/article/ed4ebadcd68c4ee08c9a65edfba55139
Autor:
Charlotte E Egan, Erin K Daugherity, Arlin B Rogers, Delbert S Abi Abdallah, Eric Y Denkers, Kirk J Maurer
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65247 (2013)
Non-alcoholic fatty liver disease (NAFLD) is a common disease with a spectrum of presentations. The current study utilized a lithogenic diet model of NAFLD. The diet was fed to mice that are either resistant (AKR) or susceptible (BALB/c and C57BL/6)
Externí odkaz:
https://doaj.org/article/2d952ef3ea704d31bb3f4661d3e42139
Autor:
Sara B Cohen, Kirk J Maurer, Charlotte E Egan, Steve Oghumu, Abhay R Satoskar, Eric Y Denkers
Publikováno v:
PLoS Pathogens, Vol 9, Iss 10, p e1003706 (2013)
Chemokines and their receptors play a critical role in orchestrating immunity to microbial pathogens, including the orally acquired Th1-inducing protozoan parasite Toxoplasma gondii. Chemokine receptor CXCR3 is associated with Th1 responses, and here
Externí odkaz:
https://doaj.org/article/389cd3f4493f4085b7f76def42d56700
Autor:
Jacqueline J Fremont-Rahl, Zhongming Ge, Carlos Umana, Mark T Whary, Nancy S Taylor, Sureshkumar Muthupalani, Martin C Carey, James G Fox, Kirk J Maurer
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e70657 (2013)
Cholesterol gallstone disease is a complex process involving both genetic and environmental variables. No information exists regarding what role if any the indigenous gastrointestinal microbiota may play in cholesterol gallstone pathogenesis and whet
Externí odkaz:
https://doaj.org/article/f9295f1b35be4326a6e51f0d57b30d1d
Autor:
Barbara A Butcher, Barbara A Fox, Leah M Rommereim, Sung Guk Kim, Kirk J Maurer, Felix Yarovinsky, De'Broski R Herbert, David J Bzik, Eric Y Denkers
Publikováno v:
PLoS Pathogens, Vol 7, Iss 9, p e1002236 (2011)
The ROP16 kinase of Toxoplasma gondii is injected into the host cell cytosol where it activates signal transducer and activator of transcription (STAT)-3 and STAT6. Here, we generated a ROP16 deletion mutant on a Type I parasite strain background, as
Externí odkaz:
https://doaj.org/article/5d5a3e6ddba6441b90a69369ee02286d
Autor:
Kirk J. Maurer, Sangeeta Gohain, Clifford J. Eskey, Periannan Kuppusamy, Karen L Moodie, Harold M. Swartz, Nadeem Khan, Huagang Hou
Publikováno v:
Cell Biochemistry and Biophysics. 75:285-294
Cerebral tissue oxygenation (oxygen tension, pO2) is a critical parameter that is closely linked to brain metabolism, function, and pathophysiology. In this work, we have used electron paramagnetic resonance oximetry with a deep-tissue multi-site oxy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21fc2f15d5f8b5f95496715b95c31612
https://doi.org/10.1007/s12013-017-0798-1
https://doi.org/10.1007/s12013-017-0798-1
Autor:
Luisa Torres, Sudie-Ann Robinson, Leon Toussaint, Do-Geun Kim, Angela Yan, Antje Krenz, Kirk J. Maurer, Margaret S. Bynoe
Publikováno v:
Journal of Neuroinflammation
Background Non-alcoholic fatty liver disease (NAFLD) is a chronic liver disease afflicting about one third of the world’s population and 30 % of the US population. It is induced by consumption of high-lipid diets and is characterized by liver infla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::304fb833f3771986640437f5f2cc5f87
http://europepmc.org/articles/PMC4700622
http://europepmc.org/articles/PMC4700622
Autor:
Robert S. Weiss, Elizabeth S. Moore, Ahmed Al Saei, Arlin B. Rogers, Kirk J. Maurer, Delbert S. Abi Abdallah, Erin K. Daugherity, Gabriel Balmus
Publikováno v:
Cell Cycle. 11:1918-1928
Steatoapoptosis is a hallmark of non-alcoholic fatty liver disease (NAFLD) and is an important factor in liver disease progression. We hypothesized that increased reactive oxygen species resulting from excess dietary fat contribute to liver disease b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b94a644047e67a5a2ccf9972cf5b587
https://doi.org/10.4161/cc.20259
https://doi.org/10.4161/cc.20259
Autor:
Charlotte E. Egan, Sara B. Cohen, Eric Y. Denkers, Kenneth W. Simpson, Matthias Mack, Kirk J. Maurer
Publikováno v:
Mucosal immunology
Oral infection of C57BL/6 mice with Toxoplasma gondii triggers severe necrosis in the ileum within 7-10 days of infection. Lesion development is mediated by Th-1 cytokines, CD4+ T cells, and subepithelial bacterial translocation. As such, these featu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc09273866420d2091d07e691477ce3d
https://doi.org/10.1038/mi.2011.31
https://doi.org/10.1038/mi.2011.31
Publikováno v:
Gastroenterology. 136:425-440
Cholesterol gallstone formation is a complex process mediated by genetic and environmental factors. Until recently, the role of the immune system in the pathogenesis of cholesterol gallstones was not considered a valid topic of research interest. Thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5f1a7132dd65c21b1bb5569fd54de51
https://doi.org/10.1053/j.gastro.2008.12.031
https://doi.org/10.1053/j.gastro.2008.12.031