Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Kirk D C Jensen"'
Autor:
Scott P Souza, Samantha D Splitt, Juan C Sànchez-Arcila, Julia A Alvarez, Jessica N Wilson, Safuwra Wizzard, Zheng Luo, Nicole Baumgarth, Kirk D C Jensen
Publikováno v:
PLoS Pathogens, Vol 17, Iss 12, p e1010081 (2021)
Protective immunity to parasitic infections has been difficult to elicit by vaccines. Among parasites that evade vaccine-induced immunity is Toxoplasma gondii, which causes lethal secondary infections in chronically infected mice. Here we report that
Externí odkaz:
https://doaj.org/article/51630f80687a4dba9e15b4b67857c227
Autor:
Angel K Kongsomboonvech, Felipe Rodriguez, Anh L Diep, Brandon M Justice, Brayan E Castallanos, Ana Camejo, Debanjan Mukhopadhyay, Gregory A Taylor, Masahiro Yamamoto, Jeroen P J Saeij, Michael L Reese, Kirk D C Jensen
Publikováno v:
PLoS Pathogens, Vol 16, Iss 8, p e1008327 (2020)
Host resistance to Toxoplasma gondii relies on CD8 T cell IFNγ responses, which if modulated by the host or parasite could influence chronic infection and parasite transmission between hosts. Since host-parasite interactions that govern this respons
Externí odkaz:
https://doaj.org/article/ca314d4bf76146b69b6fc1defe49177d
Autor:
Julia A. Alvarez, Elisabet Gas-Pascual, Sahil Malhi, Juan C. Sánchez-Arcila, Ferdinand Ngale Njume, Hanke van der Wel, Yanlin Zhao, Laura García-López, Gabriella Ceron, Jasmine Posada, Scott P. Souza, George S. Yap, Christopher M. West, Kirk D. C. Jensen
Publikováno v:
mBio, Vol 15, Iss 10 (2024)
ABSTRACT Glycosylphosphatidylinositols (GPIs) are highly conserved anchors for eukaryotic cell surface proteins. The apicomplexan parasite, Toxoplasma gondii, is a widespread intracellular parasite of warm-blooded animals whose plasma membrane is cov
Externí odkaz:
https://doaj.org/article/e16045143206407581d3f75afa37d03f
Autor:
Angel K. Kongsomboonvech, Laura García-López, Ferdinand Njume, Felipe Rodriguez, Scott P. Souza, Alex Rosenberg, Kirk D. C. Jensen
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
IntroductionToxoplasma gondii induces a strong CD8 T cell response characterized by the secretion of IFNγ that promotes host survival during infection. The initiation of CD8 T cell IFNγ responses in vitro differs widely between clonal lineage strai
Externí odkaz:
https://doaj.org/article/2eef35b30b284a818d2de5862f5266f3
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Forward genetic approaches have been widely used in parasitology and have proven their power to reveal the complexities of host-parasite interactions in an unbiased fashion. Many aspects of the parasite’s biology, including the identification of vi
Externí odkaz:
https://doaj.org/article/a4e92d455d84477e88bce13b47570722
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Over the last century, the alarming surge in allergy and autoimmune disease has led to the hypothesis that decreasing exposure to microbes, which has accompanied industrialization and modern life in the Western world, has fundamentally altered the im
Externí odkaz:
https://doaj.org/article/fe179940f8fc4c419e32320539cfeec6
Autor:
Dan Davini, Kristen M. Valentine, Katrina K. Hoyer, Kirk D. C. Jensen, Genevieve N. Mullins, Mufadhal Al-Kuhlani
Publikováno v:
Scientific reports, vol 10, iss 1
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
IL-2Rα, in part, comprises the high affinity receptor for IL-2, a cytokine important in immune proliferation, activation, and regulation. IL-2Rα deficient mice (IL-2Rα-KO) develop systemic autoimmune disease and die from severe anemia between 18 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eefe4a3c5aba099e14b85eacd817e54
https://escholarship.org/uc/item/9zz2295z
https://escholarship.org/uc/item/9zz2295z
Autor:
Debanjan Mukhopadhyay, Jeroen P. J. Saeij, Angel K. Kongsomboonvech, Brayan E. Castallanos, Kirk D. C. Jensen, Gregory A. Taylor, Brandon M. Justice, Ana Camejo, Michael L. Reese, Felipe Rodriguez, Anh L. Diep, Masahiro Yamamoto
Publikováno v:
PLoS Pathogens
PLoS pathogens, vol 16, iss 8
PLoS Pathogens, Vol 16, Iss 8, p e1008327 (2020)
PLoS pathogens, vol 16, iss 8
PLoS Pathogens, Vol 16, Iss 8, p e1008327 (2020)
Host resistance to Toxoplasma gondii relies on CD8 T cell IFNγ responses, which if modulated by the host or parasite could influence chronic infection and parasite transmission between hosts. Since host-parasite interactions that govern this respons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21ee883bcb4b71414d0cf4d9b8b7f894
https://doi.org/10.1101/2020.01.20.912568
https://doi.org/10.1101/2020.01.20.912568
Publikováno v:
Frontiers Research Topics ISBN: 9782889634026
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aca7c7d9fcca19cfd4e468e4b335c800
https://doi.org/10.3389/978-2-88963-402-6
https://doi.org/10.3389/978-2-88963-402-6
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 11 (2020)
Frontiers in Immunology, Vol 11 (2020)
Over the last century, the alarming surge in allergy and autoimmune disease has led to the hypothesis that decreasing exposure to microbes, which has accompanied industrialization and modern life in the Western world, has fundamentally altered the im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a690d889edcea980104c55b5ef1b5a01
https://pubmed.ncbi.nlm.nih.gov/32117273
https://pubmed.ncbi.nlm.nih.gov/32117273