Inflammasome activation links enteric Salmonella Typhimurium infection to a rapid, cytokine-dependent increase in intestinal mucin release

Autor: Xiao Han, Joannie M. Allaire, Shauna M. Crowley, Jocelyn J. Chan, Kelly Lau, Conghao Zhang, Simon A. Hirota, Kirk Bergstrom, Leigh A. Knodler, Bruce A. Vallance

Publikováno v: Gut Microbes, Vol 16, Iss 1 (2024)

The host restricts Salmonella enterica serovar Typhimurium infection of the gut via inflammasome-dependent sloughing of infected epithelial cells. Here we determined that concurrent caspase 1/11-dependent release of the goblet cell-derived mucin, Muc

Externí odkaz: https://doaj.org/article/6c6253954466475d80d23564be718074

Role of mucin glycosylation in the gut microbiota-brain axis of core 3 O-glycan deficient mice

Autor: Erika Coletto, George M. Savva, Dimitrios Latousakis, Matthew Pontifex, Emmanuelle H. Crost, Laura Vaux, Andrea Telatin, Kirk Bergstrom, David Vauzour, Nathalie Juge

Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)

Abstract Alterations in intestinal mucin glycosylation have been associated with increased intestinal permeability and sensitivity to inflammation and infection. Here, we used mice lacking core 3-derived O-glycans (C3GnT−/−) to investigate the ef

Externí odkaz: https://doaj.org/article/5015c207057d485aa595396c2bc0750d

A Comparative Study of Recent Large Language Models on Generating Hospital Discharge Summaries for Lung Cancer Patients

Autor: Li, Yiming, Li, Fang, Roberts, Kirk, Cui, Licong, Tao, Cui, Xu, Hua

Generating discharge summaries is a crucial yet time-consuming task in clinical practice, essential for conveying pertinent patient information and facilitating continuity of care. Recent advancements in large language models (LLMs) have significantl

Externí odkaz: http://arxiv.org/abs/2411.03805

The JCMT BISTRO Survey: The Magnetic Fields of the IC 348 Star-forming Region

Autor: Choi, Youngwoo, Kwon, Woojin, Pattle, Kate, Arzoumanian, Doris, Bourke, Tyler L., Hoang, Thiem, Hwang, Jihye, Koch, Patrick M., Sadavoy, Sarah, Bastien, Pierre, Furuya, Ray, Lai, Shih-Ping, Qiu, Keping, Ward-Thompson, Derek, Berry, David, Byun, Do-Young, Chen, Huei-Ru Vivien, Chen, Wen Ping, Chen, Mike, Chen, Zhiwei, Ching, Tao-Chung, Cho, Jungyeon, Choi, Minho, Choi, Yunhee, Coudé, Simon, Chrysostomou, Antonio, Chung, Eun Jung, Dai, Sophia, Debattista, Victor, Di Francesco, James, Diep, Pham Ngoc, Doi, Yasuo, Duan, Hao-Yuan, Duan, Yan, Eswaraiah, Chakali, Fanciullo, Lapo, Fiege, Jason, Fissel, Laura M., Franzmann, Erica, Friberg, Per, Friesen, Rachel, Fuller, Gary, Gledhill, Tim, Graves, Sarah, Greaves, Jane, Griffin, Matt, Gu, Qilao, Han, Ilseung, Hasegawa, Tetsuo, Houde, Martin, Hull, Charles L. H., Inoue, Tsuyoshi, Inutsuka, Shu-ichiro, Iwasaki, Kazunari, Jeong, Il-Gyo, Johnstone, Doug, Karoly, Janik, Könyves, Vera, Kang, Ji-hyun, Lacaille, Kevin, Law, Chi-Yan, Lee, Chang Won, Lee, Hyeseung, Lee, Chin-Fei, Lee, Jeong-Eun, Lee, Sang-Sung, Li, Dalei, Li, Di, Li, Guangxing, Li, Hua-bai, Lin, Sheng-Jun, Liu, Hong-Li, Liu, Tie, Liu, Sheng-Yuan, Liu, Junhao, Longmore, Steven, Lu, Xing, Lyo, A-Ran, Mairs, Steve, Matsumura, Masafumi, Matthews, Brenda, Moriarty-Schieven, Gerald, Nagata, Tetsuya, Nakamura, Fumitaka, Nakanishi, Hiroyuki, Ngoc, Nguyen Bich, Ohashi, Nagayoshi, Onaka, Takashi, Park, Geumsook, Parsons, Harriet, Peretto, Nicolas, Priestley, Felix, Pyo, Tae-Soo, Qian, Lei, Rao, Ramprasad, Rawlings, Jonathan, Rawlings, Mark, Retter, Brendan, Richer, John, Rigby, Andrew, Saito, Hiro, Savini, Giorgio, Seta, Masumichi, Sharma, Ekta, Shimajiri, Yoshito, Shinnaga, Hiroko, Soam, Archana, Kang, Miju, Kataoka, Akimasa, Kawabata, Koji, Kemper, Francisca, Kim, Jongsoo, Kim, Shinyoung, Kim, Gwanjeong, Kim, Kyoung Hee, Kim, Mi-Ryang, Kim, Kee-Tae, Kim, Hyosung, Kirchschlager, Florian, Kirk, Jason, Kobayashi, Masato I. N., Kusune, Takayoshi, Kwon, Jungmi, Tamura, Motohide, Tang, Ya-Wen, Tang, Xindi, Tomisaka, Kohji, Tsukamoto, Yusuke, Viti, Serena, Wang, Hongchi, Wang, Jia-Wei, Wu, Jintai, Xie, Jinjin, Yang, Meng-Zhe, Yen, Hsi-Wei, Yoo, Hyunju, Yuan, Jinghua, Yun, Hyeong-Sik, Zenko, Tetsuya, Zhang, Guoyin, Zhang, Yapeng, Zhang, Chuan-Peng, Zhou, Jianjun, Zhu, Lei, de Looze, Ilse, André, Philippe, Dowell, C. Darren, Eden, David, Eyres, Stewart, Falle, Sam, Gouellec, Valentin J. M. Le, Poidevin, Frédérick, van Loo, Sven

We present 850 $\mu$m polarization observations of the IC 348 star-forming region in the Perseus molecular cloud as part of the B-fields In STar-forming Region Observation (BISTRO) survey. We study the magnetic properties of two cores (HH 211 MMS and

Externí odkaz: http://arxiv.org/abs/2411.01960

Attosecond Coherent Electron Motion in a Photoionized Aromatic Molecule

Autor: Driver, Taran, Guo, Zhaoheng, Isele, Erik, Grell, Gilbert, Ruberti, Marco, ONeal, Jordan T., Alexander, Oliver, Beauvarlet, Sandra, Cesar, David, Duris, Joseph, Garratt, Douglas, Larsen, Kirk A., Li, Siqi, Kolorenč, Přemysl, McCracken, Gregory A., Tuthill, Daniel, Wang, Zifan, Berrah, Nora, Bostedt, Christoph, Borne, Kurtis, Cheng, Xinxin, DiMauro, Louis F., Doumy, Gilles, Franz, Paris L., Kamalov, Andrei, Li, Xiang, Lin, Ming-Fu, Obaid, Razib, Picón, Antonio, Robles, River R., Rolles, Daniel, Rudenko, Artem, Shaikh, Moniruzzaman, Slaughter, Daniel S., Sudar, Nicholas S., Thierstein, Emily, Ueda, Kiyoshi, Wang, Enliang, Wang, Anna L., Weber, Thorsten, Wolf, Thomas J. A., Young, Linda, Zhang, Zhen, Averbukh, Vitali, Gessner, Oliver, Bucksbaum, Philip H., Kling, Matthias F., Palacios, Alicia, Martín, Fernando, Marangos, Jon P., Walter, Peter, Marinelli, Agostino, Cryan, James P.

In molecular systems, the ultrafast motion of electrons initiates the process of chemical change. Tracking this electronic motion across molecules requires coupling attosecond time resolution to atomic-scale spatial sensitivity. In this work, we empl

Externí odkaz: http://arxiv.org/abs/2411.01700