Zobrazeno 1 - 10
of 4 545
pro vyhledávání: '"Kirk, E."'
Autor:
Graff, David E., Pyzer-Knapp, Edward O., Jordan, Kirk E., Shakhnovich, Eugene I., Coley, Connor W.
Quantitative structure-property relationships (QSPRs) aid in understanding molecular properties as a function of molecular structure. When the correlation between structure and property weakens, a dataset is described as "rough," but this characteris
Externí odkaz:
http://arxiv.org/abs/2305.08238
Autor:
Duan C. Copeland, Vincent A. Ricigliano, Brendon M. Mott, Oliver L. Kortenkamp, Robert J. Erickson, June Gorrochategui-Ortega, Kirk E. Anderson
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract The health of honey bee queens is crucial for colony success, particularly during stressful periods like overwintering. To accompany a previous longitudinal study of colony and worker health, we explored niche-specific gut microbiota, host g
Externí odkaz:
https://doaj.org/article/5217e48efef64680aec318e5ccd51404
Autor:
Thomas J. Peters, Kirk E. Jordan, Ji Li, Kirk Gardner, Breanndan Ó. Conchúir, William C. Swope, Vassilis Vassiliadis, Michael A. Johnston, Peter Zaffetti
Publikováno v:
ACS Omega, Vol 9, Iss 14, Pp 16084-16088 (2024)
Externí odkaz:
https://doaj.org/article/6bc7f9b43fe1400c9f0e5725e919bacf
Autor:
Kirk E. Anderson, Duan C. Copeland
Publikováno v:
Frontiers in Bee Science, Vol 2 (2024)
The microbiome of the honey bee worker hindgut has been explored thoroughly with culturing and next-generation sequencing revealing both composition and function. However, less effort has been devoted to the aerobic social niches associated with the
Externí odkaz:
https://doaj.org/article/0e1015c7504d47f0b1bcc196d4d06904
Autor:
Aldeghi, Matteo, Graff, David E., Frey, Nathan, Morrone, Joseph A., Pyzer-Knapp, Edward O., Jordan, Kirk E., Coley, Connor W.
Publikováno v:
J. Chem. Inf. Model. 2022, 62, 19, 4660-4671
In molecular discovery and drug design, structure-property relationships and activity landscapes are often qualitatively or quantitatively analyzed to guide the navigation of chemical space. The roughness (or smoothness) of these molecular property l
Externí odkaz:
http://arxiv.org/abs/2207.09250
Autor:
Kirk E. Anderson, Nathan O. Allen, Duan C. Copeland, Oliver L. Kortenkamp, Robert Erickson, Brendon M. Mott, Randy Oliver
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Probiotics are widely used in agriculture including commercial beekeeping, but there is little evidence supporting their effectiveness. Antibiotic treatments can greatly distort the gut microbiome, reducing its protective abilities and facil
Externí odkaz:
https://doaj.org/article/8e17a595c1e34bf9a3be7728345536b6
Autor:
Graff, David E., Aldeghi, Matteo, Morrone, Joseph A., Jordan, Kirk E., Pyzer-Knapp, Edward O., Coley, Connor W.
High-throughput virtual screening is an indispensable technique utilized in the discovery of small molecules. In cases where the library of molecules is exceedingly large, the cost of an exhaustive virtual screen may be prohibitive. Model-guided opti
Externí odkaz:
http://arxiv.org/abs/2205.01753
Publikováno v:
Frontiers in Public Health, Vol 12 (2024)
Substance use disorders contribute to considerable U.S. morbidity and mortality. While effective pharmacotherapy options are available to treat opioid and alcohol use disorders, for a variety of reasons, many patients lack access to treatment or may
Externí odkaz:
https://doaj.org/article/e7793f84c2834680b4b90f6acc2b9f6f
Publikováno v:
In American Journal of Pharmaceutical Education August 2024 88(8)