High susceptibility to zoliflodacin and conserved target (GyrB) for zoliflodacin among 1209 consecutive clinical Neisseria gonorrhoeae isolates from 25 European countries, 2018

Autor: Ahlstrand J, Sánchez-Busó L, Day M, Aanensen D, Golparian D, Jacobsson S, Cole MJ, Torreblanca RA, Ásmundsdóttir LR, Balla E, De Baetselier I, Bercot B, Carannante A, Caugant D, Borrego MJ, Buder S, Cassar R, Cole M, Dam A, Eder C, Hoffmann S, Hunjak B, Jeverica S, Kirjavainen V, Maikanti-Charalambous P, Miriagou V, Mlynarczyk-Bonikowska B, Pakarna G, Patterson L, Pavlik P, Perrin M, Shepherd J, Stefanelli P, Unemo M, Jelena V, Zákoucká H

Publikováno v: JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
r-FISABIO: Repositorio Institucional de Producción Científica
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
r-FISABIO. Repositorio Institucional de Producción Científica
instname

Objectives: Novel antimicrobials for treatment of gonorrhoea are imperative. The first-in-class spiropyrimidinetrione zoliflodacin is promising and currently in an international Phase 3 randomized controlled clinical trial (RCT) for treatment of unco

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::179b516fc946620d5b6b82af32f4e2a6
https://fundanet.fisabio.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=8929

The phylodynamics of SARS-CoV-2 during 2020 in Finland.

Autor: Truong Nguyen P; Department of Virology, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Kant R; Department of Virology, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; Department of Veterinary Biosciences, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland., Van den Broeck F; Department of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, Leuven, Belgium.; Department of Biomedical Sciences, Institute of Tropical Medicine, Antwerp, Belgium., Suvanto MT; Department of Virology, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; Department of Veterinary Biosciences, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland., Alburkat H; Department of Virology, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Virtanen J; Department of Virology, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; Department of Veterinary Biosciences, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland., Ahvenainen E; Department of Virology, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Castren R; Department of Virology, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Hong SL; Department of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, Leuven, Belgium., Baele G; Department of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, Leuven, Belgium., Ahava MJ; HUS Diagnostic Center, HUSLAB, Clinical Microbiology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Jarva H; HUS Diagnostic Center, HUSLAB, Clinical Microbiology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.; Translational Immunology Research Program, University of Helsinki, Helsinki, Finland.; Department of Bacteriology and Immunology, University of Helsinki, Helsinki, Finland., Jokiranta ST; Translational Immunology Research Program, University of Helsinki, Helsinki, Finland.; Department of Bacteriology and Immunology, University of Helsinki, Helsinki, Finland., Kallio-Kokko H; HUS Diagnostic Center, HUSLAB, Clinical Microbiology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Kekäläinen E; HUS Diagnostic Center, HUSLAB, Clinical Microbiology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.; Translational Immunology Research Program, University of Helsinki, Helsinki, Finland., Kirjavainen V; HUS Diagnostic Center, HUSLAB, Clinical Microbiology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Kortela E; Infectious Diseases, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Kurkela S; HUS Diagnostic Center, HUSLAB, Clinical Microbiology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Lappalainen M; HUS Diagnostic Center, HUSLAB, Clinical Microbiology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Liimatainen H; HUS Diagnostic Center, HUSLAB, Clinical Microbiology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Suchard MA; Departments of Biomathematics, Biostatistics and Human Genetics, University of California, Los Angeles (UCLA), Los Angeles, CA USA., Hannula S; Institute for Molecular Medicine Finland (FIMM), Helsinki, Finland., Ellonen P; Institute for Molecular Medicine Finland (FIMM), Helsinki, Finland., Sironen T; Department of Virology, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; Department of Veterinary Biosciences, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland., Lemey P; Department of Microbiology, Immunology and Transplantation, Rega Institute, KU Leuven, Leuven, Belgium., Vapalahti O; Department of Virology, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; Department of Veterinary Biosciences, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland.; HUS Diagnostic Center, HUSLAB, Clinical Microbiology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Smura T; Department of Virology, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; HUS Diagnostic Center, HUSLAB, Clinical Microbiology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.

Publikováno v: Communications medicine [Commun Med (Lond)] 2022 Jun 10; Vol. 2, pp. 65. Date of Electronic Publication: 2022 Jun 10 (Print Publication: 2022).

Real-life clinical sensitivity of SARS-CoV-2 RT-PCR test in symptomatic patients.

Autor: Kortela E; Division of Infectious Diseases, Inflammation Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland., Kirjavainen V; HUSLAB Clinical Microbiology, HUS Diagnostic Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Ahava MJ; HUSLAB Clinical Microbiology, HUS Diagnostic Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Jokiranta ST; Translational Immunology Research Program and Department of Bacteriology and Immunology, University of Helsinki, Helsinki, Finland., But A; Biostatistics Consulting, Department of Public Health, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Lindahl A; Department of Respiratory Medicine, Heart and Lung Center, Helsinki University Hospital, University of Helsinki, Helsinki, Finland., Jääskeläinen AE; HUSLAB Clinical Microbiology, HUS Diagnostic Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Jääskeläinen AJ; HUSLAB Clinical Microbiology, HUS Diagnostic Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Järvinen A; Division of Infectious Diseases, Inflammation Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland., Jokela P; HUSLAB Clinical Microbiology, HUS Diagnostic Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Kallio-Kokko H; HUSLAB Clinical Microbiology, HUS Diagnostic Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Loginov R; HUSLAB Clinical Microbiology, HUS Diagnostic Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Mannonen L; HUSLAB Clinical Microbiology, HUS Diagnostic Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Ruotsalainen E; Division of Infectious Diseases, Inflammation Center, Helsinki University Hospital and University of Helsinki, Helsinki, Finland., Sironen T; Department of Virology, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; Department of Veterinary Biosciences, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland., Vapalahti O; HUSLAB Clinical Microbiology, HUS Diagnostic Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.; Department of Virology, Faculty of Medicine, University of Helsinki, Helsinki, Finland.; Department of Veterinary Biosciences, Faculty of Veterinary Medicine, University of Helsinki, Helsinki, Finland., Lappalainen M; HUSLAB Clinical Microbiology, HUS Diagnostic Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Kreivi HR; Department of Respiratory Medicine, Heart and Lung Center, Helsinki University Hospital, University of Helsinki, Helsinki, Finland., Jarva H; HUSLAB Clinical Microbiology, HUS Diagnostic Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.; Translational Immunology Research Program and Department of Bacteriology and Immunology, University of Helsinki, Helsinki, Finland., Kurkela S; HUSLAB Clinical Microbiology, HUS Diagnostic Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland., Kekäläinen E; HUSLAB Clinical Microbiology, HUS Diagnostic Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.; Translational Immunology Research Program and Department of Bacteriology and Immunology, University of Helsinki, Helsinki, Finland.

Publikováno v: PloS one [PLoS One] 2021 May 21; Vol. 16 (5), pp. e0251661. Date of Electronic Publication: 2021 May 21 (Print Publication: 2021).

Verification of UriSed 3 PRO automated urine microscope in regional laboratory environment.

Autor: Kouri T; Department of Clinical Chemistry, HUSLAB, Helsinki University Hospital, HUS Diagnostic Center, FIN-00029 HUS, Helsinki, Finland; Department of Clinical Chemistry, University of Helsinki, Finland. Electronic address: timo.kouri@helsinki.fi., Alagrund K; Department of Clinical Chemistry, HUSLAB, Helsinki University Hospital, HUS Diagnostic Center, FIN-00029 HUS, Helsinki, Finland., Lehtonen M; Department of Clinical Chemistry, HUSLAB, Helsinki University Hospital, HUS Diagnostic Center, FIN-00029 HUS, Helsinki, Finland., Tohmola N; Department of Clinical Chemistry, HUSLAB, Helsinki University Hospital, HUS Diagnostic Center, FIN-00029 HUS, Helsinki, Finland., Pihlajamaa T; Department of Clinical Chemistry, HUSLAB, Helsinki University Hospital, HUS Diagnostic Center, FIN-00029 HUS, Helsinki, Finland., Kouri VP; Department of Clinical Chemistry, HUSLAB, Helsinki University Hospital, HUS Diagnostic Center, FIN-00029 HUS, Helsinki, Finland., Friman S; Department of Clinical Chemistry, HUSLAB, Helsinki University Hospital, HUS Diagnostic Center, FIN-00029 HUS, Helsinki, Finland., Holma T; Department of Clinical Microbiology, HUSLAB, Helsinki University Hospital, HUS Diagnostic Center, FIN-00029 HUS, Helsinki, Finland., Kirjavainen V; Department of Clinical Microbiology, HUSLAB, Helsinki University Hospital, HUS Diagnostic Center, FIN-00029 HUS, Helsinki, Finland., Pätäri-Sampo A; Department of Clinical Microbiology, HUSLAB, Helsinki University Hospital, HUS Diagnostic Center, FIN-00029 HUS, Helsinki, Finland., Lempiäinen A; Department of Clinical Chemistry, HUSLAB, Helsinki University Hospital, HUS Diagnostic Center, FIN-00029 HUS, Helsinki, Finland.

Publikováno v: Clinica chimica acta; international journal of clinical chemistry [Clin Chim Acta] 2021 Apr; Vol. 515, pp. 96-103. Date of Electronic Publication: 2021 Jan 16.

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