Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Kirill S. Nikolsky"'
Autor:
Denis V. Petrovskiy, Kirill S. Nikolsky, Liudmila I. Kulikova, Vladimir R. Rudnev, Tatiana V. Butkova, Kristina A. Malsagova, Arthur T. Kopylov, Anna L. Kaysheva
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract The primary objective of analyzing the data obtained in a mass spectrometry-based proteomic experiment is peptide and protein identification, or correct assignment of the tandem mass spectrum to one amino acid sequence. Comparison of empiric
Externí odkaz:
https://doaj.org/article/67db65e99f694b26a143ce635b8ee83d
Autor:
Denis V. Petrovskiy, Tatiana V. Butkova, Kirill S. Nikolsky, Arthur T. Kopylov, Valeriya I. Nakhod, Liudmila I. Kulikova, Kristina A. Malsagova, Nikolai D. Kibrik, Vladimir R. Rudnev, Alexander A. Izotov, Anna L. Kaysheva
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
IntroductionThe high prevalence of schizophrenia worldwide makes it necessary to proceed from subjective assessment of patient’s clinical symptoms in diagnosis making to searching for circulating blood biomarkers. On the one hand, searching for mol
Externí odkaz:
https://doaj.org/article/aebba2c19e9945a7936d47cdca877126
Autor:
Kirill S. Nikolsky, Liudmila I. Kulikova, Denis V. Petrovskiy, Vladimir R. Rudnev, Kristina A. Malsagova, Anna L. Kaysheva
Publikováno v:
Biomolecules, Vol 13, Iss 11, p 1564 (2023)
Modification of the protein after synthesis (PTM) often affects protein function as supported by numerous studies. However, there is no consensus about the degree of structural protein changes after modification. For phosphorylation of serine, threon
Externí odkaz:
https://doaj.org/article/b434ed3108024cbcaea1f45b0b739bdc
Autor:
Denis V. Petrovsky, Vasiliy I. Pustovoyt, Kirill S. Nikolsky, Kristina A. Malsagova, Arthur T. Kopylov, Alexander A. Stepanov, Vladimir. R. Rudnev, Evgenii I. Balakin, Anna L. Kaysheva
Publikováno v:
Sports, Vol 10, Iss 10, p 160 (2022)
Training and competitive periods can temporarily impair the performance of an athlete. This disruption can be short- or long-term, lasting up to several days. We analyzed the health indicators of 3661 athletes during an in-depth medical examination.
Externí odkaz:
https://doaj.org/article/9f4ea665e28a4112adc23ced98035868
Publikováno v:
Pharmaceuticals, Vol 15, Iss 1, p 30 (2021)
Rheumatoid arthritis (RA) is a chronic disease characterized by bone joint damage and incapacitation. The mechanism underlying RA pathogenesis is autoimmunity in the connective tissue. Cytokines play an important role in the human immune system for s
Externí odkaz:
https://doaj.org/article/30e64dd1c02341e5890ca61160d6d568
Autor:
Maxim S. Kondratyev, Vladimir R. Rudnev, Kirill S. Nikolsky, Denis V. Petrovsky, Liudmila I. Kulikova, Kristina A. Malsagova, Alexander A. Stepanov, Arthur T. Kopylov, Anna L. Kaysheva
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 24; Pages: 16096
Herein, we aimed to highlight current “gaps” in the understanding of the potential interactions between the Anle138b isomer ligand, a promising agent for clinical research, and the intrinsically disordered alpha-synuclein protein. The presence of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3b01a91b4f4a080f63258b6a5cdb1a5
Autor:
Vladimir R. Rudnev, Kirill S. Nikolsky, Denis V. Petrovsky, Liudmila I. Kulikova, Anton M. Kargatov, Kristina A. Malsagova, Alexander A. Stepanov, Arthur T. Kopylov, Anna L. Kaysheva, Alexander V. Efimov
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 19; Pages: 11674
This study explored the mechanisms by which the stability of super-secondary structures of the 3β-corner type autonomously outside the protein globule are maintained in an aqueous environment. A molecular dynamic (MD) study determined the behavioral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f671b2408277b3741fa38def75bd89c6
https://pubmed.ncbi.nlm.nih.gov/36232976
https://pubmed.ncbi.nlm.nih.gov/36232976
Autor:
Denis V. Petrovsky, Vladimir R. Rudnev, Kirill S. Nikolsky, Liudmila I. Kulikova, Kristina M. Malsagova, Arthur T. Kopylov, Anna L. Kaysheva
Publikováno v:
International Journal of Molecular Sciences. 23:14813
A super-secondary structure (SSS) is a spatially unique ensemble of secondary structural elements that determine the three-dimensional shape of a protein and its function, rendering SSSs attractive as folding cores. Understanding known types of SSSs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::496b69daa4f5e4e3e08ccbb233a78686
https://doi.org/10.3390/ijms232314813
https://doi.org/10.3390/ijms232314813
Autor:
Vladimir R. Rudnev, Denis V. Petrovsky, Kirill S. Nikolsky, Liudmila I. Kulikova, Alexander A. Stepanov, Kristina A. Malsagova, Anna L. Kaysheva, Alexander V. Efimov
Publikováno v:
Processes; Volume 10; Issue 11; Pages: 2159
In this study, we analyze the occurrence of the unique structural motif, the 3β-corner, belonging to the Structural Classification of Proteins (SCOP) folds, in proteins of various origins. We further assess the structural and functional role of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a15bd7d20ea5a94c1a515cbb222a44ee
https://doi.org/10.3390/pr10112159
https://doi.org/10.3390/pr10112159
Autor:
Maxim Kondratyev, Vladimir R. Rudnev, Kirill S. Nikolsky, Alexander A. Stepanov, Denis V. Petrovsky, Liudmila I. Kulikova, Arthur T. Kopylov, Kristina A. Malsagova, Anna L. Kaysheva
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 18; Pages: 10466
Rheumatoid arthritis belongs to the group of chronic systemic autoimmune diseases characterized by the development of destructive synovitis and extra-articular manifestations. Cytokines regulate a wide range of inflammatory processes involved in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b6222acc88c6e37a8337bfe9fdc3125
https://doi.org/10.3390/ijms231810466
https://doi.org/10.3390/ijms231810466