Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Kirill S, Korolev"'
Publikováno v:
mSystems, Vol 8, Iss 4 (2023)
ABSTRACT Microbes commonly organize into communities consisting of hundreds of species involved in complex interactions with each other. 16S ribosomal RNA (16S rRNA) amplicon profiling provides snapshots that reveal the phylogenies and abundance prof
Externí odkaz:
https://doaj.org/article/36d0658680fa47eb80e55d6f1ba5e273
Autor:
Ashish B George, Kirill S Korolev
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 1, p e1010570 (2023)
Assembling optimal microbial communities is key for various applications in biofuel production, agriculture, and human health. Finding the optimal community is challenging because the number of possible communities grows exponentially with the number
Externí odkaz:
https://doaj.org/article/d4551f8ecf73400b9415ef58ae85cf66
Autor:
Mohammad I. El Mouzan, Harland S. Winter, Assad A. Assiri, Kirill S. Korolev, Ahmad A. Al Sarkhy, Scot E. Dowd, Mohammad A. Al Mofarreh, Rajita Menon
Publikováno v:
Gut Pathogens, Vol 10, Iss 1, Pp 1-10 (2018)
Abstract Background The role of microbiota in Crohn’s disease (CD) is increasingly recognized. However, most of the reports are from Western populations. Considering the possible variation from other populations, the aim of this study was to descri
Externí odkaz:
https://doaj.org/article/8eba6c4df182430c8ad2b7cf18869695
Autor:
Ana B. Pavel, Kirill S. Korolev
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Abstract Genetic alterations initiate tumors and enable the evolution of drug resistance. The pro-cancer view of mutations is however incomplete, and several studies show that mutational load can reduce tumor fitness. Given its negative effect, genet
Externí odkaz:
https://doaj.org/article/c67685747c7f4e45815ea603bf2059a7
Autor:
Feng Wang, Jess L. Kaplan, Benjamin D. Gold, Manoj K. Bhasin, Naomi L. Ward, Richard Kellermayer, Barbara S. Kirschner, Melvin B. Heyman, Scot E. Dowd, Stephen B. Cox, Haluk Dogan, Blaire Steven, George D. Ferry, Stanley A. Cohen, Robert N. Baldassano, Christopher J. Moran, Elizabeth A. Garnett, Lauren Drake, Hasan H. Otu, Leonid A. Mirny, Towia A. Libermann, Harland S. Winter, Kirill S. Korolev
Publikováno v:
Cell Reports, Vol 14, Iss 4, Pp 945-955 (2016)
The relationship between the host and its microbiota is challenging to understand because both microbial communities and their environments are highly variable. We have developed a set of techniques based on population dynamics and information theory
Externí odkaz:
https://doaj.org/article/b6608d22817740caa2ac0ab0b05f0ef1
Autor:
Ashish B George, Kirill S Korolev
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 12, p e1006645 (2018)
Chirality in shape and motility can evolve rapidly in microbes and cancer cells. To determine how chirality affects cell fitness, we developed a model of chiral growth in compact aggregates such as microbial colonies and solid tumors. Our model recap
Externí odkaz:
https://doaj.org/article/de2567e6b0764229a23a6df74b4e9ae8
A metabolic modeling platform for the computation of microbial ecosystems in time and space (COMETS)
Autor:
Michael Quintin, Ilija Dukovski, Alvaro Sanchez, Kirill S. Korolev, Daniel Segrè, Alan R. Pacheco, Djordje Bajić, Snorre Sulheim, David B. Bernstein, Jean C. C. Vila, William R. Harcombe, Jeremy M. Chacón, William J. Riehl
Publikováno v:
Nature Protocols. 16:5030-5082
Genome-scale stoichiometric modeling of metabolism has become a standard systems biology tool for modeling cellular physiology and growth. Extensions of this approach are emerging as a valuable avenue for predicting, understanding and designing micro
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 1, p e1005939 (2018)
Microbiota contribute to many dimensions of host phenotype, including disease. To link specific microbes to specific phenotypes, microbiome-wide association studies compare microbial abundances between two groups of samples. Abundance differences, ho
Externí odkaz:
https://doaj.org/article/ce8bb338b47143a593fa562b0f9ad2ba
Publikováno v:
New Journal of Physics, Vol 22, Iss 8, p 083034 (2020)
Self-activation coupled to a transport mechanism results in traveling waves that describe polymerization reactions, forest fires, tumor growth, and even the spread of epidemics. Diffusion is a simple and commonly used model of particle transport. Man
Externí odkaz:
https://doaj.org/article/f578b839755640728f9790202f691691
Autor:
Asaad A Assiri, Harland S. Winter, Kirill S. Korolev, Mohammad I. El Mouzan, Ahmed Al Sarkhy, Rajita Menon
Publikováno v:
Saudi Journal of Gastroenterology : Official Journal of the Saudi Gastroenterology Association
The Saudi Journal of Gastroenterology, Vol 27, Iss 3, Pp 144-148 (2021)
The Saudi Journal of Gastroenterology, Vol 27, Iss 3, Pp 144-148 (2021)
Background: Studies have reached different conclusions regarding the accuracy of dysbiosis in predicting the diagnosis of Crohn's disease (CD). The aim of this report is to assess the utility of mucosal and fecal microbial dysbiosis as predictors in