Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Kirby P. Gardner"'
Autor:
Ashvathi Raghavakaimal, Massimo Cristofanilli, Cha-Mei Tang, R. K. Alpaugh, Kirby P. Gardner, Saranya Chumsri, Daniel L. Adams
Publikováno v:
Breast Cancer Research, Vol 24, Iss 1, Pp 1-12 (2022)
Abstract Background CCR5 is a motility chemokine receptor implicated in tumor progression, whose activation and subsequent endocytosis may identify highly aggressive breast cancer cell subtypes likely to spread into the circulatory system. Methods Th
Externí odkaz:
https://doaj.org/article/94fb5aec576d4dde891dae15d8d153b8
Publikováno v:
npj Precision Oncology, Vol 5, Iss 1, Pp 1-7 (2021)
Abstract Pancreatic cancer (PC) is notoriously difficult to diagnosis and properly stage resulting in incorrect primary treatment. Diagnostic and prognostic biomarkers are desperately needed to more accurately stage patients and select proper treatme
Externí odkaz:
https://doaj.org/article/2584944841bc4ed8b933510f4a3fd00a
Publikováno v:
PLoS ONE, Vol 17, Iss 3 (2022)
The aggressive nature and metastatic potential of pancreatic cancer (PC) results in poor prognosis and high mortality. A better understanding of the underlying biology of PC and the ability of tumor cells to spread to distant sites is needed to advan
Externí odkaz:
https://doaj.org/article/a3a399881d2e48089911c96e03b0159e
Autor:
Dimpal M. Kasabwala, Raymond C. Bergan, Kirby P. Gardner, Rena Lapidus, Susan Tsai, Mohammed Aldakkak, Daniel L. Adams
Publikováno v:
Biomedicines, Vol 10, Iss 11, p 2898 (2022)
Micronuclei (MN) are fragments of damaged nucleic acids which budded from a cell’s nuclei as a repair mechanism for chromosomal instabilities, which within circulating white blood cells (cWBCs) signifies increased cancer risk, and in tumor cells in
Externí odkaz:
https://doaj.org/article/962e79c584dd4b62880113fa59cb014f
Autor:
Kirby P. Gardner, Massimo Cristofanilli, Saranya Chumsri, Rena Lapidus, Cha-Mei Tang, Ashvathi Raghavakaimal, Daniel L. Adams
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 13, p 7299 (2022)
The usage of beta blockers in breast cancer (BC) patients is implicated in the reduction in distant metastases, cancer recurrence, and cancer mortality. Studies suggest that the adrenergic pathway is directly involved in sympathetic-driven hematopoie
Externí odkaz:
https://doaj.org/article/7f65ac005f1247f99fdc76d3ab3cf46c
Autor:
Jillian A. Moran, Daniel L. Adams, Martin J. Edelman, Pablo Lopez, Jianzhong He, Yawei Qiao, Ting Xu, Zhongxing Liao, Kirby P. Gardner, Cha-Mei Tang, Steven H. Lin
Publikováno v:
JCO Precision Oncology.
PURPOSE Current diagnostic methods to determine programmed death 1 (PD-1) receptor and its ligand (PD-L1)/PD-1 immunotherapy (immune checkpoint inhibitor [ICI]) efficacy in recurrent or metastatic non–small-cell lung carcinoma (rmNSCLC) are impreci
Autor:
Jillian A. Moran, Steven H. Lin, Martin J. Edelman, Pablo Lopez, Jianzhong He, Yawei Qiao, Ting Xu, Zhongxing Liao, Kirby P. Gardner, Cha-Mei Tang, Daniel L. Adams
Publikováno v:
Cancer Research. 83:3310-3310
Purpose: Cancer extracellular vesicles (EVs) are involved in cellular communication, tumor growth, progression, and metastasis in cancer. The origins of EVs, their formation, and potential clinical use as biomarkers are not well understood. Recently,
Autor:
Ashvathi Raghavakaimal, Massimo Cristofanilli, Cha-Mei Tang, R. K. Alpaugh, Kirby P. Gardner, Saranya Chumsri, Daniel L. Adams
Publikováno v:
Breast cancer research : BCR. 24(1)
Background CCR5 is a motility chemokine receptor implicated in tumor progression, whose activation and subsequent endocytosis may identify highly aggressive breast cancer cell subtypes likely to spread into the circulatory system. Methods The MDA-MB-
Publikováno v:
PloS one. 17(3)
The aggressive nature and metastatic potential of pancreatic cancer (PC) results in poor prognosis and high mortality. A better understanding of the underlying biology of PC and the ability of tumor cells to spread to distant sites is needed to advan
Autor:
Daniel L. Adams, Ashvathi Raghavakaimal, Cha-Mei Tang, Kirby P. Gardner, Nitya G. Ray, Nader Pourhassan
Publikováno v:
Cancer Research. 82:CT156-CT156
Background: Metastatic triple negative breast cancer (mTNBC) is a highly invasive breast cancer subtype that has limited treatment options and poor clinical outcomes for patients. Recently, the C-C chemokine receptor 5 (CCR5) was identified in precli