Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Kirby N. Thomas"'
Autor:
Wenjun Gao, Ezekiel Gonzalez-Fernandez, Kirby N Thomas, Fan Fan, Letao Fan, Yedan Liu, Shaoxun Wang, Richard J. Roman
Publikováno v:
Physiol Genomics
Hypertension is a leading risk factor for stroke, heart disease, chronic kidney disease, vascular cognitive impairment, and Alzheimer’s disease. Previous genetic studies have nominated hundreds of genes linked to hypertension, and renal and cogniti
Autor:
Shaoxun Wang, Feng Jiao, Jane J. Border, Xing Fang, Reece F. Crumpler, Yedan Liu, Huawei Zhang, Joshua Jefferson, Ya Guo, Parker S. Elliott, Kirby N. Thomas, Luke B. Strong, Austin H. Urvina, Baoying Zheng, Arjun Rijal, Stanley V. Smith, Hongwei Yu, Richard J. Roman, Fan Fan
Publikováno v:
Am J Physiol Heart Circ Physiol
Diabetes mellitus (DM) is a leading risk factor for age-related dementia, but the mechanisms involved are not well understood. We previously discovered that hyperglycemia induced impaired myogenic response (MR) and cerebral blood flow (CBF) autoregul
Autor:
Xing Fang, Huawei Zhang, Jane J. Border, Patrice L. Rivers, Luke B. Strong, Jonita Cooper, Reece F. Crumpler, Kirby N. Thomas, Richard J. Roman, Fan Fan
Publikováno v:
The FASEB Journal. 36
Publikováno v:
Physiology international.
Cognitive impairment and dementia are significant health burdens worldwide. Aging, hypertension, and diabetes are the primary risk factors for Alzheimer’s disease and Alzheimer’s disease and related dementias (AD/ADRD). There are no effective tre
Autor:
Shaoxun Wang, Jane J Ryu, Luke B Strong, Yedan Liu, Baoying Zheng, Richard J. Roman, Reese F Crumpler, Huawei Zhang, Kirby N Thomas, Fan Fan, Xing Fang, Parker S Elliott
Publikováno v:
Hypertension. 78
We have previously identified an inactivating mutation of ADD3 in FHH rats which is associated with impaired myogenic reactivity of renal arterioles and podocyte function, and contributes to the development of CKD. We have found that SNPs in human AD
Autor:
Reece F Crumpler, Fan Fan, Jane J Ryu, Xing Fang, Shaoxun Wang, Luke B Strong, Parker S Elliot, Richard J. Roman, Baoying Zheng, Kirby N Thomas, Huawei Zhang
Publikováno v:
Hypertension. 78
20-HETE is synthesized from arachidonic acid by cytochrome P450 (CYP) enzymes 4A and 4F. Inactivating mutations in the CYP enzymes that produce 20-HETE are associated with hypertension and stroke in man. We previously revealed that inactivating varia