Zobrazeno 1 - 10
of 2 479
pro vyhledávání: '"Kirby D"'
Autor:
Xiaoli Ye, Yuanyuan Li, Domingo González-Lamuño, Zhengtong Pei, Ann B. Moser, Kirby D. Smith, Paul A. Watkins
Publikováno v:
Cells, Vol 13, Iss 20, p 1687 (2024)
“Bubblegum” acyl-CoA synthetase (ACSBG1) is a pivotal player in lipid metabolism during mouse brain development, facilitating the activation of long-chain fatty acids (LCFA) and their incorporation into lipid species that are crucial for brain fu
Externí odkaz:
https://doaj.org/article/af92b82d09844b3baa4523893b94d89f
Publikováno v:
Frontiers in Human Neuroscience, Vol 17 (2023)
Strong cognitive regulation is advantageous for flexible, responsive parenting. Optimal cognitive regulation is reliant on associations between physiological mechanisms of central and peripheral nervous system functioning. Across middle adulthood the
Externí odkaz:
https://doaj.org/article/4debe108c8d34e59ac978902c4775dad
Autor:
Mabel Minji Jung, Siqi Shen, Giovanni A. Botten, Thomas Olender, Koichi R. Katsumura, Kirby D. Johnson, Alexandra A. Soukup, Peng Liu, Qingzhou Zhang, Zena D. Jensvold, Peter W. Lewis, Robert A. Beagrie, Jason K.K. Low, Lihua Yang, Joel P. Mackay, Lucy A. Godley, Marjorie Brand, Jian Xu, Sunduz Keles, Emery H. Bresnick
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 7 (2023)
Although certain human genetic variants are conspicuously loss of function, decoding the impact of many variants is challenging. Previously, we described a patient with leukemia predisposition syndrome (GATA2 deficiency) with a germline GATA2 variant
Externí odkaz:
https://doaj.org/article/0a1d39017eb14888912ea7fe69a08151
Autor:
Vu L. Tran, Peng Liu, Koichi R. Katsumura, Erin Kim, Bjorn M. Schoff, Kirby D. Johnson, Emery H. Bresnick
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106297- (2023)
Summary: Innate immune signaling protects against pathogens, controls hematopoietic development, and functions in oncogenesis, yet the relationship between these mechanisms is undefined. Downregulating the GATA2 transcription factor in fetal hematopo
Externí odkaz:
https://doaj.org/article/5f3b08aa83854df7811358f16b3aa550
Autor:
Kelsi N. Singer, Oliver L. White, Bernard Schmitt, Erika L. Rader, Silvia Protopapa, William M. Grundy, Dale P. Cruikshank, Tanguy Bertrand, Paul M. Schenk, William B. McKinnon, S. Alan Stern, Rajani D. Dhingra, Kirby D. Runyon, Ross A. Beyer, Veronica J. Bray, Cristina Dalle Ore, John R. Spencer, Jeffrey M. Moore, Francis Nimmo, James T. Keane, Leslie A. Young, Catherine B. Olkin, Tod R. Lauer, Harold A. Weaver, Kimberly Ennico-Smith
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
Giant icy volcanos (cryovolcanos) on Pluto are unique in the imaged solar system and provide evidence for unexpected, active geology late in Pluto’s history.
Externí odkaz:
https://doaj.org/article/425159a9207e45579adf4ca50dc43b28
Autor:
Joshua A. Krachman, Jessica A. Patricoski, Christopher T. Le, Jina Park, Ruijing Zhang, Kirby D. Gong, Indranuj Gangan, Raimond L. Winslow, Joseph L. Greenstein, James Fackler, Anthony A. Sochet, Jules P. Bergmann
Publikováno v:
Frontiers in Pediatrics, Vol 9 (2021)
Background: High flow nasal cannula (HFNC) is commonly used as non-invasive respiratory support in critically ill children. There are limited data to inform consensus on optimal device parameters, determinants of successful patient response, and indi
Externí odkaz:
https://doaj.org/article/936a3e40619c4397af3d8200c68880d5
Autor:
Emery H. Bresnick, Kirby D. Johnson
Publikováno v:
Blood Advances, Vol 3, Iss 13, Pp 2045-2056 (2019)
Abstract: Intensive scrutiny of human genomes has unveiled considerable genetic variation in coding and noncoding regions. In cancers, including those of the hematopoietic system, genomic instability amplifies the complexity and functional consequenc
Externí odkaz:
https://doaj.org/article/2098c9d956cc40e09af1bef20ba31a55
Autor:
Paul M. Schenk, Chloe B. Beddingfield, Tanguy Bertrand, Carver Bierson, Ross Beyer, Veronica J. Bray, Dale Cruikshank, William M. Grundy, Candice Hansen, Jason Hofgartner, Emily Martin, William B. McKinnon, Jeffrey M. Moore, Stuart Robbins, Kirby D. Runyon, Kelsi N. Singer, John Spencer, S. Alan Stern, Ted Stryk
Publikováno v:
Remote Sensing, Vol 13, Iss 17, p 3476 (2021)
The topography of Neptune’s large icy moon Triton could reveal important clues to its internal evolution, but has been difficult to determine. New global digital color maps for Triton have been produced as well as topographic data for
Externí odkaz:
https://doaj.org/article/3c80aa6d2efb4e57825304179bbb0be4
Autor:
Charu Mehta, Kirby D. Johnson, Xin Gao, Irene M. Ong, Koichi R. Katsumura, Skye C. McIver, Erik A. Ranheim, Emery H. Bresnick
Publikováno v:
Cell Reports, Vol 20, Iss 12, Pp 2966-2979 (2017)
Hematopoietic development requires the transcription factor GATA-2, and GATA-2 mutations cause diverse pathologies, including leukemia. GATA-2-regulated enhancers increase Gata2 expression in hematopoietic stem/progenitor cells and control hematopoie
Externí odkaz:
https://doaj.org/article/5f5db142b9614d63809ec53cb53732d3
Publikováno v:
Frontiers in Aging Neuroscience, Vol 11 (2019)
Down syndrome (DS), a genetic disorder caused by partial or complete triplication of chromosome 21, is the most common genetic cause of intellectual disability. DS mouse models and cell lines display defects in cellular adaptive stress responses incl
Externí odkaz:
https://doaj.org/article/4afa015220ff4a13aa5f59cad516a368