Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Kirandeep Dhami"'
Autor:
Jie Xiang, Denis A. Malyshev, Jörg Zimmermann, Kirandeep Dhami, Li Zhengtao, Thomas Lavergne, Floyd E. Romesberg, Ramkrishna Adhikary, Phillip Ordoukhanian, Zhelin Sun
Publikováno v:
Chemistry - A European Journal. 19:14205-14209
A class of replicable unnatural DNA base pairs formed between d5SICS and either dMMO2, dDMO, or dNaM were developed. To explore the use of these pairs to produce site-specifically labeled DNA, the synthesis of a variety of derivatives bearing propyny
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a66991d5e0ab692a80e55132ac519299
https://doi.org/10.1002/chem.201302496
https://doi.org/10.1002/chem.201302496
Autor:
Michal Hocek, Phillip Ordoukhanian, Denis A. Malyshev, Tomáš Kubelka, Kirandeep Dhami, Floyd E. Romesberg
Publikováno v:
Nucleic Acids Research
We have developed a family of unnatural base pairs (UBPs), which rely on hydrophobic and packing interactions for pairing and which are well replicated and transcribed. While the pair formed between d5SICS and dNaM (d5SICS-dNaM) has received the most
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::642c6caa3a3adb49c46edd73321ba06f
https://pubmed.ncbi.nlm.nih.gov/25122747
https://pubmed.ncbi.nlm.nih.gov/25122747
Autor:
Tingjian Chen, Jeremy M. Foster, Ivan R. Corrêa, Denis A. Malyshev, Floyd E. Romesberg, Nan Dai, Thomas Lavergne, Kirandeep Dhami
Publikováno v:
Nature. 509(7500)
Organisms are defined by the information encoded in their genomes, and since the origin of life this information has been encoded using a two-base-pair genetic alphabet (A-T and G-C). In vitro, the alphabet has been expanded to include several unnatu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbdc725f14dfa36a2b71c4c2aa0f6e63
https://pubmed.ncbi.nlm.nih.gov/24840551
https://pubmed.ncbi.nlm.nih.gov/24840551
Autor:
Floyd E. Romesberg, Kirandeep Dhami, Thomas Lavergne, Denis A. Malyshev, Lingjun Li, Phillip Ordoukhanian, Melissa Degardin
We synthesized a panel of unnatural base pairs whose pairing depends on hydrophobic and packing forces and identify dTPT3-dNaM, which is PCR amplified with a natural base pair-like efficiency and fidelity. In addition, the dTPT3 scaffold is uniquely
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b573ceebc46d0c331587acf6b9c245f
https://europepmc.org/articles/PMC3979842/
https://europepmc.org/articles/PMC3979842/
Autor:
Kirandeep Dhami, Thomas Lavergne, Floyd E. Romesberg, Henry T. Quach, Phillip Ordoukhanian, Denis A. Malyshev, Melissa Degardin
As part of an ongoing effort to expand the genetic alphabet for in vitro and eventually in vivo applications, we have synthesized a wide variety of predominantly hydrophobic unnatural base pairs exemplified by d5SICS-dMMO2 and d5SICS-dNaM. When incor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ad0381d29d7ca4c19bb0a253092de56
https://europepmc.org/articles/PMC3690937/
https://europepmc.org/articles/PMC3690937/
Autor:
Ali Torkamani, Thomas Lavergne, Henry T. Quach, Kirandeep Dhami, Floyd E. Romesberg, Denis A. Malyshev, Phillip Ordoukhanian
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 109(30)
The natural four-letter genetic alphabet, comprised of just two base pairs (dA-dT and dG-dC), is conserved throughout all life, and its expansion by the development of a third, unnatural base pair has emerged as a central goal of chemical and synthet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::910281794d10e0ec209a2751cc353987
https://pubmed.ncbi.nlm.nih.gov/22773812
https://pubmed.ncbi.nlm.nih.gov/22773812