Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Kiran Yanamandra"'
Autor:
Justine D. Manos, Christina N. Preiss, Nandini Venkat, Joseph Tamm, Peter Reinhardt, Taekyung Kwon, Jessica Wu, Allison D. Winter, Thomas R. Jahn, Kiran Yanamandra, Katherine Titterton, Eric Karran, Xavier Langlois
Publikováno v:
iScience, Vol 25, Iss 1, Pp 103658- (2022)
Summary: Tau pathobiology has emerged as a key component underlying Alzheimer's disease (AD) progression; however, human neuronal in vitro models have struggled to recapitulate tau phenomena observed in vivo. Here, we aimed to define the minimal requ
Externí odkaz:
https://doaj.org/article/404fbb380b7c40598ab18adb2b081dcc
Autor:
Satoshi Muraoka, Mark P. Jedrychowski, Kiran Yanamandra, Seiko Ikezu, Steven P. Gygi, Tsuneya Ikezu
Publikováno v:
Cells, Vol 9, Iss 9, p 1959 (2020)
Pathological hallmarks of Alzheimer’s disease (AD) are deposits of amyloid beta (Aβ) and hyper-phosphorylated tau aggregates in brain plaques. Recent studies have highlighted the importance of Aβ and tau-containing extracellular vesicles (EVs) in
Externí odkaz:
https://doaj.org/article/4d739c8a28f34d1b8fa851613e4ab023
Autor:
Kiran Yanamandra, Marina A Gruden, Vida Casaite, Rolandas Meskys, Lars Forsgren, Ludmilla A Morozova-Roche
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18513 (2011)
BackgroundAuto-antibodies with specificity to self-antigens have been implicated in a wide variety of neurological diseases, including Parkinson's (PD) and Alzheimer's diseases, being sensitive indicators of neurodegeneration and focus for disease pr
Externí odkaz:
https://doaj.org/article/425dcc581af64191a9babe7e6ae37378
Autor:
Kiran Yanamandra, Oleg Alexeyev, Vladimir Zamotin, Vaibhav Srivastava, Andrei Shchukarev, Ann-Christin Brorsson, Gian Gaetano Tartaglia, Thomas Vogl, Rakez Kayed, Gunnar Wingsle, Jan Olsson, Christopher M Dobson, Anders Bergh, Fredrik Elgh, Ludmilla A Morozova-Roche
Publikováno v:
PLoS ONE, Vol 4, Iss 5, p e5562 (2009)
BACKGROUND:The conversion of soluble peptides and proteins into polymeric amyloid structures is a hallmark of many age-related degenerative disorders, including Alzheimer's disease, type II diabetes and a variety of systemic amyloidoses. We report he
Externí odkaz:
https://doaj.org/article/9d7ef73e60f04cd6b63b0882068677f5
Autor:
Taekyung Kwon, Gen Lin, Sarah E. Chancellor, Astrid Wachter, Aicha Abdourahman, Rachel E Bennett, Fan Liao, Timothy Pastika, Joseph A. Tamm, Nandini Venkat, Kiran Yanamandra, Yelena Grinberg, Markus P. Kummer, Sudeshna Das, Tammy L. Dellovade, Eric H Karran, Robert V. Talanian, Knut Biber, Janina S Ried, Alberto Serrano‐Pozo, Xavier Langlois, Bradley T. Hyman
Publikováno v:
Alzheimer's & Dementia. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7faab0989676e26512a0cff02386df3a
https://doi.org/10.1002/alz.063430
https://doi.org/10.1002/alz.063430
Autor:
Mark P. Jedrychowski, Tsuneya Ikezu, Satoshi Muraoka, Steven P. Gygi, Kiran Yanamandra, Seiko Ikezu
Publikováno v:
Cells
Cells, Vol 9, Iss 1959, p 1959 (2020)
Volume 9
Issue 9
Cells, Vol 9, Iss 1959, p 1959 (2020)
Volume 9
Issue 9
Pathological hallmarks of Alzheimer&rsquo
s disease (AD) are deposits of amyloid beta (A&beta
) and hyper-phosphorylated tau aggregates in brain plaques. Recent studies have highlighted the importance of A&beta
and tau-containing extra
s disease (AD) are deposits of amyloid beta (A&beta
) and hyper-phosphorylated tau aggregates in brain plaques. Recent studies have highlighted the importance of A&beta
and tau-containing extra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdafdb1f95cc07814fd3c7eeaedd6447
http://europepmc.org/articles/PMC7565882
http://europepmc.org/articles/PMC7565882
Autor:
Susan E. Maloney, David F. Wozniak, Thomas E. Mahan, Marc I. Diamond, David M. Holtzman, Hong Jiang, Kiran Yanamandra
Publikováno v:
Annals of Clinical and Translational Neurology
Objective We previously found a strong reduction in tau pathology and insoluble tau in P301S tau transgenic mice following intracerebroventricular infusion of the anti-tau antibody HJ8.5. We sought to determine the effects of HJ8.5 in the same model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6ce720abe977618e8555f0d3ab49c2c
https://doi.org/10.1002/acn3.176
https://doi.org/10.1002/acn3.176
Autor:
Robert David Edmund Sewell, Marina A. Gruden, Tatiana V. Davidova, Valery G. Kucheryanu, Kiran Yanamandra, Vladimir V. Sherstnev, Ludmilla A. Morozova-Roche
Publikováno v:
Behavioural Brain Research. 243:205-212
Animal models of Parkinson's disease (PD) have been widely used to investigate the pathogenesis of this neurodegenerative disorder which is typically associated with the specific and largely disordered protein α-synuclein (α-syn). In the current st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7de8564036e47ac894a2f8a64d5eca4f
https://doi.org/10.1016/j.bbr.2013.01.011
https://doi.org/10.1016/j.bbr.2013.01.011
Autor:
Günter Fritz, Ludmilla A. Morozova-Roche, Kiran Yanamandra, Sónia S. Leal, Hugo M. Botelho, Cláudio M. Gomes, Isabel Cardoso
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
S100A6 is a small EF-hand calcium- and zinc-binding protein involved in the regulation of cell proliferation and cytoskeletal dynamics. It is overexpressed in neurodegenerative disorders and a proposed marker for Amyotrophic Lateral Sclerosis (ALS).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cad50d7fa77f8ffa1e6fd90b5cbdbee2
https://doi.org/10.1074/jbc.m112.396416
https://doi.org/10.1074/jbc.m112.396416
Publikováno v:
Methods in Pharmacology and Toxicology ISBN: 9781493935581
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06091ca31ddb4055621b806063fee711
https://doi.org/10.1007/978-1-4939-3560-4_9
https://doi.org/10.1007/978-1-4939-3560-4_9
