Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Kiran Chada"'
Publikováno v:
iScience, Vol 24, Iss 7, Pp 102684- (2021)
Summary: Tuberous sclerosis (TS) is a rare disorder exhibiting multi-systemic benign neoplasms. We hypothesized the origin of TS neoplastic cells derived from the neural crest given the heterogeneous ecto-mesenchymal phenotype of the most common TS n
Externí odkaz:
https://doaj.org/article/bff177c25efa4784a8a4c444d8d9c04b
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 9, p 3151 (2020)
High mobility group AT-hook 2 (HMGA2) has been associated with increased cell proliferation and cell cycle dysregulation, leading to the ontogeny of varied tumor types and their metastatic potentials, a frequently used index of disease prognosis. In
Externí odkaz:
https://doaj.org/article/cae0d2de7199405aa4b3b85dff717bd0
Autor:
Uchenna Unachukwu, Jarrod Sonett, Denzel Woode, Takayuki Shiomi, Kiran Chada, Jeanine M. D'Armiento
Publikováno v:
Molecular Cancer Therapeutics.
Tuberous Sclerosis Complex (TSC) tumors are presently incurable despite a cytostatic response to mTOR pathway inhibition since recurrence of disease occurs after discontinuation of treatment. Here, we explored the hypothesis that inhibiting tyrosine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e4faad968d5ea7b36bab80f46e1060c
https://doi.org/10.1158/1535-7163.mct-22-0224
https://doi.org/10.1158/1535-7163.mct-22-0224
Autor:
Kiran Chada, Jeanine D'Armiento, Yasunori Okada, Matthias Szabolcs, Devipriya Sankarasharma, Akira Mitoro, M. Raza Zaidi, Asahiro Morishita
Supplementary Figure 10 - PDF file 84K, HMGA2 mRNA expression in MCF7 and MDA-MB231 human breast cancer cells treated with TGFBeta 1 as detected by qRT-PCR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52eccb3c707e0611213ef64dd8398849
https://doi.org/10.1158/0008-5472.22395093
https://doi.org/10.1158/0008-5472.22395093
Autor:
Kiran Chada, Devipriya Sankarasharma, Patrick Geraghty, Sarah Marks, Takayuki Shiomi, Jeanine D'Armiento
Legend for Supplemental Figures S1-S2.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28915d8b6b775f643e78f7fe0b7e7ccb
https://doi.org/10.1158/0008-5472.22409159.v1
https://doi.org/10.1158/0008-5472.22409159.v1
Autor:
Kiran Chada, Jeanine D'Armiento, Yasunori Okada, Matthias Szabolcs, Devipriya Sankarasharma, Akira Mitoro, M. Raza Zaidi, Asahiro Morishita
Supplementary Figure 6 - PDF file 132K, (A) HMGA2 was detected at the edge of the metastatic lung tumor (left, arrows) and from the vessel of the liver stroma to the parenchyma in the metastatic liver tumor (right, arrows). Scale bars represent 100 m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21d2264bc6e43eea1bdeb07d6644be65
https://doi.org/10.1158/0008-5472.22395075
https://doi.org/10.1158/0008-5472.22395075
Autor:
Kiran Chada, Devipriya Sankarasharma, Patrick Geraghty, Sarah Marks, Takayuki Shiomi, Jeanine D'Armiento
Tuberin is present in all Tsc2+/- mesenchymal tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::125e4b56daaa232702e2311d5fb93c3a
https://doi.org/10.1158/0008-5472.22409153
https://doi.org/10.1158/0008-5472.22409153
Autor:
Kiran Chada, Devipriya Sankarasharma, Patrick Geraghty, Sarah Marks, Takayuki Shiomi, Jeanine D'Armiento
Tsc2+/- extra-renal tumorigenesis is HMGA2 dependent (S1); Summary of human AML LOH analysis (S2).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08bed3a85505714c0323c9e480a90825
https://doi.org/10.1158/0008-5472.22409150.v1
https://doi.org/10.1158/0008-5472.22409150.v1
Autor:
Kiran Chada, Jeanine D'Armiento, Yasunori Okada, Matthias Szabolcs, Devipriya Sankarasharma, Akira Mitoro, M. Raza Zaidi, Asahiro Morishita
Supplementary Figure 3 - PDF file 171K, Immunofluorescence analysis of ZEB1 (left), Fibronectin (right) expression in MCF7-Mock and MCF7-HMGA2 cells. Scale bars represent 50 microm. ZEB1 and fibronectin are expressed in the nucleus of MCF7-HMGA2 cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::054a081a0e68741380dcc3c4e77f6821
https://doi.org/10.1158/0008-5472.22395087.v1
https://doi.org/10.1158/0008-5472.22395087.v1
Autor:
Kiran Chada, Jeanine D'Armiento, Yasunori Okada, Matthias Szabolcs, Devipriya Sankarasharma, Akira Mitoro, M. Raza Zaidi, Asahiro Morishita
Supplementary Figure 2 - PDF file 77K, Agarose Colony Formation Assay. Anchorage-independent proliferation was performed by plating SW403, HT29, SW620, SW480 and HCT116 (1000 cells per well) in six-well plates, with a bottom layer of 0.6% agar and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75ee005b3aa86ea19ac35a24c6aac4ee
https://doi.org/10.1158/0008-5472.22395090
https://doi.org/10.1158/0008-5472.22395090