Zobrazeno 1 - 10 of 23 pro vyhledávání: '"Kiran, Maan"'
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Akademický článek
Metabolomics and transcriptomics based multi-omics integration reveals radiation-induced altered pathway networking and underlying mechanism
Autor: Kiran Maan, Ruchi Baghel, Seema Dhariwal, Apoorva Sharma, Radhika Bakhshi, Poonam Rana
Publikováno v: npj Systems Biology and Applications, Vol 9, Iss 1, Pp 1-13 (2023)
Abstract Recent advancement in integrated multi-omics has significantly contributed to many areas of the biomedical field. Radiation research has also grasped uprising omics technologies in biomarker identification to aid in triage management. Herein
Externí odkaz: https://doaj.org/article/e01552dd3f7444f4a4cc9afa5fa080cc
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3
An integrative chemometric approach and correlative metabolite networking of LC-MS and 1H NMR based urine metabolomics for radiation signatures
Autor: Kiran Maan, Ruchi Baghel, Radhika Bakhshi, Seema Dhariwal, Ritu Tyagi, Poonam Rana
Publikováno v: Molecular Omics. 18:214-225
A comprehensive overview of combining data from LC-MS and NMR using multiblock-OPLSDA analysis, correlation networking and pathway enrichment. This provided novel avenues for understanding biological perturbations post radiation injury.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b947981378eaadf1fef2c210586d7730
https://doi.org/10.1039/d1mo00399b
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4
Systematic untargeted UHPLC-Q-TOF-MS based lipidomics workflow for improvised detection and annotation of lipid sub-classes in serum
Autor: Poonam Rana, Seema Dhariwal, Kiran Maan, Ruchi Baghel, Apoorva Sharma, Dipankar Malakar
Selection of best approach for detection, annotation, and throughput for lipidomics of biofluids is still complicated. To maximize the lipid detection, serum lipid profiling was performed on CSH-C18 and EVO-C18 column. The different column chemistrie
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9a03f1acd4b0a52114ae1c2c6df0e349
https://doi.org/10.21203/rs.3.rs-1642090/v1
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5
Urine metabolomics based prediction model approach for radiation exposure
Autor: Poonam Rana, Kiran Maan, Ritu Tyagi, Subash Khushu
Publikováno v: Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
The radiological incidents and terrorism have demanded the need for the development of rapid, precise, and non-invasive technique for detection and quantification of exposed dose of radiation. Though radiation induced metabolic markers have been thor
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dfaa1def4a8a0d6dc349afc0a78c85a
http://link.springer.com/article/10.1038/s41598-020-72426-4
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8
Comparative metabolic profiles of total and partial body radiation exposure in mice using an untargeted metabolomics approach
Autor: Ajaswrata Dutta, Ritu Tyagi, Kiran Maan, Radhika Bakhshi, Poonam Rana
Publikováno v: Metabolomics. 16
A large scale population exposure to ionizing radiation during intentional or unintentional nuclear accidents undoubtedly generates a complex scenario with partial-body as well as total-body irradiated victims. A high throughput technique based rapid
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::719420ac607dd296b6dbb5a6c70fc13f
https://doi.org/10.1007/s11306-020-01742-7
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9
Comparative metabolic profiles of total and partial body radiation exposure in mice using an untargeted metabolomics approach
Autor: Kiran, Maan, Ritu, Tyagi, Ajaswrata, Dutta, Radhika, Bakhshi, Poonam, Rana
Publikováno v: Metabolomics : Official journal of the Metabolomic Society. 16(12)
A large scale population exposure to ionizing radiation during intentional or unintentional nuclear accidents undoubtedly generates a complex scenario with partial-body as well as total-body irradiated victims. A high throughput technique based rapid
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::cd4df5f23aa1655c273513733cbc088a
https://pubmed.ncbi.nlm.nih.gov/33245511
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10
Trichostatin A, an epigenetic modifier, mitigates radiation-induced androphysiological anomalies and metabolite changes in mice as evident from NMR-based metabolomics
Autor: Poonam Rana, Teena Haritwal, Paban K. Agrawala, Ajay Kumar Singh, Subash Khushu, Kiran Maan, Suhel Parvez
Publikováno v: International journal of radiation biology. 95(4)
Ionizing radiation is known to damage male reproductive system. Current study aims to study the mitigative effects of trichostatin A on male reproductive system and accompanying metabolite changes in testicular tissue of mice.Eight-week-old male C57
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e20e7a1c534cf14d02cca8310b52a427
https://pubmed.ncbi.nlm.nih.gov/30307353
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