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pro vyhledávání: '"Kira Steigerwald"'
Autor:
Gregory K. Behbehani, Andrew M. Lowy, Joanna Groden, Michelle Craig Barton, Jiang Qian, Kelly A. Combs, Jeremy Keirsey, Amod A. Sarnaik, Tera M. Bonney, Samir Acharya, Kira Steigerwald
Publikováno v:
Gastroenterology. 135:152-162
Background & Aims: The APC tumor suppressor is well known for its ability to regulate Wnt signaling through mediation of β-catenin levels in the cell. Transient over expression of the tumor suppressor gene APC in colon cancer cells prevents entry in
Publikováno v:
Molecular cancer research : MCR. 3(2)
The APC tumor suppressor is found in nonproliferating epithelial cells of the colonic crypts and is mutated in most colorectal tumors. To understand the function of APC in normal epithelium and how its loss leads to tumor formation, we tested whether
Autor:
Marianne Hall-Angerås, Josef E. Fischer, James V. Tricoli, David F. Wieczorek, Per-Olof Hasselgren, Ulf Angerås, Kira Steigerwald
Publikováno v:
Life sciences. 49(10)
The influence of sepsis on transcription of myofibrillar proteins in skeletal muscle was studied in rats. Sepsis was induced by cecal ligation and puncture (CLP); control rats were sham-operated. Sixteen hours later, muscle levels of mRNA for myofibr