Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kira Rehn"'
Autor:
Tetsuo Shoda, Kenneth M. Kaufman, Ting Wen, Julie M. Caldwell, Garrett A. Osswald, Pathre Purnima, Nives Zimmermann, Margaret H. Collins, Kira Rehn, Heather Foote, Michael D. Eby, Wenying Zhang, Netali Ben-Baruch Morgenstern, Adina Y. Ballaban, Jeff E. Habel, Leah C. Kottyan, J. Pablo Abonia, Vincent A. Mukkada, Philip E. Putnam, Lisa J. Martin, Marc E. Rothenberg
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Eosinophilic esophagitis (EoE) is a chronic allergic inflammatory disease with a complex underlying genetic etiology. Here, the authors identify a series of rare variants in DSP and PPL in multiplex families with EoE and uncover a pathogenic role for
Externí odkaz:
https://doaj.org/article/f2e541c35dcb4834913ac2dfae852b00
Autor:
Vincent A. Mukkada, Marc E. Rothenberg, J. Pablo Abonia, Pathre Purnima, Nives Zimmermann, Garrett A. Osswald, Kenneth M. Kaufman, Heather Foote, Philip E. Putnam, Michael D. Eby, Jeff E. Habel, Lisa J. Martin, Tetsuo Shoda, Kira Rehn, Wenying Zhang, Adina Y. Ballaban, Leah C. Kottyan, Margaret H. Collins, Netali Ben-Baruch Morgenstern, Julie M. Caldwell, Ting Wen
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications
Nature Communications
Eosinophilic esophagitis (EoE) is a chronic allergic inflammatory disease with a complex underlying genetic etiology. Herein, we conduct whole-exome sequencing of a multigeneration EoE pedigree (discovery set) and 61 additional multiplex families wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e7f75dea17ce67d6ee21622680158ff
https://doi.org/10.1038/s41467-021-26939-9
https://doi.org/10.1038/s41467-021-26939-9
Autor:
Wasim Ahmad, Joshua D. Smith, Jay Shendure, Regie Lyn P. Santos-Cortez, Saima Riazuddin, Deborah A. Nickerson, Kwanghyuk Lee, Muhammad Ansar, Muhammad Amin-ud-din, Arnaud P. J. Giese, Suzanne M. Leal, Abdul Aziz, Raja Hussain Ali, Kira Rehn, Xin Wang, Ilene Chiu, Michael J. Bamshad, Zubair M. Ahmed
Publikováno v:
Human Molecular Genetics. 23:3289-3298
Cyclic AMP (cAMP) production, which is important for mechanotransduction within the inner ear, is catalyzed by adenylate cyclases (AC). However, knowledge of the role of ACs in hearing is limited. Previously, a novel autosomal recessive non-syndromic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5182ed67b00888e7f565bfdabf437bae
https://doi.org/10.1093/hmg/ddu042
https://doi.org/10.1093/hmg/ddu042
Autor:
Kuan Shen Wong, Vikram Kohli, Saulius Sumanas, Juli D. Uhl, Wynn G. Hunter, Sharina Palencia-Desai, Megan S. Rost, Kira Rehn
Publikováno v:
Developmental Biology. 361(2):377-391
Endocardial cells form the inner endothelial layer of the heart tube, surrounded by the myocardium. Signaling pathways that regulate endocardial cell specification and differentiation are largely unknown and the origin of endocardial progenitors is s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8dace6ad7f3b73a95f7aa6520c1ee33
Autor:
Yui-Hsi Wang, Jaclyn W. McAlees, Gurjit K. Khurana Hershey, Ramakrishna Edukulla, Ian P. Lewkowich, Kira Rehn, Bo Liu, Andrew W. Lindsley
Publikováno v:
Immunity, Inflammation and Disease
Introduction Ceramide is the central substrate of sphingolipid metabolism and plays a key role in cellular signal transduction pathways, regulating apoptosis, differentiation, and chemotaxis. Alterations in airway ceramide levels are observed in mult
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d873f359a1a357cd6d9afa58c129e24
https://pubmed.ncbi.nlm.nih.gov/27621809
https://pubmed.ncbi.nlm.nih.gov/27621809
Publikováno v:
Journal of Visualized Experiments : JoVE
The ability to differentially label single cells has important implications in developmental biology. For instance, determining how hematopoietic, lymphatic, and blood vessel lineages arise in developing embryos requires fate mapping and lineage trac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c63e1a0409095251fd3c3ca78ca5032
https://doi.org/10.3791/3172-v
https://doi.org/10.3791/3172-v
Publikováno v:
The International journal of developmental biology. 55(6)
Aquaporin 1 (Aqp1) is a water channel protein, expressed widely in microvascular endothelial cells and implicated in mammalian tumor angiogenesis. However, its developmental expression has not yet been characterized in great detail. An enhancer trap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db5bdff603bd327013b30eb7dcf939d8
https://pubmed.ncbi.nlm.nih.gov/21948709
https://pubmed.ncbi.nlm.nih.gov/21948709