Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kira Misura"'
The eptinezumab:CGRP complex structure – the role of conformational changes in binding stabilization
Publikováno v:
Bioengineered
article-version (VoR) Version of Record
Bioengineered, Vol 12, Iss 2, Pp 11076-11086 (2021)
article-version (VoR) Version of Record
Bioengineered, Vol 12, Iss 2, Pp 11076-11086 (2021)
To further elucidate the mechanism of action and binding properties of eptinezumab to calcitonin gene-related peptide (CGRP), X-ray crystallography, computational alanine scanning, and molecular dynamics were used. X-ray diffraction data were collect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6d1cc402c5c42c2f412f6bee06148d1
https://doi.org/10.1080/21655979.2021.2006977
https://doi.org/10.1080/21655979.2021.2006977
Autor:
Robert W Sandrock, Oliver Homann, Edwin Lamas, Paul Nelson, Kira Misura, Lynn E. DeLisi, Stefan I. McDonough
Publikováno v:
Molecular psychiatry
A current focus in psychiatric genetics is detection of multiple common risk alleles through very large genome-wide association study analyses. Yet families do exist, albeit rare, that have multiple affected members who are presumed to have a similar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::952e065a8640fff522af75024e1ea284
http://europepmc.org/articles/PMC5033653
http://europepmc.org/articles/PMC5033653
Autor:
Sharon Wannberg, James B. Rottman, Sabine S. Escobar, Joel Tocker, Daniela Metz, Michael R. Comeau, Deanna Mohn, Kira Misura, Alison L. Budelsky, Anh Leith, Erika Rickel, Lori Siegel, John K. Sullivan, Cynthia R. Willis
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 53:810-821
Asthma is a heterogeneous disease characterized by airway inflammation and hyperreactivity. IL-17 receptor A (IL-17RA) is a shared receptor subunit required for activity of IL-17 family cytokines, including IL-17A and IL-25. IL-17A and IL-25 induce d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78763ed5ddd89dd9cd34f2e246eb178f
https://doi.org/10.1165/rcmb.2015-0038oc
https://doi.org/10.1165/rcmb.2015-0038oc
Autor:
Steven F. Ziegler, Kaitlyn A Barrow, Andrew R. Parker, Jason S. Debley, Teal S. Hallstrand, Richard G. James, Kira Misura, Elizabeth Whalen, Stephen R. Reeves, Matthew C. Altman
Publikováno v:
The Journal of allergy and clinical immunology. 142(2)
BACKGROUND: Respiratory viral infection in early childhood, including that from respiratory syncytial virus (RSV), has been previously associated with the development of asthma. OBJECTIVE: We aimed to determine whether ex vivo RSV infection of bronch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bb2e2e93b7a30ddb127f955c4bcf636
https://pubmed.ncbi.nlm.nih.gov/29106997
https://pubmed.ncbi.nlm.nih.gov/29106997
Autor:
Jason S. Debley, Stephen R. Reeves, Teal S. Hallstrand, Andrew R. Parker, Matthew C. Altman, Tessa K. Kolstad, Michael R. Comeau, Kira Misura, Elizabeth Whalen, Steven F. Ziegler
Publikováno v:
Journal of Allergy and Clinical Immunology. 139:AB267
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77919520406c112cacd8227efd859829
https://doi.org/10.1016/j.jaci.2016.12.861
https://doi.org/10.1016/j.jaci.2016.12.861
Autor:
John C. Castle, Christopher D. Armour, Kira Misura, Christopher K. Raymond, Stuart Jackson, Matthew Biery, Carol A. Rohl, Jason M. Johnson, Ronghua Chen, Tao Xie, Heather Bouzek
Publikováno v:
BMC Genomics
BMC Genomics, Vol 11, Iss 1, p 244 (2010)
BMC Genomics, Vol 11, Iss 1, p 244 (2010)
Background DNA copy number variations occur within populations and aberrations can cause disease. We sought to develop an improved lab-automatable, cost-efficient, accurate platform to profile DNA copy number. Results We developed a sequencing-based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e21c182c9169eb0060712e92650502b1
https://pubmed.ncbi.nlm.nih.gov/20398377
https://pubmed.ncbi.nlm.nih.gov/20398377
Autor:
Thu H.M. Nguyen, Kira Misura, Wayne Tsuji, Christopher Thor, Jason Wall, Lisa A. Simms, Gareth Price, Antony Symons, Chris B. Russell, Jennifer E. Towne, Ning Huang, William A. Rees, Deon J. Venter, Graham L. Radford-Smith, Nicole M. Walker, Kathryn J. Newhall, Renee Gallagher, Richard Hu
Publikováno v:
Gastroenterology. 144:S-318
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02a5f7d4705f0c69f0722c3c7104174a
https://doi.org/10.1016/s0016-5085(13)61154-3
https://doi.org/10.1016/s0016-5085(13)61154-3