Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Kir2"'
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Cerebral arteries contain two primary and interacting cell types, smooth muscle (SMCs) and endothelial cells (ECs), which are each capable of sensing particular hemodynamic forces to set basal tone and brain perfusion. These biomechanical stimuli hel
Externí odkaz:
https://doaj.org/article/77917d02c30948d3853486b78204a2db
Autor:
Jill R. Crittenden, Shenyu Zhai, Magdalena Sauvage, Takashi Kitsukawa, Eric Burguière, Morgane Thomsen, Hui Zhang, Cinzia Costa, Giuseppina Martella, Veronica Ghiglieri, Barbara Picconi, Karen A. Pescatore, Ellen M. Unterwald, Walker S. Jackson, David E. Housman, S. Barak Caine, David Sulzer, Paolo Calabresi, Anne C. Smith, D. James Surmeier, Ann M. Graybiel
Publikováno v:
Neurobiology of Disease, Vol 158, Iss , Pp 105473- (2021)
CalDAG-GEFI (CDGI) is a protein highly enriched in the striatum, particularly in the principal spiny projection neurons (SPNs). CDGI is strongly down-regulated in two hyperkinetic conditions related to striatal dysfunction: Huntington's disease and l
Externí odkaz:
https://doaj.org/article/dcb665d27eb248cbbbad7e35d7e418a7
Akademický článek
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Electrophysiological properties and molecular background of the zebrafish (Danio rerio) cardiac inward rectifier current (IK1) were examined. Ventricular myocytes of zebrafish have a robust (−6.7±1.2 pA pF−1 at −120 mV) strongly recti
Electrophysiological properties and molecular background of the zebrafish (Danio rerio) cardiac inward rectifier current (IK1) were examined. Ventricular myocytes of zebrafish have a robust (−6.7±1.2 pA pF−1 at −120 mV) strongly recti
Externí odkaz:
http://hdl.handle.net/10454/16502
Autor:
Lee L. Eckhardt, Louise Reilly
Publikováno v:
Heart rhythm
Potassium inward rectifier channel Kir2 is an important component of terminal cardiac repolarization and resting membrane stability. This functionality is part of balanced cardiac excitability and is a defining feature of excitable cardiac membranes.
Autor:
Yanjun Cui, Heike Wulff, Hai M. Nguyen, Yi-Je Chen, Jacopo Di Lucente, Lee-Way Jin, Izumi Maezawa, Michael W. Pennington, Rania H. Ibrahim
Publikováno v:
Glia, vol 68, iss 11
Glia
Glia
Microglia‐mediated inflammation exerts adverse effects in ischemic stroke and in neurodegenerative disorders such as Alzheimer's disease (AD). Expression of the voltage‐gated potassium channel Kv1.3 is required for microglia activation. Both gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0069fa37760a46b0ec9e0990954908a2
https://escholarship.org/uc/item/9nq1d3q2
https://escholarship.org/uc/item/9nq1d3q2
Autor:
Laura, van der Schoor, Emma J, van Hattum, Sophie M, de Wilde, Netanja I, Harlianto, Aart-Jan, van Weert, Meye, Bloothooft, Marcel A G, van der Heyden
Publikováno v:
International Journal of Molecular Sciences
Inward rectifier potassium ion channels (IK1-channels) of the Kir2.x family are responsible for maintaining a stable negative resting membrane potential in excitable cells, but also play a role in processes of non-excitable tissues, such as bone deve
Publikováno v:
Cellular and Molecular Biology. 64:47-54
Clinical and experimental studies show that epilepsy affects cardiac function; however, the underlying molecular mechanism has not been fully elucidated. Inwardly-rectifying potassium (Kir) channels transport K+ ions into excitable cells such as neur
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