Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Kipros Gabriel"'
Outer membrane vesicles from Neisseria gonorrhoeae target PorB to mitochondria and induce apoptosis.
Autor:
Pankaj Deo, Seong H Chow, Iain D Hay, Oded Kleifeld, Adam Costin, Kirstin D Elgass, Jhih-Hang Jiang, Georg Ramm, Kipros Gabriel, Gordon Dougan, Trevor Lithgow, Eva Heinz, Thomas Naderer
Publikováno v:
PLoS Pathogens, Vol 14, Iss 3, p e1006945 (2018)
Neisseria gonorrhoeae causes the sexually transmitted disease gonorrhoea by evading innate immunity. Colonizing the mucosa of the reproductive tract depends on the bacterial outer membrane porin, PorB, which is essential for ion and nutrient uptake.
Externí odkaz:
https://doaj.org/article/19a370dd541c457a8aeece8ff5d25289
Autor:
Pavel Dolezal, Margareta Aili, Janette Tong, Jhih-Hang Jiang, Carlo M T Marobbio, Sau Fung Lee, Ralf Schuelein, Simon Belluzzo, Eva Binova, Aurelie Mousnier, Gad Frankel, Giulia Giannuzzi, Ferdinando Palmieri, Kipros Gabriel, Thomas Naderer, Elizabeth L Hartland, Trevor Lithgow
Publikováno v:
PLoS Pathogens, Vol 8, Iss 1, p e1002459 (2012)
The Mitochondrial Carrier Family (MCF) is a signature group of integral membrane proteins that transport metabolites across the mitochondrial inner membrane in eukaryotes. MCF proteins are characterized by six transmembrane segments that assemble to
Externí odkaz:
https://doaj.org/article/0f5d265e5d654a888748be2592c79cc4
Autor:
Pavel Dolezal, Margareta Aili, Janette Tong, Jhih-Hang Jiang, Carlo M. T. Marobbio, Sau fung Lee, Ralf Schuelein, Simon Belluzzo, Eva Binova, Aurelie Mousnier, Gad Frankel, Giulia Giannuzzi, Ferdinando Palmieri, Kipros Gabriel, Thomas Naderer, Elizabeth L. Hartland, Trevor Lithgow
Publikováno v:
PLoS Pathogens, Vol 8, Iss 1 (2012)
Externí odkaz:
https://doaj.org/article/e0f508f5424540a6bdf51e8a6cccb35c
Autor:
Khatira Anwari, Sebastian Poggio, Andrew Perry, Xenia Gatsos, Sri Harsha Ramarathinam, Nicholas A Williamson, Nicholas Noinaj, Susan Buchanan, Kipros Gabriel, Anthony W Purcell, Christine Jacobs-Wagner, Trevor Lithgow
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8619 (2010)
Mitochondria are organelles derived from an intracellular alpha-proteobacterium. The biogenesis of mitochondria relies on the assembly of beta-barrel proteins into the mitochondrial outer membrane, a process inherited from the bacterial ancestor. Cau
Externí odkaz:
https://doaj.org/article/1ab660726c20443fac0654dc099b56fa
Autor:
Samuel L Palframan, Md. Toslim Mahmud, Kher Shing Tan, Rhys Grinter, Vicky Xin, Rhys A Dunstan, Diana Micati, Genevieve Kerr, Paul J McMurrick, Andrew Smith, Helen Abud, Thanh Ngoc Nguyen, Michael Lazarou, Oded Kleifeld, Trevor Lithgow, Timothy L Cover, Kipros Gabriel, Rebecca J Gorrell, Terry Kwok
Helicobacter pylori infection is the main cause of gastric cancer. Vacuolating cytotoxin A (VacA) is a H. pylori pore-forming toxin and a key determinant of gastric cancer risk. VacA is secreted as an 88-kDa polypeptide (p88) that upon interaction wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3531f1d9a0601f5f909a47e69c6580b1
https://doi.org/10.1101/2022.08.22.504206
https://doi.org/10.1101/2022.08.22.504206
Autor:
Kirstin Elgass, Iain D. Hay, Jhih-Hang Jiang, P. Deo, Seong Hoong Chow, Gordon Dougan, Oded Kleifeld, Kipros Gabriel, Georg Ramm, Eva Heinz, Thomas Naderer, Adam Costin, Trevor Lithgow
Publikováno v:
PLoS Pathogens, Vol 14, Iss 3, p e1006945 (2018)
PLoS Pathogens
PLoS Pathogens
Neisseria gonorrhoeae causes the sexually transmitted disease gonorrhoea by evading innate immunity. Colonizing the mucosa of the reproductive tract depends on the bacterial outer membrane porin, PorB, which is essential for ion and nutrient uptake.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a7dd9791cc50cfabcf59c462ff32e99
http://ora.ox.ac.uk/objects/uuid:
http://ora.ox.ac.uk/objects/uuid:
Publikováno v:
International Journal of Molecular Sciences, Vol 13, Iss 7, Pp 8038-8050 (2012)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
β-barrel proteins are the highly abundant in the outer membranes of Gram-negative bacteria and the mitochondria in eukaryotes. The assembly of β-barrels is mediated by two evolutionary conserved machineries; the β-barrel Assembly Machinery (BAM) i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6221011df91d65405ac6f17e027be34
http://www.mdpi.com/1422-0067/13/7/8038
http://www.mdpi.com/1422-0067/13/7/8038
Publikováno v:
IUBMB Life. 64:397-401
Bacterial infection has enormous global social and economic impacts stemming from effects on human health and agriculture. Although there are still many unanswered questions, decades of research has uncovered many of the pathogenic mechanisms at play
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72430846c4e2d21e58b9264f4194c7e8
https://doi.org/10.1002/iub.1021
https://doi.org/10.1002/iub.1021
Publikováno v:
Molecular Microbiology. 82:976-987
Mitochondria originated from Gram-negative bacteria through endosymbiosis. In modern day mitochondria, the Sorting and Assembly Machinery (SAM) is responsible for eukaryotic β-barrel protein assembly in the mitochondrial outer membrane. The SAM is t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a98f7facd43b9f57b46a6547a6c9e044
https://doi.org/10.1111/j.1365-2958.2011.07880.x
https://doi.org/10.1111/j.1365-2958.2011.07880.x
Autor:
Judith M. Müller, Michael J. Baker, Agnieszka Chacinska, Kipros Gabriel, Michael T. Ryan, Diana Stojanovski, Bernard Guiard, Nikolaus Pfanner, Agnes Schulze-Specking, Dusanka Milenkovic
Publikováno v:
ResearcherID
The Journal of Cell Biology
The Journal of Cell Biology
The biogenesis of mitochondrial intermembrane space proteins depends on specific machinery that transfers disulfide bonds to precursor proteins. The machinery shares features with protein relays for disulfide bond formation in the bacterial periplasm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6feb088987309158ba12af69dfffe77
https://doi.org/10.1083/jcb.200804095
https://doi.org/10.1083/jcb.200804095