Zobrazeno 1 - 10
of 616
pro vyhledávání: '"Kipp W"'
Autor:
Ramya Vunikili, Benjamin S. Glicksberg, Kipp W. Johnson, Joel T. Dudley, Lakshminarayanan Subramanian, Khader Shameer
Publikováno v:
Frontiers in Artificial Intelligence, Vol 4 (2021)
Objective: Opioids are a class of drugs that are known for their use as pain relievers. They bind to opioid receptors on nerve cells in the brain and the nervous system to mitigate pain. Addiction is one of the chronic and primary adverse events of p
Externí odkaz:
https://doaj.org/article/0b37d3999085491b956622172497bf3b
Autor:
Benjamin S. Glicksberg, Letizia Amadori, Nicholas K. Akers, Katyayani Sukhavasi, Oscar Franzén, Li Li, Gillian M. Belbin, Kristin L. Akers, Khader Shameer, Marcus A. Badgeley, Kipp W. Johnson, Ben Readhead, Bruce J. Darrow, Eimear E. Kenny, Christer Betsholtz, Raili Ermel, Josefin Skogsberg, Arno Ruusalepp, Eric E. Schadt, Joel T. Dudley, Hongxia Ren, Jason C. Kovacic, Chiara Giannarelli, Shuyu D. Li, Johan L. M. Björkegren, Rong Chen
Publikováno v:
BMC Medical Genomics, Vol 12, Iss S6, Pp 1-16 (2019)
Abstract Background Genetic loss-of-function variants (LoFs) associated with disease traits are increasingly recognized as critical evidence for the selection of therapeutic targets. We integrated the analysis of genetic and clinical data from 10,511
Externí odkaz:
https://doaj.org/article/a76b99477ddb49caaac1147906552dfc
Autor:
Kipp W. Johnson, Benjamin S. Glicksberg, Khader Shameer, Yuliya Vengrenyuk, Chayakrit Krittanawong, Adam J. Russak, Samin K. Sharma, Jagat N. Narula, Joel T. Dudley, Annapoorna S. Kini
Publikováno v:
EBioMedicine, Vol 44, Iss , Pp 41-49 (2019)
Background: Fibrous cap thickness (FCT), best measured by intravascular optical coherence tomography (OCT), is the most important determinant of plaque rupture in the coronary arteries. Statin treatment increases FCT and thus reduces the likelihood o
Externí odkaz:
https://doaj.org/article/5b8d5be20be9481d858631e574795afb
Autor:
Ishan Paranjpe, Kumardeep Chaudhary, Kipp W Johnson, Suraj K Jaladanki, Shan Zhao, Jessica K De Freitas, Elisabet Pujdas, Fayzan Chaudhry, Erwin P Bottinger, Matthew A Levin, Zahi A Fayad, Alexander W Charney, Jane Houldsworth, Carlos Cordon-Cardo, Benjamin S Glicksberg, Girish N Nadkarni
Publikováno v:
PLoS ONE, Vol 16, Iss 2, p e0247366 (2021)
BackgroundSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the associated Coronavirus Disease 2019 (COVID-19) is a public health emergency. Acute kidney injury (AKI) is a common complication in hospitalized patients with COVID-19 alth
Externí odkaz:
https://doaj.org/article/268020d196c74ed3a3d845b1844c5d0c
Autor:
Girish N Nadkarni, Zahi A Fayad, Benjamin S Glicksberg, David L Reich, Prem Timsina, Arash Kia, Patricia Kovatch, Jessica K De Freitas, Paul O’Reilly, Allan Just, Dennis Charney, Ishan Paranjpe, Ross O'Hagan, Adam J Russak, Anuradha Lala, Riccardo Miotto, Akhil Vaid, Kipp W Johnson, Matteo Danieletto, Eddye Golden, Dara Meyer, Manbir Singh, Sulaiman Somani, Arjun Kapoor, Sayan Manna, Udit Nangia, Suraj K Jaladanki, Laura M Huckins, Patricia Glowe, Robert M Freeman, Matthew A Levin, Jeffrey Jhang, Adolfo Firpo, Joseph Finkelstein, Judith A Aberg, Emilia Bagiella, Carol R Horowitz, Barbara Murphy, Jagat Narula, Eric J Nestler, V Fuster, Carlos Cordon-Cardo, Erwin P Bottinger, Alexander W Charney
Publikováno v:
BMJ Open, Vol 10, Iss 11 (2020)
Objective The COVID-19 pandemic is a global public health crisis, with over 33 million cases and 999 000 deaths worldwide. Data are needed regarding the clinical course of hospitalised patients, particularly in the USA. We aimed to compare clinical c
Externí odkaz:
https://doaj.org/article/49d3bda439074873861d39f10d7bca65
Autor:
Farhan Chaudhry, Rachel J. Hunt, Prashant Hariharan, Sharath Kumar Anand, Surya Sanjay, Ellen E. Kjoller, Connor M. Bartlett, Kipp W. Johnson, Phillip D. Levy, Houtan Noushmehr, Ian Y. Lee
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
The neurological ICU (neuro ICU) often suffers from significant limitations due to scarce resource availability for their neurocritical care patients. Neuro ICU patients require frequent neurological evaluations, continuous monitoring of various phys
Externí odkaz:
https://doaj.org/article/63b5b8ddcbc14d7c9b965a11abc7b311
Autor:
Chayakrit Krittanawong, Kipp W. Johnson, Edward Choi, Scott Kaplin, Eric Venner, Mullai Murugan, Zhen Wang, Benjamin S. Glicksberg, Christopher I. Amos, Michael C. Schatz, W. H. Wilson Tang
Publikováno v:
Life, Vol 12, Iss 2, p 279 (2022)
Polygenic diseases, which are genetic disorders caused by the combined action of multiple genes, pose unique and significant challenges for the diagnosis and management of affected patients. A major goal of cardiovascular medicine has been to underst
Externí odkaz:
https://doaj.org/article/3da1fb785d864729956a2c0c26617b1c
Autor:
Khader Shameer, M. Mercedes Perez-Rodriguez, Roy Bachar, Li Li, Amy Johnson, Kipp W. Johnson, Benjamin S. Glicksberg, Milo R. Smith, Ben Readhead, Joseph Scarpa, Jebakumar Jebakaran, Patricia Kovatch, Sabina Lim, Wayne Goodman, David L. Reich, Andrew Kasarskis, Nicholas P. Tatonetti, Joel T. Dudley
Publikováno v:
BMC Medical Informatics and Decision Making, Vol 18, Iss S3, Pp 1-11 (2018)
Abstract Background Worldwide, over 14% of individuals hospitalized for psychiatric reasons have readmissions to hospitals within 30 days after discharge. Predicting patients at risk and leveraging accelerated interventions can reduce the rates of ea
Externí odkaz:
https://doaj.org/article/607b367228c842dc9e85593c26b8353a
Autor:
Surbhi Chamaria, Kipp W. Johnson, Yuliya Vengrenyuk, Usman Baber, Khader Shameer, Aparna A. Divaraniya, Benjamin S. Glicksberg, Li Li, Samit Bhatheja, Pedro Moreno, Akiko Maehara, Roxana Mehran, Joel T. Dudley, Jagat Narula, Samin K. Sharma, Annapoorna S. Kini
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Residual atherothrombotic risk remains higher in patients with versus without diabetes mellitus (DM) despite statin therapy. The underlying mechanisms are unclear. This is a retrospective post-hoc analysis of the YELLOW II trial, comparing p
Externí odkaz:
https://doaj.org/article/02e1b65f7bc7426a94ade020e84c3688
Autor:
Kipp W. Johnson, BS, Khader Shameer, PhD, Benjamin S. Glicksberg, BS, Ben Readhead, MBBS, Partho P. Sengupta, MD, Johan L.M. Björkegren, MD, PhD, Jason C. Kovacic, MD, PhD, Joel T. Dudley, PhD
Publikováno v:
JACC: Basic to Translational Science, Vol 2, Iss 3, Pp 311-327 (2017)
Summary: The traditional paradigm of cardiovascular disease research derives insight from large-scale, broadly inclusive clinical studies of well-characterized pathologies. These insights are then put into practice according to standardized clinical
Externí odkaz:
https://doaj.org/article/160fa34e57b44f23aa4c2fb4cae8ba0e