Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Kip A West"'
Autor:
Brenda C O'Connell, Katie O'Callaghan, Bonnie Tillotson, Mark Douglas, Nafeeza Hafeez, Kip A West, Howard Stern, Janid A Ali, Paul Changelian, Christian C Fritz, Vito J Palombella, Karen McGovern, Jeffery L Kutok
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e115228 (2014)
HSP90 inhibitors are currently undergoing clinical evaluation in combination with antimitotic drugs in non-small cell lung cancer (NSCLC), but little is known about the cellular effects of this novel drug combination. Therefore, we investigated the m
Externí odkaz:
https://doaj.org/article/9d093119cf444dc3945b927b8fef1652
Autor:
Daniel S. Leventhal, Anna Sokolovska, Ning Li, Christopher Plescia, Starsha A. Kolodziej, Carey W. Gallant, Rudy Christmas, Jian-Rong Gao, Michael J. James, Andres Abin-Fuentes, Munira Momin, Christopher Bergeron, Adam Fisher, Paul F. Miller, Kip A. West, Jose M. Lora
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Synthetic biology can be used to create rationally designed living therapeutics. Here the authors engineer E. coli Nissle to target STING activation in antigen presenting cells for the treatment of solid tumors and demonstrate preclinical activity in
Externí odkaz:
https://doaj.org/article/c274837c940442a5b5b9051d086275aa
Autor:
José Baselga, Claudia Aura, José Jimenez, Ludmila Prudkin, Varenka Rodriguez, Kip A. West, Kelly L. Slocum, Alice R. Lim, Olga Rodriguez, Marta Guzman, Emmanuel Normant, Violeta Serra, Maurizio Scaltriti
Supplementary Figure 3 from Antitumor Activity of the Hsp90 Inhibitor IPI-504 in HER2-Positive Trastuzumab-Resistant Breast Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86f6adafe9a431b9bcbd2909aa5581fe
https://doi.org/10.1158/1535-7163.22497190
https://doi.org/10.1158/1535-7163.22497190
Autor:
José Baselga, Claudia Aura, José Jimenez, Ludmila Prudkin, Varenka Rodriguez, Kip A. West, Kelly L. Slocum, Alice R. Lim, Olga Rodriguez, Marta Guzman, Emmanuel Normant, Violeta Serra, Maurizio Scaltriti
Supplementary Figure 1 from Antitumor Activity of the Hsp90 Inhibitor IPI-504 in HER2-Positive Trastuzumab-Resistant Breast Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bad67847ef5041dbe893b8aa7bc98cb
https://doi.org/10.1158/1535-7163.22497196
https://doi.org/10.1158/1535-7163.22497196
Autor:
José Baselga, Claudia Aura, José Jimenez, Ludmila Prudkin, Varenka Rodriguez, Kip A. West, Kelly L. Slocum, Alice R. Lim, Olga Rodriguez, Marta Guzman, Emmanuel Normant, Violeta Serra, Maurizio Scaltriti
Supplementary Figure 2 from Antitumor Activity of the Hsp90 Inhibitor IPI-504 in HER2-Positive Trastuzumab-Resistant Breast Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57460a9bcd3d82a689dda3fd312a969e
https://doi.org/10.1158/1535-7163.22497193
https://doi.org/10.1158/1535-7163.22497193
Autor:
José Baselga, Claudia Aura, José Jimenez, Ludmila Prudkin, Varenka Rodriguez, Kip A. West, Kelly L. Slocum, Alice R. Lim, Olga Rodriguez, Marta Guzman, Emmanuel Normant, Violeta Serra, Maurizio Scaltriti
Supplementary Figure Legends 1-3 from Antitumor Activity of the Hsp90 Inhibitor IPI-504 in HER2-Positive Trastuzumab-Resistant Breast Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e8af4d7bd1c867b5a33e4eca1792778
https://doi.org/10.1158/1535-7163.22497187.v1
https://doi.org/10.1158/1535-7163.22497187.v1
Autor:
Roger Geiger, Jose M. Lora, Jean-Philippe Theurillat, Michael J. James, Fernando P. Canale, Wenjie Jin, Camilla Basso, Ning Li, Anna Sokolovska, Daniel S. Leventhal, Kip A. West, Michela Perotti, Federica Sallusto
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background The availability of L-arginine in tumors is a key determinant of an efficient anti-tumor T cell response. Consequently, the elevation of typically low L-arginine levels within the tumor may greatly potentiate the anti-tumor responses of im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db45532a9e18a9d09c577f58ad94f6f6
https://doaj.org/article/a0be3067cdbb4c43b08fc905e02ccd77
https://doaj.org/article/a0be3067cdbb4c43b08fc905e02ccd77
Autor:
Carey W. Gallant, Christopher Plescia, Paul F. Miller, Michael J. James, Kip A. West, Rudy Christmas, Daniel S. Leventhal, Jian-Rong Gao, Ning Li, Adam B. Fisher, Starsha Kolodziej, Munira Momin, Christopher Bergeron, Anna Sokolovska, Andres Abin-Fuentes, Jose M. Lora
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Synthetic biology is a powerful tool to create therapeutics which can be rationally designed to enable unique and combinatorial functionalities. Here we utilize non-pathogenic E coli Nissle as a versatile platform for the development of a living biot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76faebc0aaf2c966e92df019edccdf75
http://europepmc.org/articles/PMC7264239
http://europepmc.org/articles/PMC7264239
Autor:
Paul F. Miller, Mary Castillo, Caroline B. Kurtz, Kip A. West, Philippa J. Reeder, Binh Ha, Adam B. Fisher, Yves Millet, Vincent M. Isabella, Cami Leigh Anderson, David Lubkowicz, Dean Falb, Sarah Rowe, Christopher Bergeron, Sarah E. Guilmain, Ning Li, Munira Momin
Publikováno v:
Nature Biotechnology. 36:857-864
Phenylketonuria (PKU) is a genetic disease that is characterized by an inability to metabolize phenylalanine (Phe), which can result in neurotoxicity. To provide a potential alternative to a protein-restricted diet, we engineered Escherichia coli Nis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ece3dcd9adaff9fea0acbd8dfe363f76
https://doi.org/10.1038/nbt.4222
https://doi.org/10.1038/nbt.4222
Autor:
Fernando P, Canale, Camilla, Basso, Gaia, Antonini, Michela, Perotti, Ning, Li, Anna, Sokolovska, Julia, Neumann, Michael J, James, Stefania, Geiger, Wenjie, Jin, Jean-Philippe, Theurillat, Kip A, West, Daniel S, Leventhal, Jose M, Lora, Federica, Sallusto, Roger, Geiger
Publikováno v:
Nature. 598(7882)
The availability of L-arginine in tumours is a key determinant of an efficient anti-tumour T cell response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::39eb581e48858585058b5fa120e1745e
https://pubmed.ncbi.nlm.nih.gov/34906317
https://pubmed.ncbi.nlm.nih.gov/34906317