Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Kinuyo Ozaki"'
Autor:
Masayoshi Otake, Michihiro Imamura, Satoko Enya, Akihisa Kangawa, Masatoshi Shibata, Kinuyo Ozaki, Koichi Kimura, Etsuro Ono, Yoshitsugu Aoki
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-11 (2024)
Abstract Duchenne muscular dystrophy (DMD) is an intractable X-linked muscular dystrophy caused by mutations in the DMD gene. While many animal models have been used to study the disease, translating findings to humans has been challenging. Micromini
Externí odkaz:
https://doaj.org/article/175119c4150e40bea513c5ea0a05a16b
Autor:
Yukiko Tomioka, Yoshikazu Fujimoto, Kanji Nakai, Kinuyo Ozaki, Sayo Yamamoto, Haruka Suyama, Masami Morimatsu, Toshihiro Ito, Etsuro Ono
Publikováno v:
Biochemistry and Biophysics Reports, Vol 5, Iss C, Pp 196-202 (2016)
Transgenic mouse lines expressing a soluble form of human nectin-2 (hNectin-2Ig Tg) exhibited distinctive elevation of amylase and lipase levels in the sera. In this study, we aimed to clarify the histopathology and to propose the transgenic mouse li
Externí odkaz:
https://doaj.org/article/ae22647a17444e3ebeec4747a6530b81
Autor:
Juan C López-Ramos, Yukiko Tomioka, Masami Morimatsu, Sayo Yamamoto, Kinuyo Ozaki, Etsuro Ono, José M Delgado-García
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12123 (2010)
The cerebellum in transgenic mice expressing pseudorabies virus immediate-early protein IE180 (TgIE96) was substantially diminished in size, and its histoarchitecture was severely disorganized, resulting in severe ataxia. TgIE96 mice can therefore be
Externí odkaz:
https://doaj.org/article/b8e664ab071a453fb4c132a0389c8e04
Autor:
Etsuro Ono, Keiko Takeda, Yoshikazu Fujimoto, Shin Ichi Hikita, Koh Hei Sonoda, Hiroki Takakuwa, Kinuyo Ozaki, Hideya Inoue
Publikováno v:
Journal of Medical Virology. 91:820-828
Ocular herpes, caused by herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) infections, remains an important corneal disease, which may result in loss of vision. Because the frequency of acyclovir resistance in HSV has increased, novel antiviral
Autor:
Yoshikazu Fujimoto, Yukiko Tomioka, Haruka Suyama, Sayo Yamamoto, Masami Morimatsu, Toshimitsu Uede, Hiroki Takakuwa, Kinuyo Ozaki, Keiko Takeda, Etsuro Ono
Publikováno v:
Journal of General Virology. 98:1815-1822
Herpesvirus entry mediator A (HVEM), nectin-1 and nectin-2 are cellular receptors of glycoprotein D (gD) of herpes simplex virus type-2 (HSV-2). It has been shown that soluble forms of HSV gD receptors have the antiviral potential in cultured cells a
Autor:
Etsuro Ono, Sayo Yamamoto, Keiko Takeda, Kenji Kyogoku, Yoshikazu Fujimoto, Kinuyo Ozaki, Haruka Suyama
Publikováno v:
The Journal of Veterinary Medical Science
RNA interference (RNAi) can inhibit Influenza A virus (IAV) infection in a gene-specific manner. In this study, we constructed a transgene expressing a short hairpin RNA (shRNA) that targets the noncoding region of the IAV RNA gene encoding nucleopro
Autor:
Masami Morimatsu, Mitsumasa Saito, Yukiko Tomioka, Etsuro Ono, Haruka Suyama, Sayo Yamamoto, Kinuyo Ozaki, Shin-ichi Yoshida, Ken-ichi Nishijima
Publikováno v:
Microbial Pathogenesis. 99:106-110
Group B Streptococcus (GBS) is a leading cause of invasive bacterial infections in human newborns. A key GBS virulence factor is its capsular polysaccharide (CPS), possessing terminal sialic acid residues that suppress host immune response and provid
Autor:
Hiroki Takakuwa, Hiroshi Kida, Kinuyo Ozaki, Masahiro Maeda, Ken-ichi Nishijima, Yoshikazu Fujimoto, Etsuro Ono, Koichi Otsuki
Publikováno v:
The Veterinary Journal. 198:487-493
The polymerase basic 2 (PB2) protein is one of four proteins that make up the influenza A virus replication complex, which is responsible for viral gene transcription and replication. To assess the antiviral potential of an anti-PB2 monoclonal antibo
Autor:
Le Quynh Mai, Kinuyo Ozaki, Etsuro Ono, Toshiyo Yabuta, Hiroki Takakuwa, Gen Ichiro Uechi, Toshihiro Ito, Yoshikazu Fujimoto, Masami Morimatsu, Haruka Suyama, Yukiko Tomioka, Koichi Otsuki, Tetsu Yamashiro, Sayo Yamamoto
Publikováno v:
The Journal of general virology. 97(9)
The nucleoprotein (NP) possesses regions that are highly conserved among influenza A viruses, and has therefore been one of the target viral proteins for development of a universal influenza vaccine. It has been expected that human or humanized antib
Publikováno v:
Acta virologica. 60(1)
Cell entry of herpes simplex virus type 2 (HSV-2) requires the interaction of viral glycoprotein D (gD) with the receptor nectin-1 and herpesvirus entry mediator (HVEM). In addition, it is known that nectin-2 is also functional as a receptor for HSV-