Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Kinue Ohguro"'
Autor:
Daisuke Oka, Naomitsu Yamaya, Takuya Kuno, Yuta Asakawa, Toshiyuki Shiragiku, Liang Chen, Jingbo Xue, Abudusaimi Mamuti, Fangguo Ye, Jiangqin Sun, Kinue Ohguro, Hisashi Miyamoto, Yukitaka Uematsu, Katsuya Inagaki, Jie-Fei Cheng, Makoto Matsumoto
Publikováno v:
Antimicrob Agents Chemother
Autor:
Katsuya Inagaki, Daisuke Oka, Hisashi Miyamoto, Jingbo Xue, Ye Fangguo, Yuta Asakawa, Liang Chen, Yukitaka Uematsu, Naomitsu Yamaya, Abudusaimi Mamuti, Takuya Kuno, Jiangqin Sun, Jie-Fei Cheng, Toshiyuki Shiragiku, Kinue Ohguro, Makoto Matsumoto
Publikováno v:
Antimicrobial Agents and Chemotherapy
OPS-2071 is a novel quinolone antibacterial agent characterized by low oral absorption that reduces the risk of adverse events typical of fluoroquinolone class antibiotics. The in vitro and in vivo antibacterial activities of OPS-2071 against Clostri
Autor:
Yongge Liu, Rajesh Gupta, Hidekaza Ishida, Masuhiro Yoshitake, Lawrence Geiter, Jeffrey Hafkin, Kinue Ohguro, Makoto Matsumoto
Publikováno v:
Tuberculosis. 111:20-30
Tuberculosis (TB), caused by Mycobacterium tuberculosis (MTB), is the leading cause of death from an infectious disease globally. The widespread and ever-increasing resistance to TB drugs is reducing the effectiveness of treatment and jeopardizing TB
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 7:1721-1724
For the purpose of developing new antiseptics, we searched for compounds having high biocidal activity covering both gram-positive and gram-negative bacteria. Accordingly, we designed 1,5-disubstituted biguanides and synthesized them using two altern
Autor:
Seiji Morita, Kinue Ohguro, Kenji Otsubo, Kazunori Ohmori, Minoru Uchida, Tadaaki Ohtani, Jun Matsubara, Yoshikazu Kawano
Publikováno v:
Chemical and Pharmaceutical Bulletin. 43:2246-2252
Grepafloxacin (1-cyclopropyl-1,4-dihydro-6-fluoro-5-methyl-7-(3-methyl-1-piperazinyl )-4-oxo-3-quinoline-carboxylic acid, OPC-17116) (1) exhibits potent and broad-spectrum in vitro and in vivo antibacterial activity. In order to identify the structur
Autor:
H Yoneda, T Imada, Hisashi Tamaoka, Kinue Ohguro, H Wakebe, F Mukai, Kazunori Ohmori, Y Yabuuchi
Publikováno v:
Antimicrobial Agents and Chemotherapy. 38:2340-2345
The antibacterial activity of OPC-17116, a new fluoroquinolone antibacterial agent, against important pathogens that cause respiratory tract infections was evaluated in vitro and in vivo and compared with those of ciprofloxacin, ofloxacin, and norflo