Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Kinue Nishioka"'
Autor:
Tomomi Makimura, Kinue Nishioka, Takahiro Nonaka, Yoshiaki Uyama, Akihiro Ishiguro, Mitsune Yamaguchi
Publikováno v:
Clinical pharmacology and therapeutics. 111(1)
There is growing interest in the utilization of real-world data (RWD) and real-world evidence (RWE) for regulatory purposes. However, there are challenges in the practical utilization of RWD to provide RWE as a basis for regulatory decision making. T
Autor:
Kinue Nishioka
Publikováno v:
Folia Pharmacologica Japonica. 141:155-159
Autor:
Hitoshi Kurose, Takahiro Iwamoto, Mayumi Hirano, Ryuji Inoue, Michio Nakaya, Zhong Jian, Shota Saiki, Motohiro Nishida, Yoji Sato, Satomi Kita, Marina Ariyoshi, Kinue Nishioka, Katsuya Hirano
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 31:2278-2286
Objective— The goal of this study was to determine whether inhibition of transient receptor potential canonical (TRPC) channels underlies attenuation of angiotensin II (Ang II)–induced vasoconstriction by phosphodiesterase (PDE) 3 inhibition. Met
Publikováno v:
Biochemical Pharmacology. 58:1349-1359
Omeprazole and pantoprazole are known to be irreversible, SH-acting inhibitors of gastric H+,K+-adenosine triphosphatase (H+,K+-ATPase). Both drugs concentration-dependently and pH-dependently inhibited K+-dependent p-nitrophenyl phosphatase (K+-pNPP
Autor:
Kuniko Matsumura-Takeda, Kinue Nishioka, Takuma Kawakami, Yoshimasa Isakari, Takao Taki, Yasuo Harada, Toshihide Ono, Shinji Sogo
Publikováno v:
Stem cells (Dayton, Ohio). 25(4)
Murine megakaryocytes (MKs) are defined by CD41/CD61 expression and acetylcholinesterase (AChE) activity; however, their stages of differentiation in bone marrow (BM) have not been fully elucidated. In murine lineage-negative (Lin−)/CD45+ BM cells,
Autor:
Kuniko Matsumura-Takeda, Shinji Sogo, Yasuo Harada, Yoshimasa Isakari, Kinue Nishioka, Takao Taki, Takuma Kawakami, Toshihide Ono
Publikováno v:
Blood. 106:2265-2265
Platelets (PLT) are produced from megakaryocytes (Mks) via proplatelet formation (PPF). However, the molecular mechanisms from Mks to PPF are not clearly elucidated, because the maturational steps of the Mks in bone marrow (BM) are not analyzed in de