Targeting SUMOylation dependency in human cancer stem cells through a unique SAE2 motif revealed by chemical genomics.

Autor: Benoit YD; Stem Cell and Cancer Research Institute, McMaster University, Hamilton, ON L8S 4K1, Canada; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada., Mitchell RR; Stem Cell and Cancer Research Institute, McMaster University, Hamilton, ON L8S 4K1, Canada., Wang W; M.G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton L8S 4K1, Canada., Orlando L; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8S 4K1, Canada., Boyd AL; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8S 4K1, Canada., Tanasijevic B; Stem Cell and Cancer Research Institute, McMaster University, Hamilton, ON L8S 4K1, Canada., Aslostovar L; Stem Cell and Cancer Research Institute, McMaster University, Hamilton, ON L8S 4K1, Canada., Shapovalova Z; Stem Cell and Cancer Research Institute, McMaster University, Hamilton, ON L8S 4K1, Canada., Doyle M; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8S 4K1, Canada., Bergin CJ; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada., Vojnits K; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8S 4K1, Canada., Casado FL; Stem Cell and Cancer Research Institute, McMaster University, Hamilton, ON L8S 4K1, Canada., Di Lu J; Stem Cell and Cancer Research Institute, McMaster University, Hamilton, ON L8S 4K1, Canada., Porras DP; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8S 4K1, Canada., García-Rodriguez JL; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8S 4K1, Canada., Russell J; Stem Cell and Cancer Research Institute, McMaster University, Hamilton, ON L8S 4K1, Canada., Zouggar A; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada., Masibag AN; Department of Cellular and Molecular Medicine, University of Ottawa, Ottawa, ON K1H 8M5, Canada., Caba C; M.G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton L8S 4K1, Canada; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8S 4K1, Canada., Koteva K; M.G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton L8S 4K1, Canada; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8S 4K1, Canada., Kinthada LK; M.G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton L8S 4K1, Canada; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8S 4K1, Canada., Patel JS; Department of Biological Sciences, Institute for Modeling Collaboration and Innovation, University of Idaho, Moscow, ID 83844, USA., Andres SN; M.G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton L8S 4K1, Canada; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8S 4K1, Canada., Magolan J; M.G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton L8S 4K1, Canada; Department of Chemistry and Chemical Biology, McMaster University, Hamilton, ON L8S 4K1, Canada; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8S 4K1, Canada., Collins TJ; Stem Cell and Cancer Research Institute, McMaster University, Hamilton, ON L8S 4K1, Canada., Wright GD; M.G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton L8S 4K1, Canada; Department of Chemistry and Chemical Biology, McMaster University, Hamilton, ON L8S 4K1, Canada; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8S 4K1, Canada. Electronic address: wrightge@mcmaster.ca., Bhatia M; Stem Cell and Cancer Research Institute, McMaster University, Hamilton, ON L8S 4K1, Canada; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8S 4K1, Canada. Electronic address: mbhatia@mcmaster.ca.

Publikováno v: Cell chemical biology [Cell Chem Biol] 2021 Oct 21; Vol. 28 (10), pp. 1394-1406.e10. Date of Electronic Publication: 2021 May 11.

Lewis Acid-Catalyzed Malonate Addition onto 3-Hydroxy-2-oxindoles: Mechanistic Consideration and Synthetic Approaches to the Pyrroloindoline Alkaloids.

Autor: Naresh Babu K; Department of Chemistry , Indian Institute of Science Education and Research Bhopal , Bhopal Bypass Road , Bhopal , Madhya Pradesh 462 066 , India., Kariyandi NR; Department of Chemistry , Indian Institute of Science Education and Research Bhopal , Bhopal Bypass Road , Bhopal , Madhya Pradesh 462 066 , India., Saheeda M K S; Department of Chemistry , Indian Institute of Science Education and Research Bhopal , Bhopal Bypass Road , Bhopal , Madhya Pradesh 462 066 , India., Kinthada LK; Department of Chemistry , Indian Institute of Science Education and Research Bhopal , Bhopal Bypass Road , Bhopal , Madhya Pradesh 462 066 , India., Bisai A; Department of Chemistry , Indian Institute of Science Education and Research Bhopal , Bhopal Bypass Road , Bhopal , Madhya Pradesh 462 066 , India.

Publikováno v: The Journal of organic chemistry [J Org Chem] 2018 Oct 19; Vol. 83 (20), pp. 12664-12682. Date of Electronic Publication: 2018 Oct 03.

FeCl 3 -Catalyzed Allylation Reactions onto 3-Hydroxy-2-oxindoles: Formal Total Syntheses of Bis-cyclotryptamine Alkaloids, (±)-Chimonanthine, and (±)-Folicanthine.

Autor: Kinthada LK; Department of Chemistry, Indian Institute of Science Education and Research Bhopal , Bhopal Bypass Road, Bhopal, Madhya Pradesh 462 066, India., Medisetty SR; Department of Chemistry, Indian Institute of Science Education and Research Bhopal , Bhopal Bypass Road, Bhopal, Madhya Pradesh 462 066, India., Parida A; Department of Chemistry, Indian Institute of Science Education and Research Bhopal , Bhopal Bypass Road, Bhopal, Madhya Pradesh 462 066, India., Babu KN; Department of Chemistry, Indian Institute of Science Education and Research Bhopal , Bhopal Bypass Road, Bhopal, Madhya Pradesh 462 066, India., Bisai A; Department of Chemistry, Indian Institute of Science Education and Research Bhopal , Bhopal Bypass Road, Bhopal, Madhya Pradesh 462 066, India.

Publikováno v: The Journal of organic chemistry [J Org Chem] 2017 Aug 18; Vol. 82 (16), pp. 8548-8567. Date of Electronic Publication: 2017 Aug 07.

Friedel-Crafts alkylations of electron-rich aromatics with 3-hydroxy-2-oxindoles: scope and limitations.

Autor: Kinthada LK; Department of Chemistry, Indian Institute of Science Education and Research Bhopal, Bhopal, M.P.-462 066, India. alakesh@iiserb.ac.in., Ghosh S, Babu KN, Sharique M, Biswas S, Bisai A

Publikováno v: Organic & biomolecular chemistry [Org Biomol Chem] 2014 Nov 07; Vol. 12 (41), pp. 8152-73. Date of Electronic Publication: 2014 Sep 02.

Lewis acid-catalyzed Friedel-Crafts alkylations of 3-hydroxy-2-oxindole: an efficient approach to the core structure of azonazine.

Autor: Ghosh S; Department of Chemistry, Indian Institute of Science Education and Research Bhopal, Bhopal, MP 460 023, India., Kinthada LK, Bhunia S, Bisai A

Publikováno v: Chemical communications (Cambridge, England) [Chem Commun (Camb)] 2012 Oct 18; Vol. 48 (81), pp. 10132-4.