Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Kinnosuke Yahiro"'
Autor:
Daiki Yamaguchi, Go Kamoshida, Syun Kawakubo, Saki Azuma, Takamitsu Tsuji, Nobuo Kitada, Ryohei Saito-Moriya, Noriteru Yamada, Rentaro Tanaka, Ayane Okuda, Keisuke Ueyama, Shingo Isaka, Manaha Tomita, Ryuichi Nakano, Yuji Morita, Hisakazu Yano, Shojiro A. Maki, Kinnosuke Yahiro, Shinichi Kato
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 11 (2024)
ABSTRACT In vivo imaging of bacterial infection models enables noninvasive and temporal analysis of individuals, enhancing our understanding of infectious disease pathogenesis. Conventional in vivo imaging methods for bacterial infection models invol
Externí odkaz:
https://doaj.org/article/da2b54a6352d43f0b03674716c983dad
Autor:
Kazuya Ozaki, Hiyo Nagahara, Asaka Kawamura, Takashi Ohgita, Sachika Higashi, Kohei Ogura, Hiroyasu Tsutsuki, Sunao Iyoda, Atsushi Yokotani, Toshiyuki Yamaji, Joel Moss, Kinnosuke Yahiro
Publikováno v:
Toxins, Vol 16, Iss 9, p 380 (2024)
Vibrio cholerae is an important foodborne pathogen. Cholix cytotoxin (Cholix), produced by V. cholerae, is a novel eukaryotic elongation factor 2 (eEF2) adenosine diphosphate ribosyltransferase that causes host cell death by inhibiting protein synthe
Externí odkaz:
https://doaj.org/article/0f97bb15ea894791aad9c623a0d9ca3c
Autor:
Tatsuya Kobayashi, Akira Mitsuhashi, Piao Hongying, Masashi Shioya, Katsushi Kojima, Kyoko Nishikimi, Kinnosuke Yahiro, Makio Shozu
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Bexarotene selectively activates retinoid X receptor, which is a commonly used anticancer agent for cutaneous T-cell lymphoma. In this study, we aimed to investigate the anticancer effect of bexarotene and its underlying mechanism in ovarian
Externí odkaz:
https://doaj.org/article/99119a21b154411cb393a094ba1fe253
Publikováno v:
STAR Protocols, Vol 3, Iss 4, Pp 101741- (2022)
Summary: Infection of mice with Citrobacter rodentium is a useful model for studying the pathogenicity of enteropathogenic and enterohemorrhagic Escherichia coli, pathogens that have a close association with humans. Here, we provide a protocol detail
Externí odkaz:
https://doaj.org/article/f36060513e2f48ac99f5b9268442e4f7
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-11 (2021)
Abstract Locus for Enterocyte Effacement (LEE)-positive Shiga-toxigenic Escherichia coli (STEC) contributes to many global foodborne diseases, with infection characterized by severe gastrointestinal symptoms, including bloody diarrhea. The incidence
Externí odkaz:
https://doaj.org/article/c2e2c7f6840245439c4e19b51fc61a57
Autor:
Go Kamoshida, Noriteru Yamada, Tomoka Nakamura, Daiki Yamaguchi, Daichi Kai, Maho Yamashita, Chiaki Hayashi, Nana Kanda, Moe Sakaguchi, Hitoshi Morimoto, Teppei Sawada, Tomoko Okada, Yuki Kaya, Norihiko Takemoto, Kinnosuke Yahiro
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 5 (2022)
ABSTRACT Colistin, which targets lipopolysaccharide (LPS), is used as a last-resort drug against severe infections caused by drug-resistant Acinetobacter baumannii. However, A. baumannii possesses two colistin-resistance mechanisms. LPS modification
Externí odkaz:
https://doaj.org/article/3bbb1f6d404b441da29831f1a009ecf4
Autor:
Hiroyasu Tsutsuki, Tianli Zhang, Kinnosuke Yahiro, Katsuhiko Ono, Yukio Fujiwara, Sunao Iyoda, Fan-Yan Wei, Kazuaki Monde, Kazuko Seto, Makoto Ohnishi, Hiroyuki Oshiumi, Takaaki Akaike, Tomohiro Sawa
Publikováno v:
iScience, Vol 25, Iss 4, Pp 104050- (2022)
Summary: Subtilase cytotoxin (SubAB) is an AB5 toxin mainly produced by the locus of enterocyte effacement-negative Shiga-toxigenic Escherichia coli (STEC) strain such as O113:H21, yet the contribution of SubAB to STEC infectious disease is unclear.
Externí odkaz:
https://doaj.org/article/5a42395178624e25b36725b46c736b1c
Autor:
Toshiyuki Yamaji, Hisatoshi Hanamatsu, Tsuyoshi Sekizuka, Makoto Kuroda, Norimasa Iwasaki, Makoto Ohnishi, Jun-ichi Furukawa, Kinnosuke Yahiro, Kentaro Hanada
Publikováno v:
iScience, Vol 15, Iss , Pp 407-420 (2019)
Summary: Subtilase cytotoxin (SubAB) is a virulence factor produced by locus of enterocyte effacement-negative Shiga-toxigenic Escherichia coli strains. The toxin recognizes sialoglycans for entry and cleaves an endoplasmic reticulum chaperon, bindin
Externí odkaz:
https://doaj.org/article/28d13907dec84b66b961d79fc3ec1972
Autor:
Ayaka Harada, Hiroyasu Tsutsuki, Tianli Zhang, Kinnosuke Yahiro, Tomohiro Sawa, Takuro Niidome
Publikováno v:
Nanomaterials, Vol 12, Iss 13, p 2161 (2022)
Advances in drug delivery systems (DDSs) have enabled the specific delivery of drugs to target cells. Subtilase cytotoxin (SubAB) produced by certain enterohemorrhagic Escherichia coli strains induces endoplasmic reticulum (ER) stress and suppresses
Externí odkaz:
https://doaj.org/article/15ba408034274fc29b5c8652a3aecdc9
Autor:
Masayuki Nakano, Kinnosuke Yahiro, Eiki Yamasaki, Hisao Kurazono, Junko Akada, Yoshio Yamaoka, Takuro Niidome, Masanori Hatakeyama, Hidekazu Suzuki, Taro Yamamoto, Joel Moss, Hajime Isomoto, Toshiya Hirayama
Publikováno v:
Disease Models & Mechanisms, Vol 9, Iss 12, Pp 1473-1481 (2016)
Helicobacter pylori, a major cause of gastroduodenal diseases, produces vacuolating cytotoxin (VacA) and cytotoxin-associated gene A (CagA), which seem to be involved in virulence. VacA exhibits pleiotropic actions in gastroduodenal disorders via its
Externí odkaz:
https://doaj.org/article/b3d29d1cb8424198a3833f2db56c8fab