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pro vyhledávání: '"Kinney, Justin B."'
The formation, dissolution, and dynamics of multi-particle complexes is of fundamental interest in the study of stochastic chemical systems. In 1976, Masao Doi introduced a Fock space formalism for modeling classical particles. Doi's formalism, howev
Externí odkaz:
http://arxiv.org/abs/2409.01529
Autor:
Ireland, William T., Beeler, Suzannah M., Flores-Bautista, Emanuel, Belliveau, Nathan M., Sweredoski, Michael J., Moradian, Annie, Kinney, Justin B., Phillips, Rob
Advances in DNA sequencing have revolutionized our ability to read genomes. However, even in the most well-studied of organisms, the bacterium ${\it Escherichia coli}$, for $\approx$ 65$\%$ of the promoters we remain completely ignorant of their regu
Externí odkaz:
http://arxiv.org/abs/2001.07396
Autor:
Tareen, Ammar, Kinney, Justin B.
The adoption of deep learning techniques in genomics has been hindered by the difficulty of mechanistically interpreting the models that these techniques produce. In recent years, a variety of post-hoc attribution methods have been proposed for addre
Externí odkaz:
http://arxiv.org/abs/2001.03560
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2021 Oct 01. 118(40), 1-12.
Externí odkaz:
https://www.jstor.org/stable/27075939
Akademický článek
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Publikováno v:
Phys. Rev. Lett. 121, 160605 (2018)
How might a smooth probability distribution be estimated, with accurately quantified uncertainty, from a limited amount of sampled data? Here we describe a field-theoretic approach that addresses this problem remarkably well in one dimension, providi
Externí odkaz:
http://arxiv.org/abs/1804.01932
Publikováno v:
Cell Systems 8 86-93 (2019)
Affinity maturation produces antibodies that bind antigens with high specificity by accumulating mutations in the antibody sequence. Mapping out the antibody-antigen affinity landscape can give us insight into the accessible paths during this rapid e
Externí odkaz:
http://arxiv.org/abs/1712.04000
Autor:
Skalenko, Kyle S., Li, Lingting, Zhang, Yuanchao, Vvedenskaya, Irina O., Winkelman, Jared T., Cope, Alexander L., Taylor, Deanne M., Shah, Premal, Ebright, Richard H., Kinney, Justin B., Zhang, Yu, Nickels, Bryce E.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2021 Jul 01. 118(27), 1-12.
Externí odkaz:
https://www.jstor.org/stable/27052368
Akademický článek
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Autor:
Morrison, Muir J., Kinney, Justin B.
Large complexes of classical particles play central roles in biology, in polymer physics, and in other disciplines. However, physics currently lacks mathematical methods for describing such complexes in terms of component particles, interaction energ
Externí odkaz:
http://arxiv.org/abs/1603.07369