Zobrazeno 1 - 10
of 377
pro vyhledávání: '"Kinji, Ohno"'
Autor:
Nozomi Furukawa, Hiroki Matsui, Hiroaki Sunaga, Kohzo Nagata, Masaaki Hirayama, Hideru Obinata, Tomoyuki Yokoyama, Kinji Ohno, Masahiko Kurabayashi, Norimichi Koitabashi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Titin, a giant sarcomeric protein, regulates diastolic left ventricular (LV) passive stiffness as a molecular spring and could be a therapeutic target for diastolic dysfunction. Sacubitril/valsartan (Sac/Val), an angiotensin receptor neprily
Externí odkaz:
https://doaj.org/article/f568275c3d9b49dea4d6549c5c5d86e5
Autor:
Hiroshi Nishiwaki, Jun Ueyama, Mikako Ito, Tomonari Hamaguchi, Keiichi Takimoto, Tetsuya Maeda, Kenichi Kashihara, Yoshio Tsuboi, Hiroshi Mori, Ken Kurokawa, Masahisa Katsuno, Masaaki Hirayama, Kinji Ohno
Publikováno v:
npj Parkinson's Disease, Vol 10, Iss 1, Pp 1-11 (2024)
Abstract We aimed to identify gut microbial features in Parkinson’s disease (PD) across countries by meta-analyzing our fecal shotgun sequencing dataset of 94 PD patients and 73 controls in Japan with five previously reported datasets from USA, Ger
Externí odkaz:
https://doaj.org/article/dcd4a11c530748f9a4fe08ed7e2c7a9e
Autor:
Ruchen Zhang, Paniz Farshadyeganeh, Bisei Ohkawara, Kazuki Nakajima, Jun-ichi Takeda, Mikako Ito, Shaochuan Zhang, Yuki Miyasaka, Tamio Ohno, Madoka Mori-Yoshimura, Akio Masuda, Kinji Ohno
Publikováno v:
Disease Models & Mechanisms, Vol 17, Iss 8 (2024)
Externí odkaz:
https://doaj.org/article/dd1d6d2ad7d74c9db299f98aace79c6f
Autor:
Yutaro Fuse, Yoshitaka Nagashima, Hiroshi Nishiwaki, Fumiharu Ohka, Yusuke Muramatsu, Yoshio Araki, Yusuke Nishimura, Jumpei Ienaga, Tetsuya Nagatani, Yukio Seki, Kazuhiko Watanabe, Kinji Ohno, Ryuta Saito
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Chronic subdural hematoma (CSDH) often causes neurological deterioration and is treated with hematoma evacuation. This study aimed to assess the feasibility of various machine learning models to preoperatively predict the functional outcome
Externí odkaz:
https://doaj.org/article/8c1145fbaf614d80b6b0ebb5f54641b6
Autor:
Xin‐Ming Shen, Tomohiko Nakata, Seiji Mizuno, Issei Imoto, Duygu Selcen, Kinji Ohno, Andrew G. Engel
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 10, Iss 5, Pp 732-743 (2023)
Abstract Objective To dissect the kinetic defects of acetylcholine receptor (AChR) γ subunit variant in an incomplete form of the Escobar syndrome without pterygium and compare it with those of a variant of corresponding residue in the AChR ε subun
Externí odkaz:
https://doaj.org/article/12fb62f583b14adf8b8977384aad2bd7
Publikováno v:
npj Parkinson's Disease, Vol 9, Iss 1, Pp 1-8 (2023)
Abstract Parkinson’s disease (PD) is pathologically characterized by the abnormal accumulation of α-synuclein fibrils (Lewy bodies) in the substantia nigra and other brain regions, although the role of Lewy bodies remains elusive. Constipation usu
Externí odkaz:
https://doaj.org/article/94847eab5b644a1786d7270dffe7aaca
Autor:
Paniz Farshadyeganeh, Mohammad Nazim, Ruchen Zhang, Bisei Ohkawara, Kazuki Nakajima, Mohammad Alinoor Rahman, Farhana Nasrin, Mikako Ito, Jun-ichi Takeda, Kenji Ohe, Yuki Miyasaka, Tamio Ohno, Akio Masuda, Kinji Ohno
Publikováno v:
iScience, Vol 26, Iss 10, Pp 107746- (2023)
Summary: Glutamine:fructose-6-phosphate transaminase 1 (GFPT1) is the rate-limiting enzyme of the hexosamine biosynthetic pathway (HBP). A 54-bp exon 9 of GFPT1 is specifically included in skeletal and cardiac muscles to generate a long isoform of GF
Externí odkaz:
https://doaj.org/article/3389bd93cb9e4caaa6d1fa76afe19c00
Autor:
Zhizhou Huang, Mikako Ito, Shaochuan Zhang, Takuro Toda, Jun-ichi Takeda, Tomoo Ogi, Kinji Ohno
Publikováno v:
Ecotoxicology and Environmental Safety, Vol 264, Iss , Pp 115482- (2023)
The pervasive weak electromagnetic fields (EMF) inundate the industrialized society, but the biological effects of EMF as weak as 10 µT have been scarcely analyzed. Heat shock proteins (HSPs) are molecular chaperones that mediate a sequential stress
Externí odkaz:
https://doaj.org/article/1c02a5dbff1c4665ae89f11bc10d3249
Publikováno v:
Oxygen, Vol 3, Iss 1, Pp 143-162 (2023)
Over 2000 publications including more than 100 human studies seem to indicate that humans have only recently benefited from or known about the medical effects of H2 within the past 15 years. However, we have unknowingly benefited from H2 since the da
Externí odkaz:
https://doaj.org/article/cff2cd4acd26472a98e4bd9b086a2a1c
Autor:
Itaru Kawashima, Masaki Matsushita, Kenichi Mishima, Yasunari Kamiya, Yusuke Osawa, Bisei Ohkawara, Kinji Ohno, Hiroshi Kitoh, Shiro Imagama
Publikováno v:
BMC Musculoskeletal Disorders, Vol 24, Iss 1, Pp 1-10 (2023)
Abstract Background Postmenopausal osteoporosis is a widespread health concern due to its prevalence among older adults and an associated high risk of fracture. The downregulation of bone regeneration delays fracture healing. Activated fibroblast gro
Externí odkaz:
https://doaj.org/article/5799846324ae40b599c9115aa3054e4e