A fluorescently-tagged tick kinin neuropeptide triggers peristalsis and labels tick midgut muscles.

Autor: Hernandez JR; Department of Entomology, Texas A&M University, College Station, TX, 77843-2475, USA., Xiong C; Department of Entomology, Texas A&M University, College Station, TX, 77843-2475, USA., Pietrantonio PV; Department of Entomology, Texas A&M University, College Station, TX, 77843-2475, USA. p-pietrantonio@tamu.edu.

Publikováno v: Scientific reports [Sci Rep] 2024 May 13; Vol. 14 (1), pp. 10863. Date of Electronic Publication: 2024 May 13.

Kinin B1 receptor modulates glucose homeostasis and physical exercise capacity by altering adrenal catecholamine synthesis and secretion.

Autor: Fernandes Gregnani M; Department of Byophisics, Federal University of São Paulo, Brazil; Max-Delbrück Center for Molecular Medicine (MDC), Robert-Rössle-Str. 10, 13125, Berlin, Germany. Electronic address: fernandes.gregnani@unifesp.br., Budu A; Department of Byophisics, Federal University of São Paulo, Brazil., Batista RO; Department of Byophisics, Federal University of São Paulo, Brazil., Ornellas FH; Department of Byophisics, Federal University of São Paulo, Brazil., Estrela GR; Department of Medicine, Discipline of Nephrology, Federal University of Sao Paulo, São Paulo, Brazil; Department of Clinical and Experimental Oncology, Discipline of Hematology and Hematotherapy, Federal University of São Paulo, 04037002, São Paulo, Brazil., Arruda AC; Department of Byophisics, Federal University of São Paulo, Brazil., Freitas Lima LC; Department of Byophisics, Federal University of São Paulo, Brazil., Kremer JL; Department of Anatomy, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil., Favaroni Mendes LA; Department of Medicine, Discipline of Nephrology, Federal University of Sao Paulo, São Paulo, Brazil., Casarini DE; Department of Medicine, Discipline of Nephrology, Federal University of Sao Paulo, São Paulo, Brazil., Lotfi CFP; Department of Anatomy, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil., Oyama LM; Department of Physiology, Federal University of São Paulo, Brazil., Bader M; Max-Delbrück Center for Molecular Medicine (MDC), Robert-Rössle-Str. 10, 13125, Berlin, Germany; German Center for Cardiovascular Research (DZHK), Partner Site Berlin, 10117, Berlin, Germany; Max Delbrück Center of Molecular Medicine, Charité University Medicine, Charitéplatz 1, 10117, Berlin, Germany; Institute for Biology, University of Lübeck, Ratzeburger Allee 160, 23562, Lübeck, Germany., Araújo RC; Department of Byophisics, Federal University of São Paulo, Brazil.

Publikováno v: Molecular and cellular endocrinology [Mol Cell Endocrinol] 2024 Jan 01; Vol. 579, pp. 112085. Date of Electronic Publication: 2023 Oct 11.

Target-based discovery of antagonists of the tick (Rhipicephalus microplus) kinin receptor identifies small molecules that inhibit midgut contractions.

Autor: Henriques-Santos BM; Department of Entomology, Texas A&M University, College Station, TX, USA., Baker D; Department of Biochemistry and Biophysics, Texas A&M University, College Station, TX, USA., Zhou N; Department of Biochemistry and Biophysics, Texas A&M University, College Station, TX, USA., Snavely T; Department of Biochemistry and Biophysics, Texas A&M University, College Station, TX, USA., Sacchettini JC; Department of Biochemistry and Biophysics, Texas A&M University, College Station, TX, USA., Pietrantonio PV; Department of Entomology, Texas A&M University, College Station, TX, USA.

Publikováno v: Pest management science [Pest Manag Sci] 2024 Oct; Vol. 80 (10), pp. 5168-5179. Date of Electronic Publication: 2024 Jun 20.

Kinins: Locally formed peptides during inflammation with potential use in tissue regeneration.

Autor: Martins L; Division of Medical Sciences, Laboratory of Transcriptional Regulation, Institute of Medical Biology of Polish Academy of Sciences (IMB-PAN), 3a Tylna St., 90-364, Łódź, Poland. lmartin@cbm.pan.pl.; Center for Research and Molecular Diagnosis of Genetic Diseases, Federal University of São Paulo, Rua Pedro de Toledo 669, 9th floor, São Paulo, 04039032, Brazil. lmartin@cbm.pan.pl.; Department of Biochemistry and Molecular Biology, Federal University of São Paulo, Rua Três de Maio 100, 4th floor, São Paulo, 04044-020, Brazil. lmartin@cbm.pan.pl., Bader M; Max-Delbrück Center for Molecular Medicine (MDC), Robert-Rössle-Str. 10, 13125, Berlin, Germany.; Institute for Biology, University of Lübeck, Ratzeburger Allee 160, 23562, Lübeck, Germany.; Charité University Medicine Berlin, Charitéplatz 1, 10117, Berlin, Germany.; German Center for Cardiovascular Research (DZHK), Potsdamer Str. 58, 10785, Berlin, Germany., Pesquero JB; Center for Research and Molecular Diagnosis of Genetic Diseases, Federal University of São Paulo, Rua Pedro de Toledo 669, 9th floor, São Paulo, 04039032, Brazil.; Department of Biophysics, Federal University of São Paulo, Rua Botucatu 862, 6th floor, São Paulo, 04023-062, Brazil.

Publikováno v: Inflammation research : official journal of the European Histamine Research Society ... [et al.] [Inflamm Res] 2023 Nov; Vol. 72 (10-11), pp. 1957-1963. Date of Electronic Publication: 2023 Sep 26.

Kallikrein inhibitors for angioedema: the progress of preclinical and early phase studies.

Autor: Farkas H; Hungarian Angioedema Center of Reference and Excellence, Department of Internal, Medicine and Haematology, Semmelweis University, Budapest, Hungary., Balla Z; Hungarian Angioedema Center of Reference and Excellence, Department of Internal, Medicine and Haematology, Semmelweis University, Budapest, Hungary.; HNO-Praxis Schaffhausen, Schaffhausen, Switzerland.

Publikováno v: Expert opinion on investigational drugs [Expert Opin Investig Drugs] 2024 Mar; Vol. 33 (3), pp. 191-200. Date of Electronic Publication: 2024 Feb 26.