Exploiting metabolic vulnerabilities after anti-VEGF antibody therapy in ovarian cancer.

Autor: Glassman D; Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Unit 1362, 1515 Holcombe Blvd, Houston, TX 77030, USA., Kim MS; Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Unit 1362, 1515 Holcombe Blvd, Houston, TX 77030, USA., Spradlin M; Department of Chemistry, The University of Texas at Austin, Austin, TX, USA.; Department of Surgery, Baylor College of Medicine, Houston, TX, USA., Badal S; Department of Chemistry, The University of Texas at Austin, Austin, TX, USA., Taki M; Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Unit 1362, 1515 Holcombe Blvd, Houston, TX 77030, USA., Bhattacharya P; Department of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Dutta P; Department of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Kingsley CV; Department of Cancer Systems Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Foster KI; Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Unit 1362, 1515 Holcombe Blvd, Houston, TX 77030, USA., Animasahun O; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA.; Department of Chemical Engineering, University of Michigan, Ann Arbor, MI, USA., Jeon JH; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA., Achreja A; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA., Jayaraman A; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA., Kumar P; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA., Nenwani M; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA., Wuchu F; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA., Bayraktar E; Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Unit 1362, 1515 Holcombe Blvd, Houston, TX 77030, USA., Wu Y; Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Unit 1362, 1515 Holcombe Blvd, Houston, TX 77030, USA., Stur E; Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Unit 1362, 1515 Holcombe Blvd, Houston, TX 77030, USA., Mangala L; Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Unit 1362, 1515 Holcombe Blvd, Houston, TX 77030, USA., Lee S; Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Unit 1362, 1515 Holcombe Blvd, Houston, TX 77030, USA.; Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Yap TA; Department of Investigational Cancer Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.; The Institute for Applied Cancer Science, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Westin SN; Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Unit 1362, 1515 Holcombe Blvd, Houston, TX 77030, USA., Eberlin LS; Department of Chemistry, The University of Texas at Austin, Austin, TX, USA.; Department of Surgery, Baylor College of Medicine, Houston, TX, USA., Nagrath D; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, USA., Sood AK; Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Unit 1362, 1515 Holcombe Blvd, Houston, TX 77030, USA.

Publikováno v: IScience [iScience] 2023 Jan 19; Vol. 26 (2), pp. 106020. Date of Electronic Publication: 2023 Jan 19 (Print Publication: 2023).

Technical Note: Histological validation of anatomical imaging for breast modeling using a novel cryo-microtome.

Autor: Sen A; Department of Imaging Physics, University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Fowlkes NW; Department of Veterinary Medicine & Surgery, University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Kingsley CV; Department of Imaging Physics, University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Kulp AM; Department of Imaging Physics, University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Huynh T; Department of Veterinary Medicine & Surgery, University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Willis BJ; Department of Imaging Physics, University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Brewer Savannah KJ; Department of Imaging Physics, University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Bordes MCA; Department of Plastic Surgery, University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Hwang KP; Department of Imaging Physics, University of Texas MD Anderson Cancer Center, Houston, Texas, USA., McCulloch MM; Department of Imaging Physics, University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Stafford RJ; Department of Imaging Physics, University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Contreras A; Department of Pathology, University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Reece G; Department of Plastic Surgery, University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Brock KK; Department of Imaging Physics, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.; Department of Radiation Physics, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.

Publikováno v: Medical physics [Med Phys] 2021 Nov; Vol. 48 (11), pp. 7323-7332. Date of Electronic Publication: 2021 Oct 11.

Selective EGLN Inhibition Enables Ablative Radiotherapy and Improves Survival in Unresectable Pancreatic Cancer.

Autor: Fujimoto TN; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Colbert LE; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Huang Y; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Molkentine JM; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Deorukhkar A; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Baseler L; Department of Veterinary Medicine & Surgery, UT MD Anderson Cancer Center, Houston, Texas., de la Cruz Bonilla; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Yu M; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Lin D; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Gupta S; Department of Pathology, UT MD Anderson Cancer Center, Houston, Texas.; Department of Translational Molecular Pathology, UT MD Anderson Cancer Center, Houston, Texas., Cabeceiras PK; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Kingsley CV; Department of Imaging Physics, UT MD Anderson Cancer Center, Houston, Texas., Tailor RC; Department of Radiation Physics, UT MD Anderson Cancer Center, Houston, Texas., Sawakuchi GO; Department of Radiation Physics, UT MD Anderson Cancer Center, Houston, Texas., Koay EJ; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Piwnica-Worms H; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas., Maitra A; Department of Pathology, UT MD Anderson Cancer Center, Houston, Texas.; Department of Translational Molecular Pathology, UT MD Anderson Cancer Center, Houston, Texas., Taniguchi CM; Department of Experimental Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas. ctaniguchi@mdanderson.org.; Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

Publikováno v: Cancer research [Cancer Res] 2019 May 01; Vol. 79 (9), pp. 2327-2338.

Radiation-induced lung toxicity in mice irradiated in a strong magnetic field.

Autor: Rubinstein AE; Department of Diagnostic and Interventional Imaging, UTHealth McGovern Medical School, Houston, Texas, United States of America., Gay S; Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America., Peterson CB; Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America., Kingsley CV; Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America., Tailor RC; Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America., Pollard-Larkin JM; Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America., Melancon AD; Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America., Followill DS; Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America., Court LE; Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.; Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.

Publikováno v: PloS one [PLoS One] 2018 Nov 16; Vol. 13 (11), pp. e0205803. Date of Electronic Publication: 2018 Nov 16 (Print Publication: 2018).

Differential Effects of EGFL6 on Tumor versus Wound Angiogenesis.

Autor: Noh K; Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Gene Therapy Research Unit, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea., Mangala LS; Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Center for RNA Interference and Non-Coding RNA, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Han HD; Department of Immunology, School of Medicine, Konkuk University, Chungju 380-701, South Korea., Zhang N; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA., Pradeep S; Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Obstetrics and Gynecology, Medical College of Wisconsin, Milwaukee, WI 53226, USA., Wu SY; Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Ma S; Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Mora E; Department of Surgery, University of Puerto Rico, San Juan 00936, Puerto Rico; University of Puerto Rico Comprehensive Cancer Center, San Juan 00936, Puerto Rico; Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77584, USA., Rupaimoole R; Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Jiang D; Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Center for RNA Interference and Non-Coding RNA, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Wen Y; Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Shahzad MMK; Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Lyons Y; Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Cho M; Department of Benign Hematology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Hu W; Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Nagaraja AS; Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Haemmerle M; Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Mak CSL; Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Chen X; Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Gharpure KM; Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Deng H; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA., Xiong W; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA., Kingsley CV; Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Liu J; Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Jennings N; Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Birrer MJ; University of Alabama Comprehensive Cancer Center, Birmingham, AL 35294, USA., Bouchard RR; Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Lopez-Berestein G; Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Center for RNA Interference and Non-Coding RNA, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., Coleman RL; Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA., An Z; Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA., Sood AK; Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Center for RNA Interference and Non-Coding RNA, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Electronic address: asood@mdanderson.orgSummary.

Publikováno v: Cell reports [Cell Rep] 2017 Dec 05; Vol. 21 (10), pp. 2785-2795.