Canvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space

Autor: Kearney, SE, Zahoránszky-Köhalmi, G, Brimacombe, KR, Henderson, MJ, Lynch, C, Zhao, T, Wan, KK, Itkin, Z, Dillon, C, Shen, M, Cheff, DM, Lee, TD, Bougie, D, Cheng, K, Coussens, NP, Dorjsuren, D, Eastman, RT, Huang, R, Iannotti, MJ, Karavadhi, S, Klumpp-Thomas, C, Roth, JS, Sakamuru, S, Sun, W, Titus, SA, Yasgar, A, Zhang, YQ, Zhao, J, Andrade, RB, Brown, MK, Burns, NZ, Cha, JK, Mevers, EE, Clardy, J, Clement, JA, Crooks, PA, Cuny, GD, Ganor, J, Moreno, J, Morrill, LA, Picazo, E, Susick, RB, Garg, NK, Goess, BC, Grossman, RB, Hughes, CC, Johnston, JN, Joullie, MM, Kinghorn, AD, Kingston, DGI, Krische, MJ, Kwon, O, Maimone, TJ, Majumdar, S, Maloney, KN, Mohamed, E, Murphy, BT, Nagorny, P, Olson, DE, Overman, LE, Brown, LE, Snyder, JK, Porco, JA, Rivas, F, Ross, SA, Sarpong, R, Sharma, I, Shaw, JT, Xu, Z, Shen, B, Shi, W, Stephenson, CRJ, Verano, AL, Tan, DS, Tang, Y, Taylor, RE, Thomson, RJ, Vosburg, DA, Wu, J, Wuest, WM, Zakarian, A, Zhang, Y, Ren, T, Zuo, Z, Inglese, J, Michael, S, Simeonov, A, Zheng, W, Shinn, P, Jadhav, A, Boxer, MB, Hall, MD, Xia, M, Guha, R

Publikováno v: Kearney, SE; Zahoránszky-Köhalmi, G; Brimacombe, KR; Henderson, MJ; Lynch, C; Zhao, T; et al.(2018). Canvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space. ACS Central Science, 4(12), 1727-1741. doi: 10.1021/acscentsci.8b00747. UC Davis: Retrieved from: http://www.escholarship.org/uc/item/0vt658wh

Copyright © 2018 American Chemical Society. Natural products and their derivatives continue to be wellsprings of nascent therapeutic potential. However, many laboratories have limited resources for biological evaluation, leaving their previously iso

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::8f3748e2a73a8da6abbc39abbd196dad
http://www.escholarship.org/uc/item/0vt658wh

Special Issue in Honor of Norman R. Farnsworth

Autor: Kinghorn Ad, Cordell Ga, Harry H. S. Fong

Publikováno v: Journal of Natural Products. 69:311-313

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::154d023d22c6cfee24d47adbd11d493e
https://doi.org/10.1021/np068000l

Aromatase inhibitors fromIsodon excisus var.coreanus

Autor: Hyeh Jean Jeong, Hohyun Kim, John M. Pezzuto, Kinghorn Ad, Il Hyuk Kim, Leng Chee Chang

Publikováno v: Archives of Pharmacal Research. 23:243-245

The diethyl ether extract of Isodon excisus var. coreanus exhibited significant inhibitory activity in aromatase assay. Bioactivity-guided fractionation of the extract led to the isolation of three active compounds: inflexin (ent-1alpha-hydroxy-3beta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b0fe7e41a7830fe54df2c01f4500365
https://doi.org/10.1007/bf02976453

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