Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Kinga Nyíri"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract The excision and replication, thus the life cycle of pathogenicity islands in staphylococci are regulated by Stl master repressors that form strong dimers. It has been recently shown that SaPIbov1-Stl dimers are separated during the activati
Externí odkaz:
https://doaj.org/article/e02ecd78da2f454a912476df1e300857
Autor:
Ivan Ranđelović, Kinga Nyíri, Gergely Koppány, Marcell Baranyi, József Tóvári, Attila Kigyós, József Tímár, Beáta G. Vértessy, Vince Grolmusz
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 5, p 2572 (2024)
Mutated genes may lead to cancer development in numerous tissues. While more than 600 cancer-causing genes are known today, some of the most widespread mutations are connected to the RAS gene; RAS mutations are found in approximately 25% of all human
Externí odkaz:
https://doaj.org/article/7529b61e5cd54d1f95b30df68f2d8c7d
Autor:
Judit Eszter Szabó, Kinga Nyíri, Dániel Andrási, Judit Matejka, Olivér Ozahonics, Beáta Vértessy
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Recently it was proposed that the redox status of cysteines acts as a redox switch to regulate both the oligomeric status and the activity of human dUTPase. In a separate report, a human dUTPase point mutation, resulting in a tyrosine to cys
Externí odkaz:
https://doaj.org/article/e2ca105caedc490383b7eed748bef8b8
Autor:
Judit Eszter Szabó, Kinga Nyíri, Dániel Andrási, Judit Matejka, Olivér Ozohanics, Beáta Vértessy
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/668d45028132414fafee5b780bdb89a6
Autor:
Kinga Nyíri, Matthew J. Harris, Judit Matejka, Olivér Ozohanics, Károly Vékey, Antoni J. Borysik, Beáta G. Vértessy
Publikováno v:
Biomolecules, Vol 9, Iss 9, p 488 (2019)
The dUTPase enzyme family plays an essential role in maintaining the genome integrity and are represented by two distinct classes of proteins; the β-pleated homotrimeric and the all-α homodimeric dUTPases. Representatives of both trimeric and dimer
Externí odkaz:
https://doaj.org/article/fae8e4d82df44a7293d592ac40230cae
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0158793 (2016)
The regulation model of the Staphylococcus aureus pathogenicity island SaPIbov1 transfer was recently reported. The repressor protein Stl obstructs the expression of SaPI proteins Str and Xis, latter which is responsible for mobilization initiation.
Externí odkaz:
https://doaj.org/article/4f9bfc5ba9274394b2aae1aba0055906
Autor:
Éva Viola Surányi, Rita Hírmondó, Kinga Nyíri, Szilvia Tarjányi, Bianka Kőhegyi, Judit Tóth, Beáta G. Vértessy
Publikováno v:
Viruses, Vol 10, Iss 4, p 168 (2018)
Pathogenicity islands of Staphylococcus aureus are under the strong control of helper phages, where regulation is communicated at the gene expression level via a family of specific repressor proteins. The repressor proteins are crucial to phage-host
Externí odkaz:
https://doaj.org/article/c2665943ec8c40499583152a2c825787
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0139086 (2015)
Horizontal transfer of mobile genetic elements within Staphylococci is of high biomedical significance as such elements are frequently responsible for virulence and toxic effects. Staphylococcus-encoded repressor proteins regulate the replication of
Externí odkaz:
https://doaj.org/article/cd829d8506d84f60acccd45b8f4b916c
Ras-positive cancer constitutes a major challenge for medical treatment. Hot spot residues Gly12, Gly13 and Gln61 constitute the majority of oncogenic mutations which are associated with detrimental clinical prognosis. Here we pre-sent a two-step mec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1baab5c35be2b67cc3752c137156eb2d
https://doi.org/10.26434/chemrxiv-2022-ttt09-v2
https://doi.org/10.26434/chemrxiv-2022-ttt09-v2
Autor:
Zoltán Orgován, Nikolett Péczka, László Petri, Péter Ábrányi-Balogh, Ivan Ranđelović, Szilárd Tóth, Gergely Szakács, Kinga Nyíri, Beáta Vértessy, Gyula Pálfy, István Vida, András Perczel, József Tóvári, György M. Keserű
Publikováno v:
European Journal of Medicinal Chemistry. 250:115212