Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Kinga Mieczkowska"'
Autor:
Maria Winiewska-Szajewska, Honorata Czapinska, Magdalena Kaus-Drobek, Anna Fricke, Kinga Mieczkowska, Michał Dadlez, Matthias Bochtler, Jarosław Poznański
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract CK2 is a member of the CMGC group of eukaryotic protein kinases and a cancer drug target. It can be efficiently inhibited by halogenated benzotriazoles and benzimidazoles. Depending on the scaffold, substitution pattern, and pH, these compou
Externí odkaz:
https://doaj.org/article/89313d26965c4bf7973f9706ac44fdf1
Autor:
Maria Bretner, Ewa Marzec, Jarosław Poznański, Kinga Mieczkowska, Krzysztof Woźniak, Damian Trzybiński, Sławomir Kasperowicz, Agnieszka M. Maciejewska
Publikováno v:
IUBMB lifeREFERENCES. 72(6)
A series of chlorine-substituted benzotriazole derivatives, representing all possible substitution patterns of halogen atoms attached to the benzotriazole benzene ring, were synthetized as potential inhibitors of human protein kinase CK2. Basic ADME
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb6e900d360711baeac989e4388054ae
https://pubmed.ncbi.nlm.nih.gov/32162783
https://pubmed.ncbi.nlm.nih.gov/32162783
Autor:
Ewa Bugajska, Kinga Mieczkowska, Sławomir Kasperowicz, Jarosław Poznański, Anna Szymaniec-Rutkowska, Agnieszka M. Maciejewska
Publikováno v:
Journal of Molecular Liquids. 293:111527
Halogenated heterocyclic ligands are widely used as the potent and frequently selective inhibitors of protein kinases. However, the exact contribution of the hydrophobic solvation of a free ligand is rarely accounted for the balance of interactions c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e458a3e340529059168566f0dd9cafc2
https://doi.org/10.1016/j.molliq.2019.111527
https://doi.org/10.1016/j.molliq.2019.111527
Autor:
Kinga Mieczkowska, Miroslav Kašpar, Vladimíra Novotná, Damian Pociecha, Věra Hamplová, Attila Domján, Katalin Fodor-Csorba
Publikováno v:
Liquid Crystals. 39:1252-1260
The synthesis and mesomorphic properties of new non-symmetrical bent-shaped compounds containing a chiral moiety are reported. These materials were built up from 3-hydroxybenzoic acid as a central unit with a chiral terminal group derived from lactic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::045735281ee9e9fe8fc60ceaa6ba8e25
https://doi.org/10.1080/02678292.2012.714485
https://doi.org/10.1080/02678292.2012.714485