Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Kinga Mieczkowska"'
Autor:
Maria Winiewska-Szajewska, Honorata Czapinska, Magdalena Kaus-Drobek, Anna Fricke, Kinga Mieczkowska, Michał Dadlez, Matthias Bochtler, Jarosław Poznański
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract CK2 is a member of the CMGC group of eukaryotic protein kinases and a cancer drug target. It can be efficiently inhibited by halogenated benzotriazoles and benzimidazoles. Depending on the scaffold, substitution pattern, and pH, these compou
Externí odkaz:
https://doaj.org/article/89313d26965c4bf7973f9706ac44fdf1
Autor:
Maria Bretner, Ewa Marzec, Jarosław Poznański, Kinga Mieczkowska, Krzysztof Woźniak, Damian Trzybiński, Sławomir Kasperowicz, Agnieszka M. Maciejewska
Publikováno v:
IUBMB lifeREFERENCES. 72(6)
A series of chlorine-substituted benzotriazole derivatives, representing all possible substitution patterns of halogen atoms attached to the benzotriazole benzene ring, were synthetized as potential inhibitors of human protein kinase CK2. Basic ADME
Autor:
Ewa Bugajska, Kinga Mieczkowska, Sławomir Kasperowicz, Jarosław Poznański, Anna Szymaniec-Rutkowska, Agnieszka M. Maciejewska
Publikováno v:
Journal of Molecular Liquids. 293:111527
Halogenated heterocyclic ligands are widely used as the potent and frequently selective inhibitors of protein kinases. However, the exact contribution of the hydrophobic solvation of a free ligand is rarely accounted for the balance of interactions c
Autor:
Kinga Mieczkowska, Miroslav Kašpar, Vladimíra Novotná, Damian Pociecha, Věra Hamplová, Attila Domján, Katalin Fodor-Csorba
Publikováno v:
Liquid Crystals. 39:1252-1260
The synthesis and mesomorphic properties of new non-symmetrical bent-shaped compounds containing a chiral moiety are reported. These materials were built up from 3-hydroxybenzoic acid as a central unit with a chiral terminal group derived from lactic
Autor:
Winiewska-Szajewska, Maria1,2 (AUTHOR) mwin@ibb.waw.pl, Czapinska, Honorata1,3 (AUTHOR), Kaus-Drobek, Magdalena1 (AUTHOR), Fricke, Anna1,3 (AUTHOR), Mieczkowska, Kinga1 (AUTHOR), Dadlez, Michał1 (AUTHOR), Bochtler, Matthias1,3 (AUTHOR), Poznański, Jarosław1 (AUTHOR) jarek@ibb.waw.pl
Publikováno v:
Scientific Reports. 11/8/2022, Vol. 12 Issue 1, p1-14. 14p.
Autor:
Kasperowicz, Sławomir, Marzec, Ewa, Maciejewska, Agnieszka M., Trzybiński, Damian, Bretner, Maria, Woźniak, Krzysztof, Poznański, Jarosław, Mieczkowska, Kinga
Publikováno v:
IUBMB Life; Jun2020, Vol. 72 Issue 6, p1211-1219, 9p