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pro vyhledávání: '"Kinga Bednarz"'
Publikováno v:
Life, Vol 14, Iss 1, p 127 (2024)
Kynurenic acid is a tryptophan (Trp) metabolite formed along the kynurenine (KYN) pathway in the brain and in peripheral tissues. The disturbed formation of kynurenic acid, which targets glutamate-mediated neurotransmission, GPR35, and aryl hydrocarb
Externí odkaz:
https://doaj.org/article/bfdd40de7daf46c4833978f613ed6ade
Autor:
Marta Malczewska, Kamil Kośmider, Kinga Bednarz, Katarzyna Ostapińska, Monika Lejman, Joanna Zawitkowska
Publikováno v:
Cancers. 14(8)
Acute lymphoblastic leukemia is the most common blood cancer in pediatric patients. There has been enormous progress in ALL treatment in recent years, which is reflected by the increase in the 5-year OS from 57% in the 1970s to up to 96% in the most
Publikováno v:
Toxicology and applied pharmacology. 434
Cardiovascular toxicity represents one of the most common reasons for clinical trial failure. Consequently, early identification of novel cardioprotective strategies could prevent the later-stage drug-induced cardiac side effects. The use of zebrafis
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 9827, p 9827 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 9827, p 9827 (2021)
Targeted therapy has revolutionized the treatment of poor-prognosis pediatric acute lymphoblastic leukemia (ALL) with specific genetic abnormalities. It is still being described as a new landmark therapeutic approach. The main purpose of the use of m