Zobrazeno 1 - 10
of 73
pro vyhledávání: '"King-Song Jeng"'
Publikováno v:
mBio, Vol 8, Iss 3 (2017)
ABSTRACT Influenza A virus (IAV) RNA segments are individually packaged with viral nucleoprotein (NP) and RNA polymerases to form a viral ribonucleoprotein (vRNP) complex. We previously reported that NP is a monoubiquitinated protein which can be deu
Externí odkaz:
https://doaj.org/article/79ef6de50d044801bd1ebc872cca3764
Autor:
Chao-Kuen Lai, Vikas Saxena, Chung-Hsin Tseng, King-Song Jeng, Michinori Kohara, Michael M C Lai
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e99022 (2014)
Nonstructural protein 5A (NS5A) of hepatitis C virus (HCV) serves dual functions in viral RNA replication and virus assembly. Here, we demonstrate that HCV replication complex along with NS5A and Core protein was transported to the lipid droplet (LD)
Externí odkaz:
https://doaj.org/article/a862cbf962884688b8005a3ba4743feb
Publikováno v:
PLoS Pathogens, Vol 8, Iss 6, p e1002766 (2012)
For Hepatitis C virus (HCV), initiation of translation is cap-independently mediated by its internal ribosome entry site (IRES). Unlike other IRES-containing viruses that shut off host cap-dependent translation, translation of HCV coexists with that
Externí odkaz:
https://doaj.org/article/36f9ad27b6f14032ad4c6c7f57925acc
Autor:
Ming-Hsiang Hong, Yu-Chi Chou, Yi-Chieh Wu, Kuen-Nan Tsai, Cheng-po Hu, King-Song Jeng, Mong-Liang Chen, Chungming Chang
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30360 (2012)
Several studies have demonstrated that cytokine-mediated noncytopathic suppression of hepatitis B virus (HBV) replication may provide an alternative therapeutic strategy for the treatment of chronic hepatitis B infection. In our previous study, we sh
Externí odkaz:
https://doaj.org/article/bef846d554fd441687f5a5f5da3b6880
Publikováno v:
Journal of Virology
Influenza A virus (IAV) replication relies on an intricate interaction between virus and host cells. How the cellular proteins are usurped for IAV replication remains largely obscure. The aim of this study was to search for novel and potential cellul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::265ba4813e238681c7e4d56a9a085050
https://pubmed.ncbi.nlm.nih.gov/28768860
https://pubmed.ncbi.nlm.nih.gov/28768860
Publikováno v:
Journal of Virology
Sequences in the 5′ untranslated region (5′UTR) of hepatitis C virus (HCV) RNA is important for modulating both translation and RNA replication. The translation of the HCV genome depends on an internal ribosome entry site (IRES) located within th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77bc9fa01da70c8039076b95095f7e08
Publikováno v:
Journal of Virology. 84:11590-11598
Hepatitis C virus (HCV) assembly is known to occur in juxtaposition to lipid droplets, but the mechanisms of nascent virion transport and release remain poorly understood. Here we demonstrate that HCV core protein targets to early and late endosomes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c3b9b0397a4558ef0260ea0650a8b4f
https://doi.org/10.1128/jvi.00587-10
https://doi.org/10.1128/jvi.00587-10
Publikováno v:
The EMBO Journal
Influenza A virus RNA replication requires an intricate regulatory network involving viral and cellular proteins. In this study, we examined the roles of cellular ubiquitinating/deubiquitinating enzymes (DUBs). We observed that downregulation of a ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e4dbaa07479c63d34272e477e47315e
https://doi.org/10.1038/emboj.2010.250
https://doi.org/10.1038/emboj.2010.250
Publikováno v:
Journal of Virology. 82:9409-9416
Hepatitis delta virus (HDV) contains a viroid-like, 1.7-kb circular RNA genome, which replicates via a double-rolling-circle model. However, the exact mechanism involved in HDV genome RNA replication and subgenomic mRNA transcription is still unclear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a0004627e2dc87d77d217f7be69fe20
https://doi.org/10.1128/jvi.00428-08
https://doi.org/10.1128/jvi.00428-08
Autor:
Jim-Min Fang, Jiun-Jie Shie, King-Song Jeng, Yih-Shyun E. Cheng, Shi-Yun Wang, Nigel J. Temperton, Ching-Yao Su, Chi-Huey Wong
Publikováno v:
Antiviral Research. 79:199-205
For the treatment of influenza virus infections, neuraminidase inhibitors (NAIs) that prevent the release of virus particles have been effective against most influenza strains. Several neuraminidase (NA) assays are available for the evaluation of NAI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5863e885617f99a1f07308fb882772bd
https://doi.org/10.1016/j.antiviral.2008.03.002
https://doi.org/10.1016/j.antiviral.2008.03.002