Zobrazeno 1 - 10
of 12
pro vyhledávání: '"King Yiu Lee"'
Autor:
King Yiu Lee, Kathy Yuen Yee Chan, Kam Sze Tsang, Yang Chao Chen, Hsiang-fu Kung, Pak Cheung Ng, Chi Kong Li, Kam Tong Leung, Karen Li
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92706 (2014)
Makorin-2 (MKRN2) is a highly conserved protein and yet its functions are largely unknown. We investigated the expression levels of MKRN2 and RAF1 in normal and malignant hematopoietic cells, and leukemia cell lines. We also attempted to delineate th
Externí odkaz:
https://doaj.org/article/3223c5ade40e49be940e194e5250548c
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e35799 (2012)
To establish a genetic tool for conditional deletion or expression of gene in neurons in a temporally controlled manner, we generated a transgenic mouse (NSE-MerCreMer), which expressed a tamoxifen inducible type of Cre recombinase specifically in ne
Externí odkaz:
https://doaj.org/article/3235addef0fc4c1abb4ae7eb0b926672
Autor:
Karen Li, Ka Fai To, Ellen Ngar Yun Poon, Margaret H.L. Ng, Tak Yeung Leung, Han Wang, Chi Zhang, King Yiu Lee, Kam Tong Leung, Chun Chen, Cheuk-Kwong Lee, Patrick Ming-Kuen Tang, Wing Hei Ng, Alex Wing Kwan Leung, Patrick Man Pan Yuen, Kathy Yuen Yee Chan, Chi Chiu Wang, Chi Kong Li, Pak Cheung Ng, Yorky Tsin Sik Wong, Xiao-Bing Zhang, Siu Ping Fok, Wei Kang, Bo Feng, Hugh Simon Lam
Publikováno v:
Blood Advances
Key Points Specific R4 RGS members are expressed in human HSPCs and regulated by the SDF-1/CXCR4 axis.RGS1/13/16 suppress HSPC engraftment, SDF-1 signaling, and key effectors of stem cell trafficking/maintenance.
Visual Abstract
Homing and
Visual Abstract
Homing and
Autor:
Tsin Sik Wong, King Yiu Lee, Chi Kong Li, Xiao-Bing Zhang, Frankie W.T. Cheng, Kam Tong Leung, Karen Li, Ronald Chi Chiu Wang, Kathy Yuen Yee Chan
Publikováno v:
Blood. 134:1927-1927
Members of the Regulators of G-protein Signaling (RGS) are GTPase-accelerating proteins and have been implicated in SDF-1-directed trafficking of mature hematopoietic cells. However, their roles in hematopoietic stem and progenitor cells (HSPC) remai
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 5, p e35799 (2012)
PLoS ONE, Vol 7, Iss 5, p e35799 (2012)
To establish a genetic tool for conditional deletion or expression of gene in neurons in a temporally controlled manner, we generated a transgenic mouse (NSE-MerCreMer), which expressed a tamoxifen inducible type of Cre recombinase specifically in ne
Autor:
Kathy Yuen Yee Chan, Kam Sze Tsang, King Yiu Lee, Benny Shu Pan Fong, Audrey Carmen Lam, Pak Cheung Ng, Chi Chiu Wang, Hsiang-Fu Kung, Tze Kin Lau, Karen Li, Chi Kong Li
Publikováno v:
Stem cells and development. 20(1)
Hematopoiesis during mammalian embryonic development has been perceived as a migratory phenomenon, from the yolk sac blood island to the aorta-gonad-mesonephros (AGM) region, fetal liver (FL), and subsequently, the fetal bone marrow. In this study, w
Publikováno v:
Biochimica et biophysica acta. 1627(1)
The RET protooncogene encodes for a transmembrane receptor tyrosine kinase and plays a crucial role in nephrogenesis and the enteric nervous system (ENS) development. Alternative splicing at the 3′ end of the RET gene generates 3′ splicing varian
Autor:
Karen Li, Chi Kong Li, Kathy Yuen Yee Chan, King Yiu Lee, Hsiang-Fu Kung, Kam Tong Leung, Pak Cheung Ng, Kam Sze Tsang, Yangchao Chen
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e92706 (2014)
PLoS ONE
PLoS ONE
Makorin-2 (MKRN2) is a highly conserved protein and yet its functions are largely unknown. We investigated the expression levels of MKRN2 and RAF1 in normal and malignant hematopoietic cells, and leukemia cell lines. We also attempted to delineate th