Zobrazeno 1 - 10
of 97
pro vyhledávání: '"King Yip Cheng"'
Autor:
Kelvin Ka-lok Wu, Xiaofan Xu, Manyin Wu, Xiaomu Li, Moinul Hoque, Gloria Hoi Yee Li, Qizhou Lian, Kekao Long, Tongxi Zhou, Hailong Piao, Aimin Xu, Hannah Xiaoyan Hui, Kenneth King-yip Cheng
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract M1 macrophages induce protective immunity against infection, but also contribute to metabolic and inflammatory diseases. Here we show that the E3 ubiquitin ligase, MDM2, promotes the glycolytic and inflammatory activities of M1 macrophage by
Externí odkaz:
https://doaj.org/article/a3cecd46ad844e0ca36f7a957405e747
Autor:
Huan Zhang, Tung-Ting Sham, Chang Li, Yi Wang, Chen-yu Li, Kenneth King-yip Cheng, Chun-Pang So, Yu-yin Huang, Shun-Wan Chan, Daniel Kam-Wah Mok
Publikováno v:
Pharmacological Research - Modern Chinese Medicine, Vol 9, Iss , Pp 100335- (2023)
Background: Polygoni Cuspidati Rhizoma et Radix (PCRR; the root and rhizome of Polygonum cuspidatum Sieb. et Zucc) has long been used to treat atherosclerosis, gastrointestinal disorders, and liver disease. However, the underlying mechanism of PCRR a
Externí odkaz:
https://doaj.org/article/67347f8277964252a48d0c2346003c76
Autor:
Zhang, Huan, Sham, Tung-Ting, Li, Chang, Wang, Yi, Li, Chen-yu, King-yip Cheng, Kenneth, So, Chun-Pang, Huang, Yu-yin, Chan, Shun-Wan, Mok, Daniel Kam-Wah
Publikováno v:
In Pharmacological Research - Modern Chinese Medicine December 2023 9
Autor:
Zhuohao Liu, Jiayi Zhou, Xinzhi Yang, Yuchen Liu, Chang Zou, Wen Lv, Cheng Chen, Kenneth King-yip Cheng, Tao Chen, Lung-Ji Chang, Dinglan Wu, Jie Mao
Publikováno v:
Molecular Cancer, Vol 22, Iss 1, Pp 1-15 (2023)
Abstract Background This study aimed to validate whether infusion of GD2-specific fourth-generation safety-designed chimeric antigen receptor (4SCAR)-T cells is safe and whether CAR-T cells exert anti-glioblastoma (GBM) activity. Methods A total of e
Externí odkaz:
https://doaj.org/article/9c4170e5fac24876802eeade1e6638be
Autor:
Philip Hallenborg, Benjamin Anderschou Holbech Jensen, Even Fjære, Rasmus Koefoed Petersen, Mohammed-Samir Belmaâti, Sarah Søndergård Rasmussen, Jon Petur Gunnarsson, Pernille Lauritzen, Kenneth King Yip Cheng, Martin Hermansson, Si Brask Sonne, Christer S. Ejsing, Aimin Xu, Irina Kratchmarova, Marcus Krüger, Lise Madsen, Karsten Kristiansen, Blagoy Blagoev
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract The intimate association between obesity and type II diabetes urges for a deeper understanding of adipocyte function. We and others have previously delineated a role for the tumor suppressor p53 in adipocyte biology. Here, we show that mice
Externí odkaz:
https://doaj.org/article/40be2ce071a64faf8d38428ae1f155cb
Autor:
Kelvin Ka Lok Wu, KeKao Long, Huige Lin, Parco Ming Fai Siu, Ruby Lai Chong Hoo, Dewei Ye, Aimin Xu, Kenneth King Yip Cheng
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Inflammasome regulation is not fully understood. Here the authors show that the early endosomal APPL1-Rab5 axis removes damaged mitochondria and then restricts the inflammasome response in macrophages, alleviating the inflammatory diseases.
Externí odkaz:
https://doaj.org/article/acd1f474dbe44e05886bd6aede2b54b2
Autor:
Koon-Yee Lee, Grace, Chun-Ming Au, Philip, Hoi-Yee Li, Gloria, Chan, Marcus, Li, Hang-Long, Man-Yung Cheung, Bernard, Chi-Kei Wong, Ian, Ho-Fun Lee, Victor, Mok, James, Hon-Kei Yip, Benjamin, King-Yip Cheng, Kenneth, Wu, Chih-Hsing, Cheung, Ching-Lung
Publikováno v:
In Osteoporosis and Sarcopenia March 2021 7 Supplement 1:S19-S27
Autor:
Xinzhi Yang, Jiangang Liu, Chenci Wang, Kenneth King-yip Cheng, Hongchao Xu, Qingzhong Li, Tian Hua, Xue Jiang, Lili Sheng, Jie Mao, Zhuohao Liu
Publikováno v:
Oncogenesis, Vol 10, Iss 2, Pp 1-13 (2021)
Abstract The development of glioblastoma (GBM) is typically accompanied by marked changes in lipid metabolism. Oxylipins and their catalyzed enzymes lipoxygenases (LOXs) have been shown to participate in the development of cancers via multiple pathwa
Externí odkaz:
https://doaj.org/article/ccdca560a3b24a50b54f7ed60998185d
Autor:
Hei‐Man Chow, Jacquelyne Ka‐Li Sun, Ronald P. Hart, Kenneth King‐Yip Cheng, Clara H. L. Hung, Tsun‐Ming Lau, Kin‐Ming Kwan
Publikováno v:
Advanced Science, Vol 8, Iss 16, Pp n/a-n/a (2021)
Abstract Early changes in astrocyte energy metabolism are associated with late‐onset Alzheimer's disease (LOAD), but the underlying mechanism remains elusive. A previous study suggested an association between a synonymous SNP (rs1012672, C→T) in
Externí odkaz:
https://doaj.org/article/20179694e8944d0e88c9468969d8d620
Autor:
Pingjie Wang, Yiyao Liang, Kai Chen, Suk-Yu Yau, Xin Sun, Kenneth King-Yip Cheng, Aimin Xu, Kwok-Fai So, Ang Li
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
Adiponectin, a cytokine secreted by mature adipocytes, proves to be neuroprotective. We have previously reported that running triggers adiponectin up-regulation which subsequently promotes generation of hippocampal neurons and thereby alleviates depr
Externí odkaz:
https://doaj.org/article/c97afd57bd0740ddb60f991c0163a581