Zobrazeno 1 - 10
of 37
pro vyhledávání: '"King Y. Lam"'
Autor:
Annie L.M. Cheung, Xin Yuan Guan, Bin Li, Qing-Yu He, Hui Fang Hu, Nassim Saremi, Alfred King Y. Lam, Yang Wang, W Xu, Sai Wah Tsao, Yan Ru Qin
Publikováno v:
Oncotarget
Metastasis is the most lethal hallmark of esophageal squamous cell carcinoma (ESCC). The aim of the study is to identify key signaling pathways that control metastasis in ESCC. Highly invasive ESCC sublines (designated I3 cells) were established thro
Publikováno v:
Experimental and Molecular Pathology. 102:41-46
Aims The goal of this pilot study was to develop a customized, cost-effective amplicon panel (Ampliseq) for target sequencing in a cohort of patients with sporadic phaeochromocytoma/paraganglioma. Methods Phaeochromocytoma/paragangliomas from 25 pati
Autor:
Liang Han, Di Cui, Stephanie Ma, Yun Zhu, Annie L.M. Cheung, Kwok Wah Chan, Simon Law, Nikki P. Lee, Wen Wen Xu, Bin Li, Alfred King Y. Lam, Xin Yuan Guan, Kin Tak Chan, Sai Wah Tsao, Yan Ru Qin
Publikováno v:
Cancer Science
5‐Fluorouracil (5‐FU) is a chemotherapeutic agent commonly used to treat esophageal squamous cell carcinoma (ESCC), but acquisition of chemoresistance frequently occurs and the underlying mechanisms are not fully understood. We found that microRN
Publikováno v:
Human Pathology. 44:2089-2096
This study investigated the clinicopathologic roles of mammalian target of rapamycin (mTOR) expression and its relationship to carcinogenesis and tumor progression in a colorectal adenoma-adenocarcinoma model. Two colon cancer cell lines with differe
Autor:
R. W.L. Cheung, John Wong, Sai Wah Tsao, C. H. Chui, Yun Wen Chen, F. B.F. Law, Simon Law, Kai-Yau Wong, Qian Tao, Johnny Cheuk On Tang, King Y. Lam, Ping Yin Lee, Gopesh Srivastava, J. Ying, Cordelia Langford
Publikováno v:
Oncogene. 26:5877-5888
By comparative DNA fingerprinting, we identified a 357-bp DNA fragment frequently amplified in esophageal squamous cell carcinomas (ESCC). This fragment overlaps with an expressed sequence tag mapped to 7q22. Further 5' and 3'-rapid amplification of
Publikováno v:
Journal of Oral Pathology & Medicine. 27:407-410
We report a case of pleomorphic adenoma with extensive squamous metaplasia in the palate of a 52-year-old Chinese man. The dimensions of the tumor were 15 x 13 x 13 mm. More than 95% of the epithelial element in the tumor was composed of sheets of sq
Autor:
King Y. Lam, Simon Law, John Wong, Gopesh Srivastava, Thomas S.K. Wan, Yok-Lam Kwong, Edmond S. K. Ma, LC Chan, Ying Chuan Hu
Publikováno v:
Cancer Genetics and Cytogenetics. 135:120-127
The establishment of esophageal cancer cell lines can facilitate the search for molecular mechanisms underlying its pathogenesis. Two novel human esophageal squamous cell carcinoma (ESCC) cell lines, HKESC-2 and HKESC-3, were established from a moder
Publikováno v:
Pathology. 49:S86
Publikováno v:
Journal of Oral Pathology & Medicine. 29:167-172
The aim of the present study is to study the relationship between cyclin D1 and the clinicopathological features of oral squamous cell carcinomas. The cyclin D1 and p53 expression in oral squamous cell carcinomas from 56 patients (45 men, 11 women) w
Autor:
Victor Wai-Lun Tang, King Y. Lam
Publikováno v:
Archives of Pathology & Laboratory Medicine. 124:526-530
Objective.—The clinicopathologic features of splenic metastases have seldom been investigated. The aim of this study was to evaluate the clinical and pathological impact of splenic metastases. Case Material.—We reviewed the clinical/autopsy recor