Zobrazeno 1 - 9
of 9
pro vyhledávání: '"King Onf."'
Autor:
Anthony Tumber, N.A. Burgess-Brown, Michael A. McDonough, Clarisse Lejeune, F. von Delft, Kar Kheng Yeoh, Paul Brennan, Brian D. Marsden, Xuan Shirley Li, T. Krojer, Mun Chiang Chan, S.S. Ng, Carina Gileadi, Grazyna Kochan, Anna M. Rydzik, Akane Kawamura, Robert J. Klose, M. Daniel, Claire Strain-Damerell, Louise J. Walport, Leung Ikh., K.H. Che, Udo Oppermann, Rasheduzzaman Chowdhury, Nathan R. Rose, Woon Ecy., Susanne Müller, Christopher J. Schofield, Richard J. Hopkinson, King Onf., James E. Dunford, Peter J. Ratcliffe
Publikováno v:
Journal of Medicinal Chemistry
The JmjC oxygenases catalyze the N-demethylation of N(ε)-methyl lysine residues in histones and are current therapeutic targets. A set of human 2-oxoglutarate analogues were screened using a unified assay platform for JmjC demethylases and related o
Autor:
King ONF; Diamond Light Source, Harwell Science and Innovation Campus, Didcot OX11 0DE, United Kingdom., Levik KE; Diamond Light Source, Harwell Science and Innovation Campus, Didcot OX11 0DE, United Kingdom., Sandy J; Diamond Light Source, Harwell Science and Innovation Campus, Didcot OX11 0DE, United Kingdom., Basham M; Diamond Light Source, Harwell Science and Innovation Campus, Didcot OX11 0DE, United Kingdom.
Publikováno v:
Acta crystallographica. Section D, Structural biology [Acta Crystallogr D Struct Biol] 2024 Oct 01; Vol. 80 (Pt 10), pp. 744-764. Date of Electronic Publication: 2024 Oct 01.
Autor:
Smith P; The Rosalind Franklin Institute, Harwell Campus, Fermi Avenue, Didcot, OX11 0FA, UK., King ONF; Diamond Light Source, Harwell Campus, Fermi Avenue, Didcot, OX11 0DE, UK., Pennington A; The Rosalind Franklin Institute, Harwell Campus, Fermi Avenue, Didcot, OX11 0FA, UK.; Diamond Light Source, Harwell Campus, Fermi Avenue, Didcot, OX11 0DE, UK., Tun W; Diamond Light Source, Harwell Campus, Fermi Avenue, Didcot, OX11 0DE, UK., Basham M; The Rosalind Franklin Institute, Harwell Campus, Fermi Avenue, Didcot, OX11 0FA, UK.; Diamond Light Source, Harwell Campus, Fermi Avenue, Didcot, OX11 0DE, UK., Jones ML; The Francis Crick Institute, London, NW1 1AT, UK., Collinson LM; The Francis Crick Institute, London, NW1 1AT, UK., Darrow MC; The Rosalind Franklin Institute, Harwell Campus, Fermi Avenue, Didcot, OX11 0FA, UK. michele.darrow@rfi.ac.uk., Spiers H; The Francis Crick Institute, London, NW1 1AT, UK. bowerssh@crick.ac.uk.
Publikováno v:
Histochemistry and cell biology [Histochem Cell Biol] 2023 Sep; Vol. 160 (3), pp. 253-276. Date of Electronic Publication: 2023 Jun 07.
Autor:
Pennington A; Diamond Light Source Ltd., Didcot, United Kingdom., King ONF; Diamond Light Source Ltd., Didcot, United Kingdom., Tun WM; Diamond Light Source Ltd., Didcot, United Kingdom., Ho EML; The Rosalind Franklin Institute, Didcot, United Kingdom., Luengo I; Diamond Light Source Ltd., Didcot, United Kingdom., Darrow MC; The Rosalind Franklin Institute, Didcot, United Kingdom., Basham M; Diamond Light Source Ltd., Didcot, United Kingdom.; The Rosalind Franklin Institute, Didcot, United Kingdom.
Publikováno v:
Frontiers in cell and developmental biology [Front Cell Dev Biol] 2022 Apr 01; Vol. 10, pp. 842342. Date of Electronic Publication: 2022 Apr 01 (Print Publication: 2022).
Autor:
Reinhard C; Diamond Light Source, Harwell Science and Innovation Campus, Didcot, Oxfordshire OX11 0DE, United Kingdom., Drakopoulos M; NSLS-II, Brookhaven National Laboratory, Upton, NY 11973, USA., Ahmed SI; Diamond Light Source, Harwell Science and Innovation Campus, Didcot, Oxfordshire OX11 0DE, United Kingdom., Deyhle H; Diamond Light Source, Harwell Science and Innovation Campus, Didcot, Oxfordshire OX11 0DE, United Kingdom., James A; Diamond Light Source, Harwell Science and Innovation Campus, Didcot, Oxfordshire OX11 0DE, United Kingdom., Charlesworth CM; Diamond Light Source, Harwell Science and Innovation Campus, Didcot, Oxfordshire OX11 0DE, United Kingdom., Burt M; Diamond Light Source, Harwell Science and Innovation Campus, Didcot, Oxfordshire OX11 0DE, United Kingdom., Sutter J; Diamond Light Source, Harwell Science and Innovation Campus, Didcot, Oxfordshire OX11 0DE, United Kingdom., Alexander S; Diamond Light Source, Harwell Science and Innovation Campus, Didcot, Oxfordshire OX11 0DE, United Kingdom., Garland P; Diamond Light Source, Harwell Science and Innovation Campus, Didcot, Oxfordshire OX11 0DE, United Kingdom., Yates T; Diamond Light Source, Harwell Science and Innovation Campus, Didcot, Oxfordshire OX11 0DE, United Kingdom., Marshall R; Diamond Light Source, Harwell Science and Innovation Campus, Didcot, Oxfordshire OX11 0DE, United Kingdom., Kemp B; Diamond Light Source, Harwell Science and Innovation Campus, Didcot, Oxfordshire OX11 0DE, United Kingdom., Warrick E; Diamond Light Source, Harwell Science and Innovation Campus, Didcot, Oxfordshire OX11 0DE, United Kingdom., Pueyos A; Diamond Light Source, Harwell Science and Innovation Campus, Didcot, Oxfordshire OX11 0DE, United Kingdom., Bradnick B; Diamond Light Source, Harwell Science and Innovation Campus, Didcot, Oxfordshire OX11 0DE, United Kingdom., Nagni M; Diamond Light Source, Harwell Science and Innovation Campus, Didcot, Oxfordshire OX11 0DE, United Kingdom., Winter AD; Diamond Light Source, Harwell Science and Innovation Campus, Didcot, Oxfordshire OX11 0DE, United Kingdom., Filik J; Diamond Light Source, Harwell Science and Innovation Campus, Didcot, Oxfordshire OX11 0DE, United Kingdom., Basham M; Rosalind Franklin Institute, Harwell Science and Innovation Campus, Didcot, Oxfordshire OX11 0FA, United Kingdom., Wadeson N; Diamond Light Source, Harwell Science and Innovation Campus, Didcot, Oxfordshire OX11 0DE, United Kingdom., King ONF; Diamond Light Source, Harwell Science and Innovation Campus, Didcot, Oxfordshire OX11 0DE, United Kingdom., Aslani N; Diamond Light Source, Harwell Science and Innovation Campus, Didcot, Oxfordshire OX11 0DE, United Kingdom., Dent AJ; Diamond Light Source, Harwell Science and Innovation Campus, Didcot, Oxfordshire OX11 0DE, United Kingdom.
Publikováno v:
Journal of synchrotron radiation [J Synchrotron Radiat] 2021 Nov 01; Vol. 28 (Pt 6), pp. 1985-1995. Date of Electronic Publication: 2021 Oct 22.
Autor:
Tun WM; Diamond Light Source, Didcot OX11 0DE, UK., Poologasundarampillai G; School of Dentistry, University of Birmingham, Birmingham B15 2TT, UK., Bischof H; Maternal and Fetal Health Research Centre, School of Medical Sciences, University of Manchester, Manchester, UK.; MAHSC, St Mary's Hospital, NHS MFT, Manchester M13 9WL, UK., Nye G; Chester Medical School, University of Chester, Chester CH1 4BJ, UK., King ONF; Diamond Light Source, Didcot OX11 0DE, UK., Basham M; Diamond Light Source, Didcot OX11 0DE, UK.; Rosalind Franklin Institute, Didcot OX11 0DE, UK., Tokudome Y; Department of Materials Science, Graduate School of Engineering, Osaka Prefecture University, Osaka 599-8531, Japan., Lewis RM; Faculty of Medicine, University of Southampton, Southampton SO16 6YD, UK., Johnstone ED; Maternal and Fetal Health Research Centre, School of Medical Sciences, University of Manchester, Manchester, UK.; MAHSC, St Mary's Hospital, NHS MFT, Manchester M13 9WL, UK., Brownbill P; Maternal and Fetal Health Research Centre, School of Medical Sciences, University of Manchester, Manchester, UK.; MAHSC, St Mary's Hospital, NHS MFT, Manchester M13 9WL, UK., Darrow M; SPT Labtech Ltd, Melbourn SG8 6HB, UK., Chernyavsky IL; Maternal and Fetal Health Research Centre, School of Medical Sciences, University of Manchester, Manchester, UK.; MAHSC, St Mary's Hospital, NHS MFT, Manchester M13 9WL, UK.; Department of Mathematics, University of Manchester, Manchester M13 9PL, UK.
Publikováno v:
Journal of the Royal Society, Interface [J R Soc Interface] 2021 Jun; Vol. 18 (179), pp. 20210140. Date of Electronic Publication: 2021 Jun 02.
Autor:
McAllister TE; Department of Chemistry , University of Oxford , Chemistry Research Laboratory , 12 Mansfield Road , Oxford OX1 3TA , UK . Email: akane.kawamura@chem.ox.ac.uk., Yeh TL; Department of Chemistry , University of Oxford , Chemistry Research Laboratory , 12 Mansfield Road , Oxford OX1 3TA , UK . Email: akane.kawamura@chem.ox.ac.uk., Abboud MI; Department of Chemistry , University of Oxford , Chemistry Research Laboratory , 12 Mansfield Road , Oxford OX1 3TA , UK . Email: akane.kawamura@chem.ox.ac.uk., Leung IKH; Department of Chemistry , University of Oxford , Chemistry Research Laboratory , 12 Mansfield Road , Oxford OX1 3TA , UK . Email: akane.kawamura@chem.ox.ac.uk.; School of Chemical Sciences , The University of Auckland , Private Bag 92019 , Auckland 1142 , New Zealand., Hookway ES; Botnar Research Centre , NIHR Oxford Biomedical Research Unit , University of Oxford , Windmill Road , Oxford , OX3 7LD , UK., King ONF; Department of Chemistry , University of Oxford , Chemistry Research Laboratory , 12 Mansfield Road , Oxford OX1 3TA , UK . Email: akane.kawamura@chem.ox.ac.uk., Bhushan B; Department of Chemistry , University of Oxford , Chemistry Research Laboratory , 12 Mansfield Road , Oxford OX1 3TA , UK . Email: akane.kawamura@chem.ox.ac.uk.; Division of Cardiovascular Medicine , Radcliffe Department of Medicine , University of Oxford , Wellcome Trust Centre for Human Genetics , Roosevelt Drive , Oxford OX3 7BN , UK., Williams ST; Department of Chemistry , University of Oxford , Chemistry Research Laboratory , 12 Mansfield Road , Oxford OX1 3TA , UK . Email: akane.kawamura@chem.ox.ac.uk., Hopkinson RJ; Department of Chemistry , University of Oxford , Chemistry Research Laboratory , 12 Mansfield Road , Oxford OX1 3TA , UK . Email: akane.kawamura@chem.ox.ac.uk., Münzel M; Department of Chemistry , University of Oxford , Chemistry Research Laboratory , 12 Mansfield Road , Oxford OX1 3TA , UK . Email: akane.kawamura@chem.ox.ac.uk., Loik ND; Department of Chemistry , Graduate School of Science , The University of Tokyo , Tokyo 113-0033 , Japan., Chowdhury R; Department of Chemistry , University of Oxford , Chemistry Research Laboratory , 12 Mansfield Road , Oxford OX1 3TA , UK . Email: akane.kawamura@chem.ox.ac.uk., Oppermann U; Botnar Research Centre , NIHR Oxford Biomedical Research Unit , University of Oxford , Windmill Road , Oxford , OX3 7LD , UK., Claridge TDW; Department of Chemistry , University of Oxford , Chemistry Research Laboratory , 12 Mansfield Road , Oxford OX1 3TA , UK . Email: akane.kawamura@chem.ox.ac.uk., Goto Y; Department of Chemistry , Graduate School of Science , The University of Tokyo , Tokyo 113-0033 , Japan., Suga H; Department of Chemistry , Graduate School of Science , The University of Tokyo , Tokyo 113-0033 , Japan.; JST , CREST , The University of Tokyo , Tokyo 113-0033 , Japan., Schofield CJ; Department of Chemistry , University of Oxford , Chemistry Research Laboratory , 12 Mansfield Road , Oxford OX1 3TA , UK . Email: akane.kawamura@chem.ox.ac.uk., Kawamura A; Department of Chemistry , University of Oxford , Chemistry Research Laboratory , 12 Mansfield Road , Oxford OX1 3TA , UK . Email: akane.kawamura@chem.ox.ac.uk.; Division of Cardiovascular Medicine , Radcliffe Department of Medicine , University of Oxford , Wellcome Trust Centre for Human Genetics , Roosevelt Drive , Oxford OX3 7BN , UK.
Publikováno v:
Chemical science [Chem Sci] 2018 Apr 23; Vol. 9 (20), pp. 4569-4578. Date of Electronic Publication: 2018 Apr 23 (Print Publication: 2018).
Autor:
Hopkinson RJ; Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Mansfield Road, Oxford, OX1 3TA, U.K., Tumber A; Structural Genomics Consortium, University of Oxford, Headington, OX3 7DQ, U.K.; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, OX3 7FZ, UK., Yapp C; Structural Genomics Consortium, University of Oxford, Headington, OX3 7DQ, U.K., Chowdhury R; Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Mansfield Road, Oxford, OX1 3TA, U.K., Aik W; Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Mansfield Road, Oxford, OX1 3TA, U.K., Che KH; Structural Genomics Consortium, University of Oxford, Headington, OX3 7DQ, U.K.; Botnar Research Centre, Oxford Biomedical Research Unit, Oxford OX3 7LD, U.K., Li XS; Epigenetic Regulation of Chromatin Function Group, Department of Biochemistry, University of Oxford, South Parks Road, Oxford, OX1 3QU, U.K., Kristensen JBL; Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Mansfield Road, Oxford, OX1 3TA, U.K.; Department of Medicinal Chemistry, Faculty of Pharmaceutical Sciences, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen, Denmark., King ONF; Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Mansfield Road, Oxford, OX1 3TA, U.K., Chan MC; Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Mansfield Road, Oxford, OX1 3TA, U.K.; Henry Wellcome Building for Molecular Physiology, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford OX3 7LD, U.K., Yeoh KK; Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Mansfield Road, Oxford, OX1 3TA, U.K.; Henry Wellcome Building for Molecular Physiology, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford OX3 7LD, U.K., Choi H; Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Mansfield Road, Oxford, OX1 3TA, U.K., Walport LJ; Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Mansfield Road, Oxford, OX1 3TA, U.K., Thinnes CC; Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Mansfield Road, Oxford, OX1 3TA, U.K., Bush JT; Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Mansfield Road, Oxford, OX1 3TA, U.K., Lejeune C; Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Mansfield Road, Oxford, OX1 3TA, U.K., Rydzik AM; Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Mansfield Road, Oxford, OX1 3TA, U.K., Rose NR; Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Mansfield Road, Oxford, OX1 3TA, U.K.; Epigenetic Regulation of Chromatin Function Group, Department of Biochemistry, University of Oxford, South Parks Road, Oxford, OX1 3QU, U.K., Bagg EA; Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Mansfield Road, Oxford, OX1 3TA, U.K., McDonough MA; Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Mansfield Road, Oxford, OX1 3TA, U.K., Krojer T; Structural Genomics Consortium, University of Oxford, Headington, OX3 7DQ, U.K., Yue WW; Structural Genomics Consortium, University of Oxford, Headington, OX3 7DQ, U.K., Ng SS; Structural Genomics Consortium, University of Oxford, Headington, OX3 7DQ, U.K., Olsen L; Department of Medicinal Chemistry, Faculty of Pharmaceutical Sciences, University of Copenhagen, Universitetsparken 2, DK-2100 Copenhagen, Denmark., Brennan PE; Structural Genomics Consortium, University of Oxford, Headington, OX3 7DQ, U.K.; Target Discovery Institute, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, OX3 7FZ, UK., Oppermann U; Structural Genomics Consortium, University of Oxford, Headington, OX3 7DQ, U.K.; Botnar Research Centre, Oxford Biomedical Research Unit, Oxford OX3 7LD, U.K., Muller-Knapp S; Structural Genomics Consortium, University of Oxford, Headington, OX3 7DQ, U.K., Klose RJ; Epigenetic Regulation of Chromatin Function Group, Department of Biochemistry, University of Oxford, South Parks Road, Oxford, OX1 3QU, U.K., Ratcliffe PJ; Henry Wellcome Building for Molecular Physiology, Nuffield Department of Medicine, University of Oxford, Roosevelt Drive, Oxford OX3 7LD, U.K., Schofield CJ; Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Mansfield Road, Oxford, OX1 3TA, U.K., Kawamura A; Chemistry Research Laboratory, Department of Chemistry, University of Oxford, Mansfield Road, Oxford, OX1 3TA, U.K.; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, Wellcome Trust Centre for Human Genetics, Roosevelt Drive, Oxford, OX3 7LD, UK.
Publikováno v:
Chemical science [Chem Sci] 2013 Aug 01; Vol. 4 (8), pp. 3110-3117.
Autor:
Chang KH; Chemistry Research Laboratory, University of Oxford Oxford, OX1 3TA, United Kingdom., King ONF; Chemistry Research Laboratory, University of Oxford Oxford, OX1 3TA, United Kingdom., Tumber A; Structural Genomics Consortium, University of Oxford, Old Road Campus Research Building, Oxford, OX3 7DQ, United Kingdom., Woon ECY; Chemistry Research Laboratory, University of Oxford Oxford, OX1 3TA, United Kingdom., Heightman TD; Structural Genomics Consortium, University of Oxford, Old Road Campus Research Building, Oxford, OX3 7DQ, United Kingdom., McDonough MA; Chemistry Research Laboratory, University of Oxford Oxford, OX1 3TA, United Kingdom., Schofield CJ; Chemistry Research Laboratory, University of Oxford Oxford, OX1 3TA, United Kingdom., Rose NR; Chemistry Research Laboratory, University of Oxford Oxford, OX1 3TA, United Kingdom.
Publikováno v:
ChemMedChem [ChemMedChem] 2011 May 02; Vol. 6 (5), pp. 759-764. Date of Electronic Publication: 2011 Mar 15.