Zobrazeno 1 - 10
of 16
pro vyhledávání: '"King Lam Hui"'
Publikováno v:
Cell Reports, Vol 42, Iss 1, Pp 111974- (2023)
Summary: 5-oxoETE is a bioactive lipid derived from arachidonic acid generated when phospholipase A2 activation coincides with oxidative stress. Through its G protein-coupled receptor OXER1, pure 5-oxoETE is a potent leukocyte chemoattractant. Yet, i
Externí odkaz:
https://doaj.org/article/6f11824d337343568297ec2c72713d7b
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c3ad8ca1fa933f9b7caa04afa2d2f1a
https://doi.org/10.2139/ssrn.4119004
https://doi.org/10.2139/ssrn.4119004
Autor:
Zhouyang Shen, Kalina T. Belcheva, Mark Jelcic, King Lam Hui, Anushka Katikaneni, Philipp Niethammer
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance A cell must be able to measure whether the lipid membranes that surround its insides are stretched. Currently, mechanosensitive ion channels are the best-studied class of membrane tension sensors, but recent work suggests that peripheral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5172b78a4c9aed8eb12e1e6ba7924b42
http://europepmc.org/articles/PMC8740744
http://europepmc.org/articles/PMC8740744
Autor:
Zhouyang Shen, Belcheva, Kalina T., Jelcic, Mark, King Lam Hui, Katikaneni, Anushka, Niethammer, Philipp
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 1/4/2022, Vol. 119 Issue 1, p1-9, 9p
Autor:
Mark Jelcic, Xiao-Chuan Cai, Philipp Niethammer, King Lam Hui, Minkui Luo, Balázs Enyedi, Ke Wang
Publikováno v:
Cell Chem Biol
Cell Chemical Biology
Cell Chemical Biology
Summary ATP is an important energy metabolite and allosteric signal in health and disease. ATP-interacting proteins, such as P2 receptors, control inflammation, cell death, migration, and wound healing. However, identification of allosteric ATP sites
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16dd37b3ce0c8b225507886f0a0c275c
https://doi.org/10.1016/j.chembiol.2020.05.010
https://doi.org/10.1016/j.chembiol.2020.05.010
Autor:
King Lam Hui, Arpita Upadhyaya
Publikováno v:
Proceedings of the National Academy of Sciences. 114
T-cell receptor (TCR) triggering and subsequent T-cell activation are essential for the adaptive immune response. Recently, multiple lines of evidence have shown that force transduction across the TCR complex is involved during TCR triggering, and th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8a4cf03f84f1480c95e6a5cc4ad4799
https://doi.org/10.1073/pnas.1614291114
https://doi.org/10.1073/pnas.1614291114
Publikováno v:
Cytoskeleton. 71:119-135
Contact formation of T cells with antigen presenting cells results in the engagement of T cell receptors (TCRs), recruitment and aggregation of signaling proteins into microclusters and ultimately, T cell activation. During this process, T cells unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20bbb814997fa79fce2d58934a19bd76
https://doi.org/10.1002/cm.21156
https://doi.org/10.1002/cm.21156
Publikováno v:
Molecular Biology of the Cell
Cytoskeletal forces are implicated in T-cell–receptor activation, but their determinants are not known. Traction force microscopy was used to measure forces generated during T-cell activation. Whereas actin dynamics were essential for force generat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::defe4a6422468f9ec62d2707df354d08
https://pubmed.ncbi.nlm.nih.gov/25518938
https://pubmed.ncbi.nlm.nih.gov/25518938
Autor:
Silvia Bolland, King Lam Hui, Arpita Upadhyaya, Wenxia Song, Brian Grooman, Heather Miller, Chaohong Liu
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 187(1)
The activation of the BCR, which initiates B cell activation, is triggered by Ag-induced self-aggregation and clustering of receptors at the cell surface. Although Ag-induced actin reorganization is known to be involved in BCR clustering in response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27d66ef66795fee7a5fa0d1125d091a3
https://pubmed.ncbi.nlm.nih.gov/21622861
https://pubmed.ncbi.nlm.nih.gov/21622861
Autor:
Arpita Upadhyaya, King Lam Hui
Publikováno v:
Biophysical Journal. 108:142a
T cell activation is critical for the adaptive immune response in the body. The binding of the T cell receptor (TCR) with antigen on the surface of antigen presenting cells (APC) triggers signaling cascades and cell spreading. Physical forces exerted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79e1e0ff38d39fff1c8af7fc060f7acd
https://doi.org/10.1016/j.bpj.2014.11.785
https://doi.org/10.1016/j.bpj.2014.11.785