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pro vyhledávání: '"Kinesin binding"'
Akademický článek
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Autor:
Joseph Atherton, Jessica JA Hummel, Natacha Olieric, Julia Locke, Alejandro Peña, Steven S Rosenfeld, Michel O Steinmetz, Casper C Hoogenraad, Carolyn A Moores
Publikováno v:
eLife, Vol 9 (2020)
Subcellular compartmentalisation is necessary for eukaryotic cell function. Spatial and temporal regulation of kinesin activity is essential for building these local environments via control of intracellular cargo distribution. Kinesin-binding protei
Externí odkaz:
https://doaj.org/article/afd807016c264f458e22f75004d72461
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 12 (2019)
Kinesin-binding protein (KBP; KIF1BP; KIAA1279) functions as a regulator for a subset of kinesins, many of which play important roles in neural development. Previous studies have shown that KBP is expressed in nearly all tissue with cytoplasmic local
Externí odkaz:
https://doaj.org/article/64cb0425036741f6ab9bcd41c1bb5a58
Autor:
Joseph Atherton, Carolyn A. Moores
Publikováno v:
Acta Crystallographica. Section D, Structural Biology
Sample preparation is a major limiting factor in cryo-electron microscopy (cryo-EM), particularly for small macromolecules under 100 kDa. Here, experiences in preparing kinesin-binding protein (KBP; 72 kDa) and KBP–kinesin motor domain (110 kDa) sa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::212649a5f93f96bc15330f6a1c607b35
https://doi.org/10.1107/s2059798321001935
https://doi.org/10.1107/s2059798321001935
Publikováno v:
Bûlleten' Sibirskoj Mediciny, Vol 19, Iss 1, Pp 108-113 (2020)
We identified significant functions of susceptibility-genes and performed an analysis of pathway enrichment for Alzheimer’s disease, Parkinson’s disease and for both of them. Genes were extracted from a Catalog of Published Genome-Wide Associatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50e209861d0e4f39540f97e610f205b9
https://doi.org/10.20538/1682-0363-2020-1-108-113
https://doi.org/10.20538/1682-0363-2020-1-108-113
Autor:
Ryoma Ohi, David Sept, Jason Stumpff, Zhenyu Tan, Michael A. Cianfrocco, April L. Solon, Katherine L. Schutt, Alexey I. Nesvizhskii, Lauren Jepsen, Sarah E. Haynes
Kinesins are tightly regulated in space and time to control their activation in the absence of cargo-binding. Kinesin-binding protein (KIFBP) was recently discovered to bind the catalytic motor heads of 8 of the 45 known kinesin superfamily members a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b44d0d56d7346bd89a4bba595aec0b3c
https://doi.org/10.1101/2021.06.02.446814
https://doi.org/10.1101/2021.06.02.446814
Autor:
Jason Stumpff, Lauren Jepsen, Katherine L. Schutt, April L. Solon, Sarah E. Haynes, David Sept, Michael A. Cianfrocco, Alexey I. Nesvizhskii, Ryoma Ohi, Zhenyu Tan
Publikováno v:
Science Advances
Description
Kinesin-binding protein inhibits kinesin activity through structural alterations of the kinesin motor domain.
Kinesins are regulated in space and time to ensure activation only in the presence of cargo. Kinesin-binding protein (
Kinesin-binding protein inhibits kinesin activity through structural alterations of the kinesin motor domain.
Kinesins are regulated in space and time to ensure activation only in the presence of cargo. Kinesin-binding protein (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77be392396066c958044d0adeb1b7385
http://europepmc.org/articles/PMC8604404
http://europepmc.org/articles/PMC8604404
Many members in the kinesin superfamily walk predominantly towards the plus end of the micro-tubule (MT) in a hand-over-hand manner. Despite great progress in elucidating the mechanism of stepping kinetics, the origin of stepping directionality is no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5257b3759c894ac691c29cea98067bae
https://doi.org/10.1101/2021.08.30.458176
https://doi.org/10.1101/2021.08.30.458176
Autor:
Carolyn A. Moores, Jessica J.A. Hummel, Joseph Atherton, Casper C. Hoogenraad, Natacha Olieric, Michel O. Steinmetz, Steven S. Rosenfeld, Alejandro Peña, Julia Locke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aed1202430ff67a01f8333afb4cfc57a
https://doi.org/10.7554/elife.61481.sa2
https://doi.org/10.7554/elife.61481.sa2
Autor:
Michel O. Steinmetz, Alejandro Peña, Joseph Atherton, Casper C. Hoogenraad, Carolyn A. Moores, Jessica J.A. Hummel, Natacha Olieric, Steven S. Rosenfeld, Julia Locke
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
Subcellular compartmentalisation is necessary for eukaryotic cell function. Spatial and temporal regulation of kinesin activity is essential for building these local environments via control of intracellular cargo distribution. Kinesin-binding protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e70e40040f830f1596c9ce4bf8b96e56
http://europepmc.org/articles/PMC7746232
http://europepmc.org/articles/PMC7746232