MAP7D2 Localizes to the Proximal Axon and Locally Promotes Kinesin-1-Mediated Cargo Transport into the Axon

Autor: Pan, Xingxiu, Cao, Yujie, Stucchi, Riccardo, Hooikaas, Peter Jan, Portegies, Sybren, Will, Lena, Martin, Maud, Akhmanova, Anna, Harterink, Martin, Hoogenraad, Casper C, Sub Cell Biology, Celbiologie

Publikováno v: Cell Reports
Cell reports, 26 (8
Cell Reports, 26(8), 1988. Elsevier Saunders
Cell Reports, Vol 26, Iss 8, Pp 1988-1999.e6 (2019)

Summary The motor protein kinesin-1 plays an important role in polarized sorting of transport vesicles to the axon. However, the mechanism by which the axonal entry of kinesin-1-dependent cargo transport is regulated remains unclear. Microtubule-asso

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62797fd73903cd6e72db1b2fb88cf9db
https://pubmed.ncbi.nlm.nih.gov/30784582

Coupling fission and exit of RAB6 vesicles at Golgi hotspots through kinesin-myosin interactions

Autor: Ariane Dimitrov, Raja Bonifay, Cécile Bougeret, Hugo Bousquet, Gaëlle Bressanelli, Arnaud Echard, Vincent Fraisier, Bruno Goud, Olena Pylypenko, Sabine Bardin, Catherine Guillou, Anne Houdusse, Stéphanie Miserey-Lenkei

Publikováno v: Nature Communications
Nature Communications, 2017, 8 (1), pp.1254. ⟨10.1038/s41467-017-01266-0⟩
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Nature Communications, Nature Publishing Group, 2017, 8 (1), pp.1254. ⟨10.1038/s41467-017-01266-0⟩
'Nature Communications ', vol: 8, pages: 1254-1-1254-13 (2017)

The actin and microtubule cytoskeletons play important roles in Golgi structure and function, but how they are connected remain poorly known. In this study, we investigated whether RAB6 GTPase, a Golgi-associated RAB involved in the regulation of sev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94563cceacba255a8dcff764307474b1
https://doi.org/10.1038/s41467-017-01266-0

Genome-wide RNAi screen for synthetic lethal interactions with the C. elegans kinesin-5 homolog BMK-1

Autor: Maia, André F, Tanenbaum, Marvin E, Galli, Matilde, Lelieveld, Daphne, Egan, David A, Gassmann, Reto, Sunkel, Claudio E, van den Heuvel, Sander, Medema, René H, Sub Developmental Biology, Dep Biologie, Developmental Biology

Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Scientific Data
Scientific data, 2. Nature Publishing Group

Kinesins are a superfamily of microtubule-based molecular motors that perform various transport needs and have essential roles in cell division. Among these, the kinesin-5 family has been shown to play a major role in the formation and maintenance of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54fb58e265ec7cbc5b2558ba27cc077e
https://dspace.library.uu.nl/handle/1874/333256

CYK-4: A Rho family gtpase activating protein (GAP) required for central spindle formation and cytokinesis

Autor: Jantsch-Plunger, V., Gönczy, P., Romano, A., Schnabel, H., Hamill, D., Schnabel, R., Hyman, A. A., Glotzer, M.

Publikováno v: The Journal of Cell Biology
Journal of Cell Biology, vol. 149, no. 7, pp. 1391-1404

During cytokinesis of animal cells, the mitotic spindle plays at least two roles. Initially, the spindle positions the contractile ring. Subsequently, the central spindle, which is composed of microtubule bundles that form during anaphase, promotes a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ff0ffa78a4d7cad40cd75f025ae47f5f
https://pubmed.ncbi.nlm.nih.gov/10871280