Oxidative stress and Na,K-ATPase activity differential regulation in brainstem and forebrain of Wistar Audiogenic rats may lead to increased seizure susceptibility

Autor: Norberto Garcia-Cairasco, Gabriela Machado Parreira, Cristiane Queixa Tilelli, Lívea Dornela Godoy, Eduardo H.L. Umeoka, Israel José Pereira Garcia, Leandro A. Barbosa, Hérica de Lima Santos, Maria Daniela Aparecida Resende, Daniela Bueno Sartori

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Parreira, G M, Resende, M D A, Garcia, I J P, Sartori, D B, Umeoka, E H D L, Godoy, L D, Garcia-Cairasco, N, Barbosa, L A, Santos, H D L & Tilelli, C Q 2018, ' Oxidative stress and Na,K-ATPase activity differential regulation in brainstem and forebrain of Wistar Audiogenic rats may lead to increased seizure susceptibility ', Brain Research, vol. 1679, pp. 171-178 . https://doi.org/10.1016/j.brainres.2017.12.001

The Wistar Audiogenic Rat (WAR) is a well-characterized seizure-prone, inbred rodent strain that, when acutely stimulated with high-intensity sounds, develops brainstem-dependent tonic-clonic seizures that can evolve to limbic-like, myoclonic (forebr

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