Substrate Specificity and Novel Selective Inhibitors of TNF-α Converting Enzyme (TACE) from Two-Dimensional Substrate Mapping

Autor: Lambert, Millard H., Blackburn, R. Kevin, Seaton, Theresa D., Kassel, Daniel B., Kinder, Daniel S., Leesnitzer, M. Anthony, Bickett, D. Mark, Warner, Janet R., Andersen, Marc W., Badiang, Jennifer G., Cowan, David J., Gaul, Michael D, Petrov, Kimberly G., Rabinowitz, Michael H., Wiethe, Robert W., Becherer, J. David, McDougald, Darryl L., Musso, David L., Andrews, Robert C., Moss, Marcia L.

Publikováno v: Combinatorial Chemistry & High Throughput Screening; June 2005, Vol. 8 Issue: 4 p327-339, 13p

Substrate specificity and novel selective inhibitors of TNF-alpha converting enzyme (TACE) from two-dimensional substrate mapping.

Autor: Lambert MH; Department of Computational Chemistry, GlaxoSmithKline Research and Development, 5 Moore Drive, RTP, NC 27709, USA. mill.h.lambert@gsk.com, Blackburn RK, Seaton TD, Kassel DB, Kinder DS, Leesnitzer MA, Bickett DM, Warner JR, Andersen MW, Badiang JG, Cowan DJ, Gaul MD, Petrov KG, Rabinowitz MH, Wiethe RW, Becherer JD, McDougald DL, Musso DL, Andrews RC, Moss ML

Publikováno v: Combinatorial chemistry & high throughput screening [Comb Chem High Throughput Screen] 2005 Jun; Vol. 8 (4), pp. 327-39.