Zobrazeno 1 - 10
of 574
pro vyhledávání: '"Kinchesh, P."'
Autor:
Veerle Kersemans, Stuart Gilchrist, Philip Danny Allen, Sheena Wallington, Paul Kinchesh, John Prentice, Martin Tweedie, Jamie H. Warner, Sean C. Smart
Publikováno v:
Tomography, Vol 7, Iss 1, Pp 39-54 (2021)
Standardisation of animal handling procedures for a wide range of preclinical imaging scanners will improve imaging performance and reproducibility of scientific data. Whilst there has been significant effort in defining how well scanners should oper
Externí odkaz:
https://doaj.org/article/3fc158c941f949b28b6b95cbb43029c6
Autor:
Emma Jones, Andrew Godkin, Sarah Nicol Lauder, Kathryn Smart, Veerle Kersemans, Danny Allen, Jake Scott, Ana Pires, Stefan Milutinovic, Michelle Somerville, Sean Smart, Paul Kinchesh, Elena Lopez-Guadamillas, Ellyn Hughes, Martin Scurr, Lori S Friedman, Bart Vanhaesebroeck, Awen Gallimore
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Despite striking successes, immunotherapies aimed at increasing cancer-specific T cell responses are unsuccessful in most patients with cancer. Inactivating regulatory T cells (Treg) by inhibiting the PI3Kδ signaling enzyme has shown prom
Externí odkaz:
https://doaj.org/article/03253b8693d64d3c84a6f9eeb342088e
Publikováno v:
Healthcare Technology Letters (2019)
Oxygen loaded microbubbles are being investigated as a means of reducing tumour hypoxia in order to improve response to cancer therapy. To optimise this approach, it is desirable to be able to measure changes in tissue oxygenation in real-time during
Externí odkaz:
https://doaj.org/article/2e459a6e75a04efab030793626662d55
Autor:
Ana L Gomes, Paul Kinchesh, Stuart Gilchrist, Philip D Allen, Luiza Madia Lourenço, Anderson J Ryan, Sean C Smart
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0212172 (2019)
The identification and measurement of tumours is a key requirement in the study of tumour development in mouse models of human cancer. Disease burden in autochthonous tumours, such as those arising in the lung, can be seen with non-invasive imaging,
Externí odkaz:
https://doaj.org/article/0cdd933fe5b64c7eafda8fdc20e58782
Objective Oxygen-loaded nanobubbles have shown potential for reducing tumour hypoxia and improving treatment outcomes, however, it remains difficult to noninvasively measure the changes in partial pressure of oxygen (PO2) in vivo. The linear relation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c60e63c55b45a25f871dffec154beb01
https://ora.ox.ac.uk/objects/uuid:af5f0743-5d62-4ba1-b2d0-5d97a7aa6496
https://ora.ox.ac.uk/objects/uuid:af5f0743-5d62-4ba1-b2d0-5d97a7aa6496
Autor:
Veerle Kersemans, John S Beech, Stuart Gilchrist, Paul Kinchesh, Philip D Allen, James Thompson, Ana L Gomes, Zenobia D'Costa, Luke Bird, Iain D C Tullis, Robert G Newman, Aurelien Corroyer-Dulmont, Nadia Falzone, Abul Azad, Katherine A Vallis, Owen J Sansom, Ruth J Muschel, Borivoj Vojnovic, Mark A Hill, Emmanouil Fokas, Sean C Smart
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0176693 (2017)
Preclinical CT-guided radiotherapy platforms are increasingly used but the CT images are characterized by poor soft tissue contrast. The aim of this study was to develop a robust and accurate method of MRI-guided radiotherapy (MR-IGRT) delivery to ab
Externí odkaz:
https://doaj.org/article/ae518cca3a5a4ee6a6bf6b30edf910b8
Akademický článek
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Akademický článek
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Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0164920 (2016)
To develop an MRI-compatible resistive heater, using high frequency alternating current (AC), for temperature maintenance of anaesthetised animals.An MRI-compatible resistive electrical heater was formed from narrow gauge wire connected to a high fre
Externí odkaz:
https://doaj.org/article/3aa91842a5ff4cd783a6041d110222cd
Autor:
Veerle Kersemans, Pavitra Kannan, John S Beech, Russell Bates, Benjamin Irving, Stuart Gilchrist, Philip D Allen, James Thompson, Paul Kinchesh, Christophe Casteleyn, Julia Schnabel, Mike Partridge, Ruth J Muschel, Sean C Smart
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0128537 (2015)
Preclinical in vivo CT is commonly used to visualise vessels at a macroscopic scale. However, it is prone to many artefacts which can degrade the quality of CT images significantly. Although some artefacts can be partially corrected for during image
Externí odkaz:
https://doaj.org/article/ed6f36bc39f44202a4c525d14f8c532a