Zobrazeno 1 - 10
of 699
pro vyhledávání: '"Kinase Family"'
Autor:
Robin H. G. A. van den Biggelaar, Kimberley V. Walburg, Susan J. F. van den Eeden, Cassandra L. R. van Doorn, Eugenia Meiler, Alex S. de Ries, Annemarie H. Meijer, Tom H. M. Ottenhoff, Anno Saris
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
The increasing prevalence of antimicrobial-resistant Staphylococcus aureus strains, especially methicillin-resistant S. aureus (MRSA), poses a threat to successful antibiotic treatment. Unsuccessful attempts to develop a vaccine and rising resistance
Externí odkaz:
https://doaj.org/article/d4a0576083104c598b9a431663c54c44
Autor:
Fernanda L. Basei, Ivan Rosa e Silva, Pedro R. Firmino Dias, Camila C. Ferezin, Andressa Peres de Oliveira, Luidy K. Issayama, Livia A. R. Moura, Fernando Riback da Silva, Jörg Kobarg
Publikováno v:
Cells, Vol 13, Iss 6, p 473 (2024)
Mitochondria provide energy for all cellular processes, including reactions associated with cell cycle progression, DNA damage repair, and cilia formation. Moreover, mitochondria participate in cell fate decisions between death and survival. Nek fami
Externí odkaz:
https://doaj.org/article/f9ff3481ef8b4b78a60aae8d2123e7c1
Akademický článek
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Autor:
Xiang-Yu Lin, Yu-Wei Huang, You-Wei Fan, Yun-Ti Chen, Nikhil Pathak, Yen-Chao Hsu, Jinn-Moon Yang
Publikováno v:
BMC Bioinformatics, Vol 23, Iss S4, Pp 1-13 (2022)
Abstract Background Human protein kinases, the key players in phosphoryl signal transduction, have been actively investigated as drug targets for complex diseases such as cancer, immune disorders, and Alzheimer’s disease, with more than 60 successf
Externí odkaz:
https://doaj.org/article/df07a3ef2fba48bf879af1badd82978c
Autor:
You-Wei Fan, Wan-Hsin Liu, Yun-Ti Chen, Yen-Chao Hsu, Nikhil Pathak, Yu-Wei Huang, Jinn-Moon Yang
Publikováno v:
BMC Bioinformatics, Vol 23, Iss S4, Pp 1-17 (2022)
Abstract Background While it has been known that human protein kinases mediate most signal transductions in cells and their dysfunction can result in inflammatory diseases and cancers, it remains a challenge to find effective kinase inhibitor as drug
Externí odkaz:
https://doaj.org/article/e537cc754f024ceeb96fda93cc9b5961
Autor:
Yu-Wei Huang, Yen-Chao Hsu, Yi-Hsuan Chuang, Yun-Ti Chen, Xiang-Yu Lin, You-Wei Fan, Nikhil Pathak, Jinn-Moon Yang
Publikováno v:
BMC Bioinformatics, Vol 23, Iss S4, Pp 1-13 (2022)
Abstract Background Human protein kinases play important roles in cancers, are highly co-regulated by kinase families rather than a single kinase, and complementarily regulate signaling pathways. Even though there are > 100,000 protein kinase inhibit
Externí odkaz:
https://doaj.org/article/82a0cd673e1d49fdabb77c7a5444370a
Autor:
Lucas Borges dos Santos, Alexandre Hild Aono, Felipe Roberto Francisco, Carla Cristina da Silva, Livia Moura Souza, Anete Pereira de Souza
Publikováno v:
Frontiers in Plant Science, Vol 14 (2023)
The protein kinase (PK) superfamily constitutes one of the largest and most conserved protein families in eukaryotic genomes, comprising core components of signaling pathways in cell regulation. Despite its remarkable relevance, only a few kinase fam
Externí odkaz:
https://doaj.org/article/a694f3497af54dda9f610056ecc02387
Autor:
Jie Xiao, Hao Chen, Ruoyu Zheng, Jiayan Pu, Xiaobin Gu, Yue Xie, Ran He, Jing Xu, Bo Jing, Xuerong Peng, Guangyou Yang
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
One of the most common rabbits coccidia species, Eimeria magna is mainly parasitic in the ileal and jejunal epithelial cells. E. magna infection can affect the growth performance of rabbits or cause other secondary diseases. Traditional methods of an
Externí odkaz:
https://doaj.org/article/af7d4092e1014a3badb0261df2d38835
Publikováno v:
Zhongguo linchuang yanjiu, Vol 35, Iss 12, Pp 1643-1646,1652 (2022)
Objective To explore the mechanism of secondary resistance to imatinib(IM) in gastrointestinal stromal tumors(GIST). Methods Ten IM-resistant and ten IM-sensitive GIST patients admitted to the First Affiliated Hospital with Nanjing Medical University
Externí odkaz:
https://doaj.org/article/9823bcdc4da948768802186d2207f5a9
Autor:
Yi-Jing Meng, Bing-Jin Mu, Xiao-Xin Liu, Lin-Mei Yu, Wen-Bin Zheng, Shi-Chen Xie, Wen-Wei Gao, Xing-Quan Zhu, Qing Liu
Publikováno v:
Frontiers in Veterinary Science, Vol 9 (2022)
Though a number of Eimeria tenella rhoptry kinase family proteins have been identified, little is known about their molecular functions. In the present study, the gene fragment encoding the matured peptide of E. tenella rhoptry kinase family protein
Externí odkaz:
https://doaj.org/article/0a044b4f0dc84ce08bf145379237cbb0