Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Kinarm Ko"'
Publikováno v:
Stem Cell Research, Vol 77, Iss , Pp 103416- (2024)
A human induced pluripotent stem cell (iPSC) line (KKUi002-A) was generated from a skin fibroblast of a 57-years-old (at sampling) male patient diagnosed with a sporadic Parkinson’s disease (PD). A non-integration system was used to reprogram fibro
Externí odkaz:
https://doaj.org/article/18f91f4a73954cba8a2a94007eb953f9
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2024)
Neural stem cells (NSCs) are defined by their ability to self-renew and generate various cell types within the nervous system. Understanding the underlying mechanism by which NSCs proliferate and differentiate is crucial for the efficient modulation
Externí odkaz:
https://doaj.org/article/8fa014e164304c9e99ceb0b56e800c48
Autor:
Jin Ju Park, Yang Woo Kwon, Jeong Won Kim, Gyu Tae Park, Jung Won Yoon, Ye Seul Kim, Da Sol Kim, Sang Mo Kwon, Sun Sik Bae, Kinarm Ko, Chang‐Seok Kim, Jae Ho Kim
Publikováno v:
Stem Cells Translational Medicine, Vol 10, Iss 3, Pp 414-426 (2021)
Abstract Critical limb ischemia is a condition in which tissue necrosis occurs due to arterial occlusion, resulting in limb amputation in severe cases. Both endothelial cells (ECs) and vascular smooth muscle cells (SMCs) are needed for the regenerati
Externí odkaz:
https://doaj.org/article/a17c1447f75744ffa9d3ec363982dae4
Autor:
Yo Seph Park, Yukyeong Lee, Na Young Choi, Han Sung Hwang, Stefan Rose-John, Martin Zenke, Kinarm Ko
Publikováno v:
Biochemistry and Biophysics Reports, Vol 29, Iss , Pp 101214- (2022)
Umbilical cord blood (UCB) is an alternative source of allogeneic hematopoietic stem cells (HSCs) for transplantation to treat various hematological disorders. The major limitation to the use of UCB-derived HSCs (UCB–HSCs) in transplantation, howev
Externí odkaz:
https://doaj.org/article/165a477adb6f4688b4908ad90210630b
Publikováno v:
Stem Cell Research, Vol 55, Iss , Pp 102484- (2021)
Bone marrow-derived mesenchymal stem cells (BM-MSCs) possess excellent therapeutic potential for the treatment of various diseases including graft-versus-host disease, rheumatoid arthritis, osteoarthritis, and multiple sclerosis. Here, we generated a
Externí odkaz:
https://doaj.org/article/d558f54685a34266b95ec8354a6284ec
Autor:
Yukyeong Lee, Minseong Lee, Seung-Won Lee, Na Yong Choi, Seokbeom Ham, Hye Jeong Lee, Kisung Ko, Kinarm Ko
Publikováno v:
Animal Cells and Systems, Vol 23, Iss 6, Pp 392-398 (2019)
Spermatogonial stem cells (SSCs) are unipotent adult stem cells, capable of differentiating into sperm cells. SSCs can be cultured in vitro for a long time. SSCs expressing Oct4, a pluripotency marker, and are the only adult cells which pluripotency
Externí odkaz:
https://doaj.org/article/af4196d927f943cfb5c8fb7925dffd1b
Autor:
Kibum Kim, Yang Joo Kang, Se Ra Park, Do-Sun Kim, Seung-Won Lee, Kinarm Ko, Daniel Ponndorf, Kisung Ko
Publikováno v:
PeerJ, Vol 9, p e10851 (2021)
Immunization with thetumor-associated antigen GA733 glycoprotein, which is highly expressed in colorectal cancer, is considered to be a promising strategy for cancer prevention and treatment. We cloned a fusion gene of GA733 and immunoglobulin Fc fra
Externí odkaz:
https://doaj.org/article/0ab57a0dee25463099d82fe8dc21164b
Autor:
Minseong Lee, Na Young Choi, Soree Park, Jin Seok Bang, Yukyeong Lee, Dahee Jeong, Seokbeom Ham, Sohee Lim, Kyun-Hwan Kim, Kinarm Ko
Publikováno v:
Stem Cell Research, Vol 48, Iss , Pp 101943- (2020)
OCT4 and NANOG are core transcription factor genes in self-renewal, differentiation, and reprogramming. Here, we generated an OCT4-EGFP, NANOG-tdTomato dual reporter hiPSC line, KKUi001-A, on the basis of human induced pluripotent stem cells using CR
Externí odkaz:
https://doaj.org/article/539ee3a8e88a425d938a95073b7110c1
Autor:
Na Young Choi, Jin Seok Bang, Hye Jeong Lee, Yo Seph Park, Minseong Lee, Dahee Jeong, Kisung Ko, Dong Wook Han, Hyung-Min Chung, Gwang Jun Kim, Seung-Hyuk Shim, Han Sung Hwang, Kinarm Ko
Publikováno v:
Epigenetics, Vol 13, Iss 4, Pp 343-351 (2018)
Genomic imprinting is the process of epigenetic modification whereby genes are expressed in a parent-of-origin dependent manner; it plays an important role in normal growth and development. Parthenogenetic embryos contain only the maternal genome. Pa
Externí odkaz:
https://doaj.org/article/a27874b66dd345059bc52bb327537386
Autor:
Jin Seok Bang, Na Young Choi, Minseong Lee, Kisung Ko, Hye Jeong Lee, Yo Seph Park, Dahee Jeong, Hyung-Min Chung, Kinarm Ko
Publikováno v:
Animal Cells and Systems, Vol 22, Iss 2, Pp 132-139 (2018)
Generation of induced pluripotent stem cells (iPSCs) by defined factors (OCT4, SOX2, C-MYC, and KLF4) from various human primary cells has been reported. Human fibroblasts have been widely used as a cellular source in reprogramming studies over recen
Externí odkaz:
https://doaj.org/article/49b6acc65e1f46d4b0d6441f76f7bb60